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Automated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep learning methods. However, many of these…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Yifeng Wang , Ke Chen , Haohan Wang

Early and accurate diagnosis of Alzheimer's disease (AD), a complex neurodegenerative disorder, requires analysis of heterogeneous biomarkers (e.g., neuroimaging, genetic risk factors, cognitive tests, and cerebrospinal fluid proteins)…

Computation and Language · Computer Science 2025-10-16 Sophie Kearney , Shu Yang , Zixuan Wen , Bojian Hou , Duy Duong-Tran , Tianlong Chen , Jason Moore , Marylyn Ritchie , Li Shen

Accurate diagnosis of Alzheimer's disease (AD) requires handling tabular biomarker data, yet such data are often small and incomplete, where deep learning models frequently fail to outperform classical methods. Pretrained large language…

Computation and Language · Computer Science 2026-03-19 Sophie Kearney , Shu Yang , Zixuan Wen , Weimin Lyu , Bojian Hou , Duy Duong-Tran , Tianlong Chen , Jason H. Moore , Marylyn D. Ritchie , Chao Chen , Li Shen

Detecting Alzheimer's disease (AD) from narrative transcripts challenges large language models (LLMs): pre-training rarely covers this out-of-distribution task, and all transcript demos describe the same scene, producing highly homogeneous…

Computation and Language · Computer Science 2025-11-11 Puzhen Su , Haoran Yin , Yongzhu Miao , Jintao Tang , Shasha Li , Ting Wang

The accurate diagnosis of Alzheimer's disease (AD) and prognosis of mild cognitive impairment (MCI) conversion are crucial for early intervention. However, existing multimodal methods face several challenges, from the heterogeneity of input…

Machine Learning · Computer Science 2025-03-20 Chenyu Liu , Luca Rossi

Deep learning (DL) has been used in the automatic diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) with brain imaging data. However, previous methods have not fully exploited the relation between brain image and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Luoyao Kang , Haifan Gong , Xiang Wan , Haofeng Li

Neurological conditions, such as Alzheimer's Disease, are challenging to diagnose, particularly in the early stages where symptoms closely resemble healthy controls. Existing brain network analysis methods primarily focus on graph-based…

Neurons and Cognition · Quantitative Biology 2025-05-20 Jiaxing Xu , Kai He , Yue Tang , Wei Li , Mengcheng Lan , Xia Dong , Yiping Ke , Mengling Feng

We introduce Scaffold Prompt Tuning (ScaPT), a novel prompt-based framework for adapting large-scale functional magnetic resonance imaging (fMRI) pre-trained models to downstream tasks, with high parameter efficiency and improved…

Neurons and Cognition · Quantitative Biology 2024-08-21 Zijian Dong , Yilei Wu , Zijiao Chen , Yichi Zhang , Yueming Jin , Juan Helen Zhou

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and to delay further progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical…

Computation and Language · Computer Science 2023-04-03 Yi Wang , Jiajun Deng , Tianzi Wang , Bo Zheng , Shoukang Hu , Xunying Liu , Helen Meng

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that leads to dementia, and early intervention can greatly benefit from analyzing linguistic abnormalities. In this work, we explore the potential of Large Language Models…

Computation and Language · Computer Science 2025-12-23 Chuyuan Li , Raymond Li , Thalia S. Field , Giuseppe Carenini

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

Tabular data is one of the most ubiquitous sources of information worldwide, spanning a wide variety of domains. This inherent heterogeneity has slowed the development of Tabular Foundation Models (TFMs) capable of fast generalization to…

Prompt tuning, like CoOp, has recently shown promising vision recognizing and transfer learning ability on various downstream tasks with the emergence of large pre-trained vision-language models like CLIP. However, we identify that existing…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yongzhu Miao , Shasha Li , Jintao Tang , Ting Wang

Accurate diagnosis of Alzheimer's disease (AD) requires effectively integrating multimodal data and clinical expertise. However, existing methods often struggle to fully utilize multimodal information and lack structured mechanisms to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Qiuhui Chen , Jintao Wang , Gang Wang , Yi Hong

In-context learning (ICL) is a few-shot learning paradigm that involves learning mappings through input-output pairs and appropriately applying them to new instances. Despite the remarkable ICL capabilities demonstrated by Large Language…

Computation and Language · Computer Science 2024-08-06 Peng Wang , Xiaobin Wang , Chao Lou , Shengyu Mao , Pengjun Xie , Yong Jiang

Prompt learning is one of the most effective paradigms for adapting pre-trained vision-language models (VLMs) to the biomedical image classification tasks in few shot scenarios. However, most of the current prompt learning methods only used…

Computer Vision and Pattern Recognition · Computer Science 2025-05-09 Wei Peng , Kang Liu , Jianchen Hu , Meng Zhang

Vision-language foundation models (VLMs) have shown great potential in feature transfer and generalization across a wide spectrum of medical-related downstream tasks. However, fine-tuning these models is resource-intensive due to their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ye Du , Nanxi Yu , Shujun Wang

Recent years have witnessed increasing interests in prompt-based learning in which models can be trained on only a few annotated instances, making them suitable in low-resource settings. When using prompt-based learning for text…

Computation and Language · Computer Science 2023-05-11 Hongjing Li , Hanqi Yan , Yanran Li , Li Qian , Yulan He , Lin Gui

Fine-tuning Large Language Models (LLMs) typically involves updating at least a few billions of parameters. A more parameter-efficient approach is Prompt Tuning (PT), which updates only a few learnable tokens, and differently, In-Context…

Computation and Language · Computer Science 2024-10-23 Tsachi Blau , Moshe Kimhi , Yonatan Belinkov , Alexander Bronstein , Chaim Baskin

Alzheimer's Disease (AD) is the most prevalent neurodegenerative disorder in aging populations, posing a significant and escalating burden on global healthcare systems. While Multi-Tusk Learning (MTL) has emerged as a powerful computational…

Machine Learning · Computer Science 2025-10-14 Zixiang Xu , Menghui Zhou , Jun Qi , Xuanhan Fan , Yun Yang , Po Yang
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