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Healthy tissue inpainting has significant applications, including the generation of pseudo-healthy baselines for tumor growth models and the facilitation of image registration. In previous editions of the BraTS Local Synthesis of Healthy…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Alicia Durrer , Florentin Bieder , Paul Friedrich , Bjoern Menze , Philippe C. Cattin , Florian Kofler

Diffusion-based voxel prior modelling is challenging for the reconstruction of large-scale 3D porous microstructures. Due to the demanding requirements for simultaneously modelling both the continuous pore morphology and the discrete…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Yue Shi , Peng Wang , Mingzhe Yu , Yunlong Zhao , Li Liu , Gareth D Hatton , Yan Lyu , Liangxiu Han

Analysis of three-dimensional biological samples is critical to understanding tissue function and the mechanisms of disease. Many chronic conditions, like neurodegenerative diseases and cancers, correlate with complex tissue changes that…

Biological Physics · Physics 2019-11-06 Jiaming Guo , Camille Artur , Jason L. Eriksen , David Mayerich

Solving 3D medical inverse problems such as image restoration and reconstruction is crucial in modern medical field. However, the curse of dimensionality in 3D medical data leads mainstream volume-wise methods to suffer from high resource…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Jia He , Bonan Li , Ge Yang , Ziwen Liu

Deep learning affords enormous opportunities to augment the armamentarium of biomedical imaging, albeit its design and implementation have potential flaws. Fundamentally, most deep learning models are driven entirely by data without…

Computer Vision and Pattern Recognition · Computer Science 2021-05-26 Liyue Shen , Wei Zhao , Dante Capaldi , John Pauly , Lei Xing

Deep learning and generative models are advancing rapidly, with synthetic data increasingly being integrated into training pipelines for downstream analysis tasks. However, in medical imaging, their adoption remains constrained by the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Kyeonghun Kim , Jaehyeok Bae , Youngung Han , Joo Young Bae , Seoyoung Ju , Junsu Lim , Gyeongmin Kim , Nam-Joon Kim , Woo Kyoung Jeong , Ken Ying-Kai Liao , Won Jae Lee , Pa Hong , Hyuk-Jae Lee

While high-resolution microscopic techniques are crucial for studying cellular structures in cell biology, obtaining such images from thick 3D engineered tissues remains challenging. In this review, we explore advancements in fluorescence…

Tissues and Organs · Quantitative Biology 2025-02-07 Yasaman Kargar Gaz Kooh , Nathaniel Huebsch

Volumetric biological imaging often involves compromising high temporal resolution at the expense of high spatial resolution when popular scanning methods are used to capture 3D information. We introduce an integrated experimental and image…

Neuroimaging to neuropathology correlation (NTNC) promises to enable the transfer of microscopic signatures of pathology to in vivo imaging with MRI, ultimately enhancing clinical care. NTNC traditionally requires a volumetric MRI scan,…

Recent years have witnessed the remarkable performance of diffusion models in various vision tasks. However, for image restoration that aims to recover clear images with sharper details from given degraded observations, diffusion-based…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Liyan Wang , Qinyu Yang , Cong Wang , Wei Wang , Jinshan Pan , Zhixun Su

Neural reconstruction approaches are rapidly emerging as the preferred representation for 3D scenes, but their limited editability is still posing a challenge. In this work, we propose an approach for 3D scene inpainting -- the task of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Ashkan Mirzaei , Riccardo De Lutio , Seung Wook Kim , David Acuna , Jonathan Kelly , Sanja Fidler , Igor Gilitschenski , Zan Gojcic

Applying machine learning to real-world medical data, e.g. from hospital archives, has the potential to revolutionize disease detection in brain images. However, detecting pathology in such heterogeneous cohorts is a difficult challenge.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Ana Lawry Aguila , Ayodeji Ijishakin , Juan Eugenio Iglesias , Tomomi Takenaga , Yukihiro Nomura , Takeharu Yoshikawa , Osamu Abe , Shouhei Hanaoka

Synthesizing high-quality images from low-field MRI holds significant potential. Low-field MRI is cheaper, more accessible, and safer, but suffers from low resolution and poor signal-to-noise ratio. This synthesis process can reduce…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Zhenxuan Zhang , Peiyuan Jing , Zi Wang , Ula Briski , Coraline Beitone , Yue Yang , Yinzhe Wu , Fanwen Wang , Liutao Yang , Jiahao Huang , Zhifan Gao , Zhaolin Chen , Kh Tohidul Islam , Guang Yang , Peter J. Lally

In recent years, the denoising diffusion model has achieved remarkable success in image segmentation modeling. With its powerful nonlinear modeling capabilities and superior generalization performance, denoising diffusion models have…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Weiping Ding , Sheng Geng , Haipeng Wang , Jiashuang Huang , Tianyi Zhou

Unsupervised anomaly detection has gained significant attention in the field of medical imaging due to its capability of relieving the costly pixel-level annotation. To achieve this, modern approaches usually utilize generative models to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Rui Xu , Yunke Wang , Bo Du

Denoising diffusion models have recently achieved state-of-the-art performance in many image-generation tasks. They do, however, require a large amount of computational resources. This limits their application to medical tasks, where we…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Florentin Bieder , Julia Wolleb , Alicia Durrer , Robin Sandkühler , Philippe C. Cattin

Discrete diffusion models generate sequences by iteratively denoising samples corrupted by categorical noise, offering an appealing alternative to autoregressive decoding for structured and symbolic generation. However, standard training…

Machine Learning · Computer Science 2026-02-04 Huu Binh Ta , Michael Cardei , Alvaro Velasquez , Ferdinando Fioretto

Training deep neural networks has become a common approach for addressing image restoration problems. An alternative for training a "task-specific" network for each observation model is to use pretrained deep denoisers for imposing only the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Tomer Garber , Tom Tirer

Exploiting pre-trained diffusion models for restoration has recently become a favored alternative to the traditional task-specific training approach. Previous works have achieved noteworthy success by limiting the solution space using…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Peiqing Yang , Shangchen Zhou , Qingyi Tao , Chen Change Loy

Low-dose computed tomography (CT) denoising is crucial for reduced radiation exposure while ensuring diagnostically acceptable image quality. Despite significant advancements driven by deep learning (DL) in recent years, existing DL-based…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Zhihao Chen , Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Jun Zhao , Hongming Shan
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