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Vision-Language Models (VLMs) have shown promise in various 2D visual tasks, yet their readiness for 3D clinical diagnosis remains unclear due to stringent demands for recognition precision, reasoning ability, and domain knowledge. To…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Yixiong Chen , Wenjie Xiao , Pedro R. A. S. Bassi , Xinze Zhou , Sezgin Er , Ibrahim Ethem Hamamci , Zongwei Zhou , Alan Yuille

Medical vision-language models (VLMs) show strong performance on radiology tasks but often produce fluent yet weakly grounded conclusions due to over-reliance on a dominant modality. We introduce a context-aligned reasoning framework that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Sumra Khan , Sagar Chhabriya , Aizan Zafar , Sheeraz Arif , Amgad Muneer , Anas Zafar , Shaina Raza , Rizwan Qureshi

The rapid advancements in Vision Language Models (VLMs) have prompted the development of multi-modal medical assistant systems. Despite this progress, current models still have inherent probabilistic uncertainties, often producing erroneous…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Xiao Liang , Di Wang , Zhicheng Jiao , Ronghan Li , Pengfei Yang , Quan Wang , Tat-Seng Chua

Medical vision--language models (VLMs) have shown strong potential for medical visual question answering (VQA), yet their reasoning remains largely text-centric: images are encoded once as static context, and subsequent inference is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Suyang Xi , Songtao Hu , Yuxiang Lai , Wangyun Dan , Yaqi Liu , Shansong Wang , Xiaofeng Yang

Computed Tomography (CT) plays a crucial role in clinical diagnosis, but the growing demand for CT examinations has raised concerns about diagnostic errors. While Multimodal Large Language Models (MLLMs) demonstrate promising comprehension…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Sunggu Kyung , Hyungbin Park , Jinyoung Seo , Jimin Sung , Jihyun Kim , Dongyeong Kim , Wooyoung Jo , Yoojin Nam , Sangah Park , Taehee Kwon , Sang Min Lee , Namkug Kim

Multimodal Large Language Models (MLLMs) have shown remarkable proficiency on general-purpose vision-language benchmarks, reaching or even exceeding human-level performance. However, these evaluations typically rely on standard…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Wenjin Hou , Wei Liu , Han Hu , Xiaoxiao Sun , Serena Yeung-Levy , Hehe Fan

Recent advancements in Large Vision-Language Models (LVLMs) have demonstrated remarkable capabilities across diverse tasks, garnering significant attention in AI communities. However, their performance and reliability in specialized domains…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Yang Nan , Huichi Zhou , Xiaodan Xing , Guang Yang

Vision-language models (VLMs) exhibit strong zero-shot generalization on natural images and show early promise in interpretable medical image analysis. However, existing benchmarks do not systematically evaluate whether these models truly…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Tianhong Zhou , Yin Xu , Yingtao Zhu , Chuxi Xiao , Haiyang Bian , Lei Wei , Xuegong Zhang

Large language models (LLMs) show promise in medical diagnosis, but real-world deployment remains challenging due to high-stakes clinical decisions and imperfect reasoning reliability. As a result, careful inspection of model behavior is…

Computation and Language · Computer Science 2026-04-28 Yurui Xiang , Xingyi Mao , Rui Sheng , Zixin Chen , Zelin Zang , Yuyang Wu , Haipeng Zeng , Huamin Qu , Yushi Sun , Yanna Lin

With the growing use of language models (LMs) in clinical environments, there is an immediate need to evaluate the accuracy and safety of LM-generated medical text. Currently, such evaluation relies solely on manual physician review.…

Vision language models (VLMs) achieve strong performance on general image understanding but struggle to think with medical images, especially when performing multi-step reasoning through iterative visual interaction. Medical VLMs often rely…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Meng Lu , Yuxing Lu , Yuchen Zhuang , Megan Mullins , Yang Xie , Guanghua Xiao , Charles Fleming , Wenqi Shi , Xuan Wang

Real-world clinical practice demands multi-image comparative reasoning, yet current medical benchmarks remain limited to single-frame interpretation. We present MedFrameQA, the first benchmark explicitly designed to test multi-image medical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Suhao Yu , Haojin Wang , Juncheng Wu , Luyang Luo , Jingshen Wang , Cihang Xie , Pranav Rajpurkar , Carl Yang , Yang Yang , Kang Wang , Yannan Yu , Yuyin Zhou

Large Vision-Language Models (VLMs) are increasingly used to evaluate outputs of other models, for image-to-text (I2T) tasks such as visual question answering, and text-to-image (T2I) generation tasks. Despite this growing reliance, the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Mohammed Safi Ur Rahman Khan , Sanjay Suryanarayanan , Tushar Anand , Mitesh M. Khapra

While Large Language Models (LLMs) achieve superhuman performance on standardized medical licensing exams, these static benchmarks have become saturated and increasingly disconnected from the functional requirements of clinical workflows.…

Brain tumor diagnosis is largely dependent on Magnetic Resonance Imaging (MRI) evaluation, which requires radiologists to synthesize thousands of images across multiple 3D sequences and longitudinal studies. This process requires advanced…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Shiv Ghosh , Junayd Lateef , Chih-Hua Liu , Yannan Yu , Andreas M. Rauschecker , Madhumita Sushil

In high-stakes medical applications, consistent answering across diverse question phrasings is essential for reliable diagnosis. However, we reveal that current Medical Vision-Language Models (Med-VLMs) exhibit concerning fragility in…

Computation and Language · Computer Science 2025-08-27 Songtao Jiang , Yuxi Chen , Sibo Song , Yan Zhang , Yeying Jin , Yang Feng , Jian Wu , Zuozhu Liu

Explaining Deep Learning models is becoming increasingly important in the face of daily emerging multimodal models, particularly in safety-critical domains like medical imaging. However, the lack of detailed investigations into the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Anees Ur Rehman Hashmi , Dwarikanath Mahapatra , Mohammad Yaqub

Vision-language models (VLMs) are increasingly adapted through domain-specific fine-tuning, yet it remains unclear whether this improves reasoning beyond superficial visual cues, particularly in high-stakes domains like medicine. We…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Oliver McLaughlin , Daniel Shubin , Carsten Eickhoff , Ritambhara Singh , William Rudman , Michal Golovanevsky

While Multimodal Large Language Models (MLLMs) show promising performance in automated electrocardiogram interpretation, it remains unclear whether they genuinely perform actual step-by-step reasoning or just rely on superficial visual…

Machine Learning · Computer Science 2026-03-17 Jungwoo Oh , Hyunseung Chung , Junhee Lee , Min-Gyu Kim , Hangyul Yoon , Ki Seong Lee , Youngchae Lee , Muhan Yeo , Edward Choi

Medical large vision-language models (LVLMs) have demonstrated promising performance across various single-image question answering (QA) benchmarks, yet their capability in processing multi-image clinical scenarios remains underexplored.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Xikai Yang , Juzheng Miao , Yuchen Yuan , Jiaze Wang , Qi Dou , Jinpeng Li , Pheng-Ann Heng