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Foundation models (FMs) promise to generalize medical imaging, but their effectiveness varies. It remains unclear how pre-training domain (medical vs. general), paradigm (e.g., text-guided), and architecture influence embedding quality,…

Despite the significant potential of Foundation Models (FMs) in medical imaging, their application to prognosis prediction remains challenging due to data scarcity, class imbalance, and task complexity, which limit their clinical adoption.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Filippo Ruffini , Elena Mulero Ayllon , Linlin Shen , Paolo Soda , Valerio Guarrasi

Background: The high dimensionality of radiomic feature sets, the variability in radiomic feature types and potentially high computational requirements all underscore the need for an effective method to identify the smallest set of…

Purpose: To identify optimal classification methods for computed tomography (CT) radiomics-based preoperative prediction of clear cells renal cell carcinoma (ccRCC) grade. Methods and material: Seventy one ccRCC patients were included in…

Foundation models have transformed medical image analysis by providing robust feature representations that reduce the need for large-scale task-specific training. However, current benchmarks in dermatology often reduce the complex…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Furkan Yuceyalcin , Abdurrahim Yilmaz , Burak Temelkuran

Background: Accurate lesion segmentation is critical for multiple sclerosis (MS) diagnosis, yet current deep learning approaches face robustness challenges. Aim: This study improves MS lesion segmentation by combining data fusion and deep…

Image and Video Processing · Electrical Eng. & Systems 2025-06-18 Nadezhda Alsahanova , Pavel Bartenev , Maksim Sharaev , Milos Ljubisavljevic , Taleb Al. Mansoori , Yauhen Statsenko

Foundation models (FMs) have shown transformative potential in radiology by performing diverse, complex tasks across imaging modalities. Here, we developed CT-FM, a large-scale 3D image-based pre-trained model designed explicitly for…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Suraj Pai , Ibrahim Hadzic , Dennis Bontempi , Keno Bressem , Benjamin H. Kann , Andriy Fedorov , Raymond H. Mak , Hugo J. W. L. Aerts

Neuro-oncology poses unique challenges for machine learning due to heterogeneous data and tumor complexity, limiting the ability of foundation models (FMs) to generalize across cohorts. Existing FMs also perform poorly in predicting…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Moinak Bhattacharya , Angelica P. Kurtz , Fabio M. Iwamoto , Prateek Prasanna , Gagandeep Singh

Foundation models provide robust embeddings for diverse tasks, including medical imaging. We evaluate embeddings from seven general and medical-specific foundation models (e.g., DenseNet121, BiomedCLIP, MedImageInsight, Rad-DINO,…

Foundation models (FMs), large neural networks pretrained on extensive and diverse datasets, have revolutionized artificial intelligence and shown significant promise in medical imaging by enabling robust performance with limited labeled…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Salah Ghamizi , Georgia Kanli , Yu Deng , Magali Perquin , Olivier Keunen

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot performance across diverse medical imaging tasks, from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Praveenbalaji Rajendran , Mojtaba Safari , Wenfeng He , Mingzhe Hu , Shansong Wang , Jun Zhou , Xiaofeng Yang

Pathology Foundation Models (FMs) hold great promise for healthcare. Before they can be used in clinical practice, it is essential to ensure they are robust to variations between medical centers. We measure whether pathology FMs focus on…

Machine Learning · Computer Science 2025-02-04 Edwin D. de Jong , Eric Marcus , Jonas Teuwen

Foundation models, often pre-trained with large-scale data, have achieved paramount success in jump-starting various vision and language applications. Recent advances further enable adapting foundation models in downstream tasks efficiently…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Dequan Wang , Xiaosong Wang , Lilong Wang , Mengzhang Li , Qian Da , Xiaoqiang Liu , Xiangyu Gao , Jun Shen , Junjun He , Tian Shen , Qi Duan , Jie Zhao , Kang Li , Yu Qiao , Shaoting Zhang

Ultrasound is widely used in obstetric care due to its safety, accessibility, and real-time imaging. However, interpretation remains operator-dependent and susceptible to noise and artifacts. Deep learning models have shown strong…

Image and Video Processing · Electrical Eng. & Systems 2026-05-28 Leya Barrientos , Yuexi Du , Nicha C. Dvornek

Renal tumors, especially renal cell carcinoma (RCC), show significant heterogeneity, posing challenges for diagnosis using radiology images such as MRI, echocardiograms, and CT scans. U-Net based deep learning techniques are emerging as a…

Artificial Intelligence · Computer Science 2024-10-23 Fnu Neha , Arvind K. Bansal

Recent foundation models have demonstrated strong performance in medical image representation learning, yet their comparative behaviour across datasets remains underexplored. This work benchmarks two large-scale chest X-ray (CXR) embedding…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Jiho Shin , Dominic Marshall , Matthieu Komorowski

Accurate subtyping of renal cell carcinoma (RCC) is of crucial importance for understanding disease progression and for making informed treatment decisions. New discoveries of significant alterations to mitochondria between subtypes make…

Machine Learning · Computer Science 2016-08-03 Peter J. Schüffler , Judy Sarungbam , Hassan Muhammad , Ed Reznik , Satish K. Tickoo , Thomas J. Fuchs

Over the past decades, computer-aided diagnosis tools for breast cancer have been developed to enhance screening procedures, yet their clinical adoption remains challenged by data variability and inherent biases. Although foundation models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Elodie Germani , Ilayda Selin Türk , Fatima Zeineddine , Charbel Mourad , Shadi Albarqouni

Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ken Enda , Yoshitaka Oda , Zen-ichi Tanei , Kenichi Satoh , Hiroaki Motegi , Terasaka Shunsuke , Shigeru Yamaguchi , Takahiro Ogawa , Wang Lei , Masumi Tsuda , Shinya Tanaka
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