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In this paper, we introduce a denoising diffusion algorithm to discover microstructures with nonlinear fine-tuned properties. Denoising diffusion probabilistic models are generative models that use diffusion-based dynamics to gradually…

Machine Learning · Computer Science 2023-06-14 Nikolaos N. Vlassis , WaiChing Sun

As Diffusion Models have shown promising performance, a lot of efforts have been made to improve the controllability of Diffusion Models. However, how to train Diffusion Models to have the disentangled latent spaces and how to naturally…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Wonwoong Cho , Hareesh Ravi , Midhun Harikumar , Vinh Khuc , Krishna Kumar Singh , Jingwan Lu , David I. Inouye , Ajinkya Kale

Diffusion models have emerged as preeminent contenders in the realm of generative models. Distinguished by their distinctive sequential generative processes, characterized by hundreds or even thousands of timesteps, diffusion models…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Haojun Sun , Chen Tang , Zhi Wang , Yuan Meng , Jingyan jiang , Xinzhu Ma , Wenwu Zhu

Few-shot image synthesis entails generating diverse and realistic images of novel categories using only a few example images. While multiple recent efforts in this direction have achieved impressive results, the existing approaches are…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Parul Gupta , Munawar Hayat , Abhinav Dhall , Thanh-Toan Do

Diffusion models have recently brought a powerful revolution in image generation. Despite showing impressive generative capabilities, most of these models rely on the current sample to denoise the next one, possibly resulting in denoising…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Yurui Qian , Qi Cai , Yingwei Pan , Yehao Li , Ting Yao , Qibin Sun , Tao Mei

Diffusion Probabilistic Models (DPMs) have achieved great success in image generation but suffer from high inference latency due to their iterative denoising nature. Motivated by the evolving feature dynamics across the denoising…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Haodong He , Yuan Gao , Weizhong Zhang , Gui-Song Xia

Recent empirical studies have demonstrated that diffusion models can effectively learn the image distribution and generate new samples. Remarkably, these models can achieve this even with a small number of training samples despite a large…

Machine Learning · Computer Science 2025-07-08 Peng Wang , Huijie Zhang , Zekai Zhang , Siyi Chen , Yi Ma , Qing Qu

Modern successes of diffusion models in learning complex, high-dimensional data distributions are attributed, in part, to their capability to construct diffusion processes with analytic transition kernels and score functions. The…

Machine Learning · Statistics 2024-03-01 Guan-Horng Liu , Tianrong Chen , Evangelos A. Theodorou , Molei Tao

Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Pamela Osuna-Vargas , Maren H. Wehrheim , Lucas Zinz , Johanna Rahm , Ashwin Balakrishnan , Alexandra Kaminer , Mike Heilemann , Matthias Kaschube

Diffusion Probabilistic Models (DPMs) are generative models showing competitive performance in various domains, including image synthesis and 3D point cloud generation. Sampling from pre-trained DPMs involves multiple neural function…

Machine Learning · Computer Science 2025-05-21 Vinh Tong , Hoang Trung-Dung , Anji Liu , Guy Van den Broeck , Mathias Niepert

Many protein design applications, such as binder or enzyme design, require scaffolding a structural motif with high precision. Generative modelling paradigms based on denoising diffusion processes emerged as a leading candidate to address…

Machine Learning · Computer Science 2024-03-15 Kieran Didi , Francisco Vargas , Simon V Mathis , Vincent Dutordoir , Emile Mathieu , Urszula J Komorowska , Pietro Lio

We provide a general framework for learning diffusion bridges that transport prior to target distributions. It includes existing diffusion models for generative modeling, but also underdamped versions with degenerate diffusion matrices,…

Machine Learning · Computer Science 2025-08-14 Denis Blessing , Julius Berner , Lorenz Richter , Gerhard Neumann

SDE-based methods such as denoising diffusion probabilistic models (DDPMs) have shown remarkable success in real-world sample generation tasks. Prior analyses of DDPMs have been focused on the exponential Euler discretization, showing…

Machine Learning · Computer Science 2025-11-10 Matthew S. Zhang , Stephen Huan , Jerry Huang , Nicholas M. Boffi , Sitan Chen , Sinho Chewi

Diffusion models are an important tool for generative modelling, serving as effective priors in applications such as imaging and protein design. A key challenge in applying diffusion models for downstream tasks is efficiently sampling from…

Machine Learning · Computer Science 2026-02-12 Alexander Denker , Shreyas Padhy , Francisco Vargas , Johannes Hertrich

Diffusion models have recently exhibited remarkable abilities to synthesize striking image samples since the introduction of denoising diffusion probabilistic models (DDPMs). Their key idea is to disrupt images into noise through a fixed…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Zijian Zhang , Zhou Zhao , Jun Yu , Qi Tian

We develop numerical methods for reaction-diffusion systems based on the equations of fluctuating hydrodynamics (FHD). While the FHD formulation is formally described by stochastic partial differential equations (SPDEs), it becomes similar…

Fluid Dynamics · Physics 2018-01-17 Changho Kim , Andy Nonaka , John B. Bell , Alejandro L. Garcia , Aleksandar Donev

Denoising diffusion probabilistic models have brought tremendous advances in generative tasks, achieving state-of-the-art performance thus far. Current diffusion model-based applications exploit the power of learned visual representations…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Changgyoon Oh , Jongoh Jeong , Jegyeong Cho , Kuk-Jin Yoon

Generative modelling over continuous-time geometric constructs, a.k.a such as handwriting, sketches, drawings etc., have been accomplished through autoregressive distributions. Such strictly-ordered discrete factorization however falls…

Machine Learning · Computer Science 2023-04-11 Ayan Das , Yongxin Yang , Timothy Hospedales , Tao Xiang , Yi-Zhe Song

Generative models have made significant impacts across various domains, largely due to their ability to scale during training by increasing data, computational resources, and model size, a phenomenon characterized by the scaling laws.…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Nanye Ma , Shangyuan Tong , Haolin Jia , Hexiang Hu , Yu-Chuan Su , Mingda Zhang , Xuan Yang , Yandong Li , Tommi Jaakkola , Xuhui Jia , Saining Xie

Denoising diffusion models (DDMs) have led to staggering performance leaps in image generation, editing and restoration. However, existing DDMs use very large datasets for training. Here, we introduce a framework for training a DDM on a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-08 Vladimir Kulikov , Shahar Yadin , Matan Kleiner , Tomer Michaeli