English
Related papers

Related papers: Unlocking High-Fidelity Molecular Generation from …

200 papers

Most real-world networks are noisy and incomplete samples from an unknown target distribution. Refining them by correcting corruptions or inferring unobserved regions typically improves downstream performance. Inspired by the impressive…

We propose GraphNVP, the first invertible, normalizing flow-based molecular graph generation model. We decompose the generation of a graph into two steps: generation of (i) an adjacency tensor and (ii) node attributes. This decomposition…

Machine Learning · Statistics 2019-05-29 Kaushalya Madhawa , Katushiko Ishiguro , Kosuke Nakago , Motoki Abe

Generative models have the potential to accelerate key steps in the discovery of novel molecular therapeutics and materials. Diffusion models have recently emerged as a powerful approach, excelling at unconditional sample generation and,…

Biomolecules · Quantitative Biology 2024-07-17 Leo Klarner , Tim G. J. Rudner , Garrett M. Morris , Charlotte M. Deane , Yee Whye Teh

Text-conditioned image generation has made significant progress in recent years with generative adversarial networks and more recently, diffusion models. While diffusion models conditioned on text prompts have produced impressive and…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Azade Farshad , Yousef Yeganeh , Yu Chi , Chengzhi Shen , Björn Ommer , Nassir Navab

Autoregressive (AR) generation is the standard decoding paradigm for Large Language Models (LLMs), but its token-by-token nature limits parallelism at inference time. Diffusion Language Models (DLLMs) offer parallel decoding by recovering…

Computation and Language · Computer Science 2025-12-30 Aiwei Liu , Minghua He , Shaoxun Zeng , Sijun Zhang , Linhao Zhang , Chuhan Wu , Wei Jia , Yuan Liu , Xiao Zhou , Jie Zhou

Continuous graph neural models based on differential equations have expanded the architecture of graph neural networks (GNNs). Due to the connection between graph diffusion and message passing, diffusion-based models have been widely…

Machine Learning · Computer Science 2024-04-01 Kaiyuan Cui , Xinyan Wang , Zicheng Zhang , Weichen Zhao

Generative recommendation (GR) is an emerging paradigm that represents each item via a tokenizer as an n-digit semantic ID (SID) and predicts the next item by autoregressively generating its SID conditioned on the user's history. However,…

Information Retrieval · Computer Science 2025-10-28 Zhao Liu , Yichen Zhu , Yiqing Yang , Guoping Tang , Rui Huang , Qiang Luo , Xiao Lv , Ruiming Tang , Kun Gai , Guorui Zhou

Knowledge Graphs (KGs) have proven highly effective for recommendation systems by capturing latent item relationships, while recent integration of Large Language Models (LLMs) has further enhanced semantic understanding and addressed…

Information Retrieval · Computer Science 2026-05-11 Xinchi Zou , Tongzhenzhi Su , Jianjun Li , Yuan Fu , Chang Liu , Zhiying Deng , Zhiwei Shen

Forecasting over graph-structured sensor networks demands models that capture both deterministic spatial trends and stochastic variability, while remaining efficient enough for repeated inference as new observations arrive. We propose…

Machine Learning · Computer Science 2026-04-02 Hanlin Dong , Arian Prabowo , Hao Xue , Ao Shuang , Tianyi Zhou , Flora D. Salim

Discrete graph generation has emerged as a powerful paradigm for modeling graph data, often relying on highly expressive neural backbones such as transformers or higher-order architectures. We revisit this design choice by introducing…

Machine Learning · Computer Science 2026-03-11 Jay Revolinsky , Harry Shomer , Jiliang Tang

The analogy to heat diffusion has enhanced our understanding of information flow in graphs and inspired the development of Graph Neural Networks (GNNs). However, most diffusion-based GNNs emulate passive heat diffusion, which still suffers…

Machine Learning · Computer Science 2025-10-23 Mengying Jiang

Directed acyclic graphs (DAGs) serve as crucial data representations in domains such as hardware synthesis and compiler/program optimization for computing systems. DAG generative models facilitate the creation of synthetic DAGs, which can…

Machine Learning · Computer Science 2025-03-04 Mufei Li , Viraj Shitole , Eli Chien , Changhai Man , Zhaodong Wang , Srinivas Sridharan , Ying Zhang , Tushar Krishna , Pan Li

Molecule generation is central to a variety of applications. Current attention has been paid to approaching the generation task as subgraph prediction and assembling. Nevertheless, these methods usually rely on hand-crafted or external…

Machine Learning · Computer Science 2022-12-20 Xiangzhe Kong , Wenbing Huang , Zhixing Tan , Yang Liu

Drug discovery can be viewed as a combinatorial search over an immense chemical space, motivating the development of deep generative models for de novo molecular design. Among these, GPT-based molecular language models (MLM) have shown…

Machine Learning · Computer Science 2026-02-02 Qianwei Yang , Dong Xu , Zhangfan Yang , Sisi Yuan , Zexuan Zhu , Jianqiang Li , Junkai Ji

High-order Graph Neural Networks (HO-GNNs) have been developed to infer consistent latent spaces in the heterophilic regime, where the label distribution is not correlated with the graph structure. However, most of the existing HO-GNNs are…

Machine Learning · Computer Science 2023-06-30 Ahmed Begga , Francisco Escolano , Miguel Angel Lozano , Edwin R. Hancock

3D model generation from single 2D RGB images is a challenging and actively researched computer vision task. Various techniques using conventional network architectures have been proposed for the same. However, the body of research work is…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Abdul Mueed Hafiz , Rouf Ul Alam Bhat , Shabir Ahmad Parah , M. Hassaballah

The social graphs synthesized by the generative models are increasingly in demand due to data scarcity and concerns over user privacy. One of the key performance criteria for generating social networks is the fidelity to specified…

Social and Information Networks · Computer Science 2023-11-07 Jui-Yi Tsai , Ya-Wen Teng , Ho Chiok Yew , De-Nian Yang , Lydia Y. Chen

Diffusion-based generative models have significantly advanced text-to-image synthesis, demonstrating impressive text comprehension and zero-shot generalization. These models refine images from random noise based on textual prompts, with…

Machine Learning · Computer Science 2025-05-16 Youcef Djenouri , Nassim Belmecheri , Tomasz Michalak , Jan Dubiński , Ahmed Nabil Belbachir , Anis Yazidi

Most existing text-to-image generation methods adopt a multi-stage modular architecture which has three significant problems: 1) Training multiple networks increases the run time and affects the convergence and stability of the generative…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Zhenxing Zhang , Lambert Schomaker

Diffusion models achieve state-of-the-art performance in generating realistic objects and have been successfully applied to images, text, and videos. Recent work has shown that diffusion can also be defined on graphs, including graph…

Machine Learning · Computer Science 2023-02-09 Alex M. Tseng , Nathaniel Diamant , Tommaso Biancalani , Gabriele Scalia