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The broad applicability of Quadratic Unconstrained Binary Optimization (QUBO) constitutes a general-purpose modeling framework for combinatorial optimization problems and are a required format for gate array and quantum annealing computers.…

Artificial Intelligence · Computer Science 2021-04-06 Amit Verma , Mark Lewis

Computed tomography (CT) is an important imaging technique used in medical analysis of the internal structure of the human body. Previously, image segmentation methods were required after acquiring reconstructed CT images to obtain…

Quantum Physics · Physics 2024-09-17 Kyungtaek Jun

In this paper, we study the computational complexity of the quadratic unconstrained binary optimization (QUBO) problem under the functional problem FP^NP categorization. We focus on four sub-classes: (1) When all coefficients are integers…

Computational Complexity · Computer Science 2022-02-21 Hirotoshi Yasuoka

A core step of every algorithm for learning regression trees is the selection of the best splitting variable from the available covariates and the corresponding split point. Early tree algorithms (e.g., AID, CART) employed greedy search…

Methodology · Statistics 2019-06-26 Lisa Schlosser , Torsten Hothorn , Achim Zeileis

The peptide-protein docking problem is an important problem in structural biology that facilitates rational and efficient drug design. In this work, we explore modeling and solving this problem with the quantum-amenable quadratic…

A range of quantum algorithms, especially those leveraging variational parameterization and circuit-based optimization, are being studied as alternatives for solving classically intractable combinatorial optimization problems (COPs).…

Quantum Physics · Physics 2025-06-18 Monit Sharma , Hoong Chuin Lau

Bayesian additive regression trees (BART) (Chipman et. al., 2010) is a powerful predictive model that often outperforms alternative models at out-of-sample prediction. BART is especially well-suited to settings with unstructured predictor…

Machine Learning · Statistics 2019-03-15 Jingyu He , Saar Yalov , P. Richard Hahn

Decision trees are widely used for classification and regression tasks in a variety of application fields due to their interpretability and good accuracy. During the past decade, growing attention has been devoted to globally optimized…

Machine Learning · Computer Science 2025-01-28 Antonio Consolo , Edoardo Amaldi , Andrea Manno

This paper develops a novel stochastic tree ensemble method for nonlinear regression, which we refer to as XBART, short for Accelerated Bayesian Additive Regression Trees. By combining regularization and stochastic search strategies from…

Machine Learning · Statistics 2021-06-04 Jingyu He , P. Richard Hahn

Motivated by the remarkable success of Bayesian additive regression trees (BART) in regression modelling, we propose a novel nonparametric Bayesian method, termed Functional BART (FBART), tailored specifically for function-on-scalar…

Methodology · Statistics 2025-06-03 Jiahao Cao , Shiyuan He , Bohai Zhang

Bayesian quadrature (BQ) is a method for solving numerical integration problems in a Bayesian manner, which allows users to quantify their uncertainty about the solution. The standard approach to BQ is based on a Gaussian process (GP)…

Methodology · Statistics 2021-12-03 Harrison Zhu , Xing Liu , Ruya Kang , Zhichao Shen , Seth Flaxman , François-Xavier Briol

A multi-objective logistics optimization problem from a real-world supply chain is formulated as a Quadratic Unconstrained Binary Optimization Problem (QUBO) that minimizes cost, emissions, and delivery time, while maintaining target…

Optimization and Control · Mathematics 2026-02-06 Raoul Heese , Timothée Leleu , Sam Reifenstein , Christian Nietner , Yoshihisa Yamamoto

Quantum approaches to combinatorial optimization problems (COPs) are often limited by the resource demands of Quadratic Unconstrained Binary Optimization (QUBO) encodings, which enlarge circuits through penalty terms and increase qubit and…

Quantum Physics · Physics 2025-11-25 Frederik Koch , Shahram Panahiyan , Rick Mukherjee , Joseph Doetsch , Dieter Jaksch

This study proposes a novel method for simplifying inequality constraints in Higher-Order Binary Optimization (HOBO) formulations. The proposed method addresses challenges associated with Quadratic Unconstrained Binary Optimization (QUBO)…

Optimization and Control · Mathematics 2025-01-22 Yuichiro Minato

Quantum annealers provide an effective framework for solving large-scale combinatorial optimization problems. This work presents a novel methodology for training Variational Quantum Algorithms (VQAs) by reformulating the parameter…

Quantum Physics · Physics 2025-09-03 Ernesto Acosta , Guillermo Botella , Carlos Cano

There is a growing interest in harnessing the potential of the Rydberg-atom system to address complex combinatorial optimization challenges. Here we present an experimental demonstration of how the quadratic unconstrained binary…

Quantum Physics · Physics 2024-07-03 Andrew Byun , Junwoo Jung , Kangheun Kim , Minhyuk Kim , Seokho Jeong , Heejeong Jeong , Jaewook Ahn

Quantum and quantum-inspired optimisation algorithms are designed to solve problems represented in binary, quadratic and unconstrained form. Combinatorial optimisation problems are therefore often formulated as Quadratic Unconstrained…

Artificial Intelligence · Computer Science 2022-05-27 Mayowa Ayodele , Richard Allmendinger , Manuel López-Ibáñez , Matthieu Parizy

Annealing machines specialized for combinatorial optimization problems have been developed, and some companies offer services to use those machines. Such specialized machines can only handle binary variables, and their input format is the…

Quantum Physics · Physics 2023-03-24 Yuki Furue , Makiko Konoshima , Hirotaka Tamura , Jun Ohkubo

This paper presents a novel optimization approach for allocating grid operation costs in Peer-to-Peer (P2P) electricity markets using Quantum Computing (QC). We develop a Quadratic Unconstrained Binary Optimization (QUBO) model that matches…

A classical decision tree is completely based on splitting measures, which utilize the occurrence of random events in correspondence to its class labels in order to optimally segregate datasets. However, the splitting measures are based on…

Quantum Physics · Physics 2024-12-10 Diksha Sharma , Parvinder Singh , Atul Kumar
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