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Instrumental variable (IV) methods are central to causal inference from observational data, particularly when a randomized experiment is not feasible. However, of the three conventional core IV identification conditions, only one, IV…

Methodology · Statistics 2025-09-23 Zhonghua Liu , Baoluo Sun , Ting Ye , David Richardson , Eric Tchetgen Tchetgen

In this note, we offer an approach to estimating causal/structural parameters in the presence of many instruments and controls based on methods for estimating sparse high-dimensional models. We use these high-dimensional methods to select…

Applications · Statistics 2017-10-03 Victor Chernozhukov , Christian Hansen , Martin Spindler

Causal inference relies on two fundamental assumptions: ignorability and positivity. We study causal inference when the true confounder value can be expressed as a function of the observed data; we call this setting estimation with…

Methodology · Statistics 2021-02-18 Aahlad Puli , Adler J. Perotte , Rajesh Ranganath

We present a multi-fidelity method for uncertainty quantification of parameter estimates in complex systems, leveraging generative models trained to sample the target conditional distribution. In the Bayesian inference setting, traditional…

Machine Learning · Computer Science 2025-04-03 Caroline Tatsuoka , Minglei Yang , Dongbin Xiu , Guannan Zhang

The instrumental variable method consistently estimates the effect of a treatment when there is unmeasured confounding and a valid instrumental variable. A valid instrumental variable is a variable that is independent of unmeasured…

Methodology · Statistics 2016-02-03 Zijian Guo , Dylan Small

Causal inference across multiple data sources offers a promising avenue to enhance the generalizability and replicability of scientific findings. However, data integration methods for time-to-event outcomes, common in biomedical research,…

Methodology · Statistics 2025-05-16 Yi Liu , Alexander W. Levis , Ke Zhu , Shu Yang , Peter B. Gilbert , Larry Han

Interpretability is central for scientific machine learning, as understanding \emph{why} models make predictions enables hypothesis generation and validation. While tabular foundation models show strong performance, existing explanation…

Machine Learning · Computer Science 2026-04-01 Luan Borges Teodoro Reis Sena , Francisco Galuppo Azevedo

Probabilistic prediction aims to compute predictive distributions rather than single point predictions. These distributions enable practitioners to quantify uncertainty, compute risk, and detect outliers. However, most probabilistic methods…

Machine Learning · Computer Science 2024-10-23 Nicolas Beltran-Velez , Alessandro Antonio Grande , Achille Nazaret , Alp Kucukelbir , David Blei

In numerous predictive scenarios, the predictive model affects the sampling distribution; for example, job applicants often meticulously craft their resumes to navigate through a screening systems. Such shifts in distribution are…

Machine Learning · Statistics 2025-04-14 Daniele Bracale , Subha Maity , Moulinath Banerjee , Yuekai Sun

Instrumental variable methods provide a powerful approach to estimating causal effects in the presence of unobserved confounding. But a key challenge when applying them is the reliance on untestable "exclusion" assumptions that rule out any…

Methodology · Statistics 2020-06-23 Jason Hartford , Victor Veitch , Dhanya Sridhar , Kevin Leyton-Brown

Simulation-based inference methods that feature correct conditional coverage of confidence sets based on observations that have been compressed to a scalar test statistic require accurate modeling of either the p-value function or the…

Machine Learning · Statistics 2025-08-18 Ali Al Kadhim , Harrison B. Prosper

Small Earth data are geoscience observations with limited short-term monitoring variability, providing sparse but meaningful measurements, typically exhibiting spatiotemporal correlations. Spatiotemporal forecasting on such data is crucial…

Machine Learning · Computer Science 2025-10-13 Yuting Yang , Gang Mei , Zhengjing Ma , Nengxiong Xu , Jianbing Peng

Predicting counterfactual outcomes in longitudinal data, where sequential treatment decisions heavily depend on evolving patient states, is critical yet notoriously challenging due to complex time-dependent confounding and inadequate…

Machine Learning · Statistics 2026-04-15 Farbod Alinezhad , Jianfei Cao , Gary J. Young , Brady Post

Causal inference is the process of estimating the effect or impact of a treatment on an outcome with other covariates as potential confounders (and mediators) that may need to be controlled. The vast majority of existing methods and systems…

Computation and Language · Computer Science 2022-05-05 Arun S. Maiya

The fundamental problem of causal inference - that the counterfactual outcome for any individual is never observed - has shaped the entire methodology of the field. Every existing approach substitutes assumptions for missing data:…

Artificial Intelligence · Computer Science 2026-04-03 Olav Laudy

TabPFN has emerged as a promising in-context learning model for tabular data, capable of directly predicting the labels of test samples given labeled training examples. It has demonstrated competitive performance, particularly on…

Machine Learning · Computer Science 2025-02-05 Si-Yang Liu , Han-Jia Ye

A popular way to estimate the causal effect of a variable x on y from observational data is to use an instrumental variable (IV): a third variable z that affects y only through x. The more strongly z is associated with x, the more reliable…

Machine Learning · Computer Science 2020-04-14 Zhaobin Kuang , Frederic Sala , Nimit Sohoni , Sen Wu , Aldo Córdova-Palomera , Jared Dunnmon , James Priest , Christopher Ré

Learning-based methods for constructing control barrier functions (CBFs) are gaining popularity for ensuring safe robot control. A major limitation of existing methods is their reliance on extensive sampling over the state space or online…

Systems and Control · Electrical Eng. & Systems 2025-03-17 Hongzhan Yu , Seth Farrell , Ryo Yoshimitsu , Zhizhen Qin , Henrik I. Christensen , Sicun Gao

Near-infrared spectroscopy is increasingly used as a rapid, non-destructive chemical sensing technology for the analysis of food, pharmaceutical, biological, and environmental samples. However, the practical deployment of NIR sensors still…

Machine Learning · Computer Science 2026-05-22 Robin Reiter , Denis Cornet , Fabien Michel , Lauriane Rouan , Gregory Beurier

Unobserved confounding is the main obstacle to causal effect estimation from observational data. Instrumental variables (IVs) are widely used for causal effect estimation when there exist latent confounders. With the standard IV method,…

Artificial Intelligence · Computer Science 2023-12-12 Debo Cheng , Jiuyong Li , Lin Liu , Jiji Zhang , Thuc duy Le , Jixue Liu