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Related papers: BioResearcher: Scenario-Guided Multi-Agent for Tra…

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Current clinical agent built on small LLMs, such as TxAgent suffer from a \textit{Context Utilization Failure}, where models successfully retrieve biomedical evidence due to supervised finetuning but fail to ground their diagnosis in that…

Artificial Intelligence · Computer Science 2025-12-08 Ting-Ting Xie , Yixin Zhang

Identifying critical research within the growing body of academic work is an intrinsic aspect of conducting quality research. Systematic review processes used in evidence-based medicine formalise this as a procedure that must be followed in…

Digital Libraries · Computer Science 2024-10-14 John Hawkins , David Tivey

Given a user's complex information need, a multi-agent Deep Research system iteratively plans, retrieves, and synthesizes evidence across hundreds of documents to produce a high-quality answer. In one possible architecture, an orchestrator…

Information Retrieval · Computer Science 2026-04-06 Arthur Câmara , Vincent Slot , Jakub Zavrel

Scientific discovery relies on scientists generating novel hypotheses that undergo rigorous experimental validation. To augment this process, we introduce an AI co-scientist, a multi-agent system built on Gemini 2.0. The AI co-scientist is…

Large language models (LLMs) integrated with autonomous agents hold significant potential for advancing scientific discovery through automated reasoning and task execution. However, applying LLM agents to drug discovery is still constrained…

Artificial Intelligence · Computer Science 2025-07-29 Kun Li , Zhennan Wu , Shoupeng Wang , Jia Wu , Shirui Pan , Wenbin Hu

Small language models are attractive for production deployment due to their low cost, fast inference, and ease of specialization. However, adapting them to a specific task remains a challenging engineering loop, driven not by training…

Artificial Intelligence · Computer Science 2026-04-14 Dhruv Atreja , Julia White , Nikhil Nayak , Kelton Zhang , Henrijs Princis , George Hurn-Maloney , Ash Lewis , Urchade Zaratiana

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

Computation and Language · Computer Science 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

DeepResearch agents represent a transformative AI paradigm, conducting expert-level research through sophisticated reasoning and multi-tool integration. However, evaluating these systems remains critically challenging due to open-ended…

Artificial Intelligence · Computer Science 2025-10-10 Tianyu Fan , Xinyao Niu , Yuxiang Zheng , Fengji Zhang , Chengen Huang , Bei Chen , Junyang Lin , Chao Huang

Today's AI models learn primarily through mimicry and refining, so it is not surprising that they struggle to solve problems beyond the limits set by existing data. To solve novel problems, agents should acquire skills for exploring and…

Artificial Intelligence · Computer Science 2026-03-25 Raj Ghugare , Roger Creus Castanyer , Catherine Ji , Kathryn Wantlin , Jin Schofield , Karthik Narasimhan , Benjamin Eysenbach

The post-pandemic surge in healthcare demand, coupled with critical nursing shortages, has placed unprecedented pressure on medical triage systems, necessitating innovative AI-driven solutions. We present a multi-agent interactive…

Artificial Intelligence · Computer Science 2025-08-05 Hongyan Cheng , Chengzhang Yu , Yanshu Shi , Chiyue Wang , Cong Liu , Zhanpeng Jin

Agentic multimodal models have garnered significant attention for their ability to leverage external tools to tackle complex tasks. However, it is observed that such agents often meet premature interaction collapse, caused by two primary…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Shengqin Wang , Wentao Yan , Huichi Zhou , Yihang Chen , Kun Shao , Zhizhong Zhang , Yuan Xie

AI agent research spans a wide spectrum: from RL agents that learn from scratch to foundation model agents that leverage pre-trained knowledge, yet no unified benchmark enables fair comparison across these approaches. We present Agentick, a…

Artificial Intelligence · Computer Science 2026-05-14 Roger Creus Castanyer , Pablo Samuel Castro , Glen Berseth

Large language models are increasingly being assembled into medical multi-agent systems that emulate multidisciplinary consultation through specialist roles, peer review and consensus formation. In clinical decision support, however,…

Computation and Language · Computer Science 2026-05-28 Yinghao Zhu , Lei Gu , Zixiang Wang , Haoran Sang , Dehao Sui , Wen Tang , Lan Mi , Yasha Wang , Junyi Gao , Liang Yao , Tianfan Fu , Ewen Harrison , Lequan Yu , Liantao Ma

Biomedical queries often rely on a deep understanding of specialized knowledge such as gene regulatory mechanisms and pathological processes of diseases. They require detailed analysis of complex physiological processes and effective…

Computation and Language · Computer Science 2026-02-02 Congying Liu , Xingyuan Wei , Peipei Liu , Yiqing Shen , Yanxu Mao , Tiehan Cui

Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Artificial Intelligence · Computer Science 2025-05-23 Adib Bazgir , Amir Habibdoust Lafmajani , Yuwen Zhang

Scaling laws for inference compute in multi-agent systems remain under-explored compared to single-agent scenarios. This work aims to bridge this gap by investigating the problem of data synthesis through multi-agent sampling, where…

Computation and Language · Computer Science 2025-05-20 Hai Ye , Mingbao Lin , Hwee Tou Ng , Shuicheng Yan

Recent progress in large language models (LLMs) has enabled substantial advances in solving mathematical problems. However, existing benchmarks often fail to reflect the complexity of real-world problems, which demand open-ended,…

Artificial Intelligence · Computer Science 2025-05-22 Cheng Qian , Hongyi Du , Hongru Wang , Xiusi Chen , Yuji Zhang , Avirup Sil , Chengxiang Zhai , Kathleen McKeown , Heng Ji

Validating scientific hypotheses is a central challenge in biomedical research, and remains difficult for artificial intelligence (AI) agents due to the complexity of real-world data analysis and evidence interpretation. In this work, we…

Artificial Intelligence · Computer Science 2025-05-23 Zifeng Wang , Benjamin Danek , Jimeng Sun

Large language models (LLMs) have recently shown strong progress on scientific reasoning, yet two major bottlenecks remain. First, explicit retrieval fragments reasoning, imposing a hidden "tool tax" of extra tokens and steps. Second,…

Autonomous systems that generate scientific hypotheses, conduct experiments, and draft manuscripts have recently emerged as a promising paradigm for accelerating discovery. However, existing AI Scientists remain largely domain-agnostic,…

Artificial Intelligence · Computer Science 2026-03-31 Hongtao Wu , Boyun Zheng , Dingjie Song , Yu Jiang , Jianfeng Gao , Lei Xing , Lichao Sun , Yixuan Yuan