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A fundamental property of DNA is that the reverse complement (RC) of a sequence often carries identical biological meaning. However, state-of-the-art DNA language models frequently fail to capture this symmetry, producing inconsistent…

Machine Learning · Computer Science 2025-09-24 Mingqian Ma

Large language models (LLMs) show strong potential for neural architecture generation, yet existing approaches produce complete model implementations from scratch -- computationally expensive and yielding verbose code. We propose Delta-Code…

Machine Learning · Computer Science 2026-05-07 Santosh Premi Adhikari , Radu Timofte , Dmitry Ignatov

Large Language Models (LLMs) have significantly advanced artificial intelligence, excelling in numerous tasks. Although the functionality of a model is inherently tied to its parameters, a systematic method for exploring the connections…

Artificial Intelligence · Computer Science 2026-01-27 Yue Hu , Gang Hu , Jixin Zheng , Patrick X. Zhao , Ruimeng Wang

Multilingual transfer ability, which reflects how well models fine-tuned on one source language can be applied to other languages, has been well studied in multilingual pre-trained models. However, the existence of such capability transfer…

Computation and Language · Computer Science 2025-01-20 Wang Liang

Multi-view datasets offer diverse forms of data that can enhance prediction models by providing complementary information. However, the use of multi-view data leads to an increase in high-dimensional data, which poses significant challenges…

Neural and Evolutionary Computing · Computer Science 2024-03-05 Vandad Imani , Carlos Sevilla-Salcedo , Elaheh Moradi , Vittorio Fortino , Jussi Tohka

Despite a plethora of anomaly detection models developed over the years, their ability to generalize to unseen anomalies remains an issue, particularly in critical systems. This paper aims to address this challenge by introducing Swift…

Machine Learning · Statistics 2025-03-26 Nguyen Do , Truc Nguyen , Malik Hassanaly , Raed Alharbi , Jung Taek Seo , My T. Thai

Research on long non-coding RNAs (lncRNAs) has garnered significant attention due to their critical roles in gene regulation and disease mechanisms. However, the complexity and diversity of lncRNA sequences, along with the limited knowledge…

Genomics · Quantitative Biology 2024-11-07 Wei Wang , Zhichao Hou , Xiaorui Liu , Xinxia Peng

Existing methods for vision-and-language learning typically require designing task-specific architectures and objectives for each task. For example, a multi-label answer classifier for visual question answering, a region scorer for…

Computation and Language · Computer Science 2021-05-25 Jaemin Cho , Jie Lei , Hao Tan , Mohit Bansal

Modern language models scale depth by stacking layers, each holding its own state - a per-layer KV cache in transformers, a per-layer matrix in Mamba, Gated DeltaNet (GDN), RWKV, and xLSTM. Biological systems lean heavily on recurrence…

Computation and Language · Computer Science 2026-05-12 Zanmin Wang

The rapid advancement of DNA sequencing has produced vast genomic datasets, yet interpreting and engineering genomic function remain fundamental challenges. Recent large language models have opened new avenues for genomic analysis, but…

We propose a novel methodology to address dialog learning in the context of goal-oriented conversational systems. The key idea is to quantize the dialog space into clusters and create a language model across the clusters, thus allowing for…

Computation and Language · Computer Science 2018-12-27 R. Chulaka Gunasekara , David Nahamoo , Lazaros C. Polymenakos , Jatin Ganhotra , Kshitij P. Fadnis

Protein is linked to almost every life process. Therefore, analyzing the biological structure and property of protein sequences is critical to the exploration of life, as well as disease detection and drug discovery. Traditional protein…

Machine Learning · Computer Science 2021-12-08 Yijia Xiao , Jiezhong Qiu , Ziang Li , Chang-Yu Hsieh , Jie Tang

Projecting visual features into word embedding space has become a significant fusion strategy adopted by Multimodal Large Language Models (MLLMs). However, its internal mechanisms have yet to be explored. Inspired by multilingual research,…

Computation and Language · Computer Science 2025-05-21 Jiahao Huo , Yibo Yan , Boren Hu , Yutao Yue , Xuming Hu

The pre-dominant approach to language modeling to date is based on recurrent neural networks. Their success on this task is often linked to their ability to capture unbounded context. In this paper we develop a finite context approach…

Computation and Language · Computer Science 2017-09-12 Yann N. Dauphin , Angela Fan , Michael Auli , David Grangier

While many unsupervised learning models focus on one family of tasks, either generative or discriminative, we explore the possibility of a unified representation learner: a model which addresses both families of tasks simultaneously. We…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Soumik Mukhopadhyay , Matthew Gwilliam , Yosuke Yamaguchi , Vatsal Agarwal , Namitha Padmanabhan , Archana Swaminathan , Tianyi Zhou , Jun Ohya , Abhinav Shrivastava

Generative machine learning models offer a powerful framework for therapeutic design by efficiently exploring large spaces of biological sequences enriched for desirable properties. Unlike supervised learning methods, which require both…

Vision-language large models are moving toward the unification of visual understanding and visual generation tasks. However, whether generation can enhance understanding is still under-explored on large data scale. In this work, we analysis…

Computation and Language · Computer Science 2026-01-01 Fengjiao Chen , Minhao Jing , Weitao Lu , Yan Feng , Xiaoyu Li , Xuezhi Cao

Foundation models have received much attention due to their effectiveness across a broad range of downstream applications. Though there is a big convergence in terms of architecture, most pretrained models are typically still developed for…

Computation and Language · Computer Science 2022-06-14 Yaru Hao , Haoyu Song , Li Dong , Shaohan Huang , Zewen Chi , Wenhui Wang , Shuming Ma , Furu Wei

Recent advances in language models opened new opportunities to address complex schema matching tasks. Schema matching approaches have been proposed that demonstrate the usefulness of language models, but they have also uncovered important…

Databases · Computer Science 2025-06-18 Yurong Liu , Eduardo Pena , Aecio Santos , Eden Wu , Juliana Freire

We propose WirelessJEPA, a novel wireless foundation model (WFM) that uses the Joint Embedding Predictive Architecture (JEPA). WirelessJEPA learns general-purpose representations directly from real-world multi-antenna IQ data by predicting…

Signal Processing · Electrical Eng. & Systems 2026-01-29 Viet Chu , Omar Mashaal , Hatem Abou-Zeid