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We propose a novel spectral generative model for image synthesis that departs radically from the common variational, adversarial, and diffusion paradigms. In our approach, images, after being flattened into one-dimensional signals, are…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Andrew Kiruluta

DNA-based biodiversity surveys involve collecting physical samples from survey sites and assaying the contents in the laboratory to detect species via their diagnostic DNA sequences. DNA-based surveys are increasingly being adopted for…

The future development of an AI scientist, a tool that is capable of integrating a variety of experimental data and generating testable hypotheses, holds immense potential. So far, bespoke machine learning models have been created to…

Quantitative Methods · Quantitative Biology 2024-03-05 Tyler D. Ross , Ashwin Gopinath

Natural Language Processing enables computers to understand human language by analysing and classifying text efficiently with deep-level grammatical and semantic features. Existing models capture features by learning from large corpora with…

Computation and Language · Computer Science 2026-02-25 Azrin Sultana , Firoz Ahmed

We introduce a new method to tag Multiword Expressions (MWEs) using a linguistically interpretable language-independent deep learning architecture. We specifically target discontinuity, an under-explored aspect that poses a significant…

Computation and Language · Computer Science 2019-04-26 Omid Rohanian , Shiva Taslimipoor , Samaneh Kouchaki , Le An Ha , Ruslan Mitkov

Effective extraction and application of linguistic features are central to the enhancement of spoken Language IDentification (LID) performance. With the success of recent large models, such as GPT and Whisper, the potential to leverage such…

Computation and Language · Computer Science 2023-12-19 Peng Shen , Xuguang Lu , Hisashi Kawai

Many natural language inference (NLI) datasets contain biases that allow models to perform well by only using a biased subset of the input, without considering the remainder features. For instance, models are able to make a classification…

Computation and Language · Computer Science 2021-09-01 Dimion Asael , Zachary Ziegler , Yonatan Belinkov

Linguistic analysis of language models is one of the ways to explain and describe their reasoning, weaknesses, and limitations. In the probing part of the model interpretability research, studies concern individual languages as well as…

Computation and Language · Computer Science 2022-10-25 Oleg Serikov , Vitaly Protasov , Ekaterina Voloshina , Viktoria Knyazkova , Tatiana Shavrina

Genomic language models (gLMs) hold promise for generating novel, functional DNA sequences for synthetic biology. However, realizing this potential requires models to go beyond evolutionary plausibility and understand how DNA sequence…

Quantitative Methods · Quantitative Biology 2025-08-27 Shiyu Jiang , Xuyin Liu , Zitong Jerry Wang

We propose a probabilistic model for interpreting gene expression levels that are observed through single-cell RNA sequencing. In the model, each cell has a low-dimensional latent representation. Additional latent variables account for…

Machine Learning · Computer Science 2018-01-18 Romain Lopez , Jeffrey Regier , Michael Cole , Michael Jordan , Nir Yosef

The intricate relationship between genetic variation and human diseases has been a focal point of medical research, evidenced by the identification of risk genes regarding specific diseases. The advent of advanced genome sequencing…

Quantitative Methods · Quantitative Biology 2024-01-19 Jiayu Chang , Shiyu Wang , Chen Ling , Zhaohui Qin , Liang Zhao

The diagnostic performance of most of the deep learning models is greatly affected by the selection of model architecture and hyperparameters. Manual selection of model architecture is not feasible as training and evaluating the different…

Neural and Evolutionary Computing · Computer Science 2022-02-24 Arun K. Sharma , Nishchal K. Verma

We propose a novel convolutional architecture, named $gen$CNN, for word sequence prediction. Different from previous work on neural network-based language modeling and generation (e.g., RNN or LSTM), we choose not to greedily summarize the…

Computation and Language · Computer Science 2015-04-27 Mingxuan Wang , Zhengdong Lu , Hang Li , Wenbin Jiang , Qun Liu

We present a language model that combines a large parametric neural network (i.e., a transformer) with a non-parametric episodic memory component in an integrated architecture. Our model uses extended short-term context by caching local…

Computation and Language · Computer Science 2021-02-05 Dani Yogatama , Cyprien de Masson d'Autume , Lingpeng Kong

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

Language models have emerged as powerful predictors of the viability of biological sequences. During training these models learn the rules of the grammar obeyed by sequences of amino acids or nucleotides. Once trained, these models can take…

Machine Learning · Computer Science 2025-04-25 Pranav Kantroo , Günter P. Wagner , Benjamin B. Machta

In many classification problems, we want a classifier that is robust to a range of non-semantic transformations. For example, a human can identify a dog in a picture regardless of the orientation and pose in which it appears. There is…

Machine Learning · Computer Science 2021-12-20 Scott Mahan , Tim Doster , Henry Kvinge

Network science has become an essential interdisciplinary tool for understanding complex biological systems. However, because these systems undergo continuous, often stimulus-driven changes in both structure and function, traditional static…

Molecular Networks · Quantitative Biology 2025-05-19 Abir Khazaal , Fatemeh Vafaee

Foundation models have made significant strides in understanding the genomic language of DNA sequences. However, previous models typically adopt the tokenization methods designed for natural language, which are unsuitable for DNA sequences…

Genomics · Quantitative Biology 2024-12-19 Lifeng Qiao , Peng Ye , Yuchen Ren , Weiqiang Bai , Chaoqi Liang , Xinzhu Ma , Nanqing Dong , Wanli Ouyang

We present a deep hierarchical recurrent neural network for sequence tagging. Given a sequence of words, our model employs deep gated recurrent units on both character and word levels to encode morphology and context information, and…

Computation and Language · Computer Science 2016-08-10 Zhilin Yang , Ruslan Salakhutdinov , William Cohen
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