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Effective generation of novel hypotheses is instrumental to scientific progress. So far, researchers have been the main powerhouse behind hypothesis generation by painstaking data analysis and thinking (also known as the Eureka moment). In…

Artificial Intelligence · Computer Science 2024-12-20 Yangqiaoyu Zhou , Haokun Liu , Tejes Srivastava , Hongyuan Mei , Chenhao Tan

Large language models (LLMs) are increasingly used as agents that interact with users and with the world. To do so successfully, LLMs must construct representations of the world and form probabilistic beliefs about them. To provide…

Computation and Language · Computer Science 2026-01-16 Linlu Qiu , Fei Sha , Kelsey Allen , Yoon Kim , Tal Linzen , Sjoerd van Steenkiste

Hypothesis generation is a fundamental step in scientific discovery, yet it is increasingly challenged by information overload and disciplinary fragmentation. Recent advances in Large Language Models (LLMs) have sparked growing interest in…

Large language models (LLMs) have been proposed as alternatives to human experts for estimating unknown quantities with associated uncertainty, a process known as Bayesian elicitation. We test this by asking eleven LLMs to estimate…

Artificial Intelligence · Computer Science 2026-04-03 Luka Hobor , Mario Brcic , Mihael Kovac , Kristijan Poje

Large language models (LLMs) are revolutionizing every aspect of society. They are increasingly used in problem-solving tasks to substitute human assessment and reasoning. LLMs are trained on what humans write and are thus exposed to human…

Software Engineering · Computer Science 2025-10-14 Fengfei Sun , Ningke Li , Kailong Wang , Lorenz Goette

Large Language Models (LLMs) demonstrate strong few-shot generalization through in-context learning, yet their reasoning in dynamic and stochastic environments remains opaque. Prior studies mainly focus on static tasks and overlook the…

Artificial Intelligence · Computer Science 2025-12-23 Jensen Zhang , Jing Yang , Keze Wang

State of the art large language models (LLMs) have shown impressive performance on a variety of benchmark tasks and are increasingly used as components in larger applications, where LLM-based predictions serve as proxies for human…

Computation and Language · Computer Science 2024-06-14 Michael Franke , Polina Tsvilodub , Fausto Carcassi

The rapid growth of biomedical knowledge has outpaced our ability to efficiently extract insights and generate novel hypotheses. Large language models (LLMs) have emerged as a promising tool to revolutionize knowledge interaction and…

Computation and Language · Computer Science 2024-07-16 Biqing Qi , Kaiyan Zhang , Kai Tian , Haoxiang Li , Zhang-Ren Chen , Sihang Zeng , Ermo Hua , Hu Jinfang , Bowen Zhou

This paper presents a method to analyze the inference patterns used by Large Language Models (LLMs) for judgment in a case study on legal LLMs, so as to identify potential incorrect representations of the LLM, according to human domain…

Artificial Intelligence · Computer Science 2025-05-21 Lu Chen , Yuxuan Huang , Yixing Li , Dongrui Liu , Qihan Ren , Shuai Zhao , Kun Kuang , Zilong Zheng , Quanshi Zhang

We propose a hybrid approach to machine Theory of Mind (ToM) that uses large language models (LLMs) as a mechanism for generating hypotheses and likelihood functions with a Bayesian inverse planning model that computes posterior…

Artificial Intelligence · Computer Science 2025-07-08 Rebekah A. Gelpí , Eric Xue , William A. Cunningham

The widespread adoption of large language models (LLMs) makes it important to recognize their strengths and limitations. We argue that in order to develop a holistic understanding of these systems we need to consider the problem that they…

Computation and Language · Computer Science 2023-09-26 R. Thomas McCoy , Shunyu Yao , Dan Friedman , Matthew Hardy , Thomas L. Griffiths

Since the advent of Large Language Models (LLMs), efforts have largely focused on improving their instruction-following and deductive reasoning abilities, leaving open the question of whether these models can truly discover new knowledge.…

Computation and Language · Computer Science 2025-10-31 Kaiyu He , Zhiyu Chen

Autoregressive Large Language Models (LLMs) trained for next-word prediction have demonstrated remarkable proficiency at producing coherent text. But are they equally adept at forming coherent probability judgments? We use probabilistic…

Computation and Language · Computer Science 2025-05-07 Jian-Qiao Zhu , Thomas L. Griffiths

Large language models (LLMs) have been shown to acquire sequence-level planning abilities during training, yet their planning behavior exhibited at inference time often appears short-sighted and inconsistent with these capabilities. We…

Artificial Intelligence · Computer Science 2026-02-04 Haijiang Yan , Jian-Qiao Zhu , Adam Sanborn

Large Language Models (LLMs) are transforming scientific hypothesis generation and validation by enabling information synthesis, latent relationship discovery, and reasoning augmentation. This survey provides a structured overview of…

This paper investigates the capabilities of large language models (LLMs) in formulating and solving decision-making problems using mathematical programming. We first conduct a systematic review and meta-analysis of recent literature to…

Artificial Intelligence · Computer Science 2025-08-26 Mohammad J. Abdel-Rahman , Yasmeen Alslman , Dania Refai , Amro Saleh , Malik A. Abu Loha , Mohammad Yahya Hamed

Large Language Models (LLMs) show impressive inductive reasoning capabilities, enabling them to generate hypotheses that could generalize effectively to new instances when guided by in-context demonstrations. However, in real-world…

Artificial Intelligence · Computer Science 2024-12-19 Zhuo Liu , Ding Yu , Hangfeng He

Significant scientific discoveries have driven the progress of human civilisation. The explosion of scientific literature and data has created information barriers across disciplines that have slowed the pace of scientific discovery. Large…

Computation and Language · Computer Science 2023-11-13 Biqing Qi , Kaiyan Zhang , Haoxiang Li , Kai Tian , Sihang Zeng , Zhang-Ren Chen , Bowen Zhou

We compare human and large language model (LLM) generalization in the number game, a concept inference task. Using a Bayesian model as an analytical framework, we examined the inductive biases and inference strategies of humans and LLMs.…

Artificial Intelligence · Computer Science 2025-12-24 Arghavan Bazigaran , Hansem Sohn

Large Language Models (LLMs) possess general world knowledge but often struggle to generate precise predictions in structured, domain-specific contexts such as simulations. These limitations arise from their inability to ground their broad,…

Artificial Intelligence · Computer Science 2026-01-30 Guillaume Levy , Cedric Colas , Pierre-Yves Oudeyer , Thomas Carta , Clement Romac
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