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With the rapid advancement of Multi-modal Large Language Models (MLLMs), several diagnostic benchmarks have recently been developed to assess these models' multi-modal reasoning proficiency. However, these benchmarks are restricted to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Sanjoy Chowdhury , Sayan Nag , Subhrajyoti Dasgupta , Yaoting Wang , Mohamed Elhoseiny , Ruohan Gao , Dinesh Manocha

Longitudinal clinical reasoning over electronic health records requires tracking evolving physiological measurements, laboratory results, and interventions across extended patient trajectories. Existing LLM-based clinical reasoning systems…

Machine Learning · Computer Science 2026-05-27 Zhan Qu , Michael Färber

Pathological assessment guides lung cancer diagnosis, treatment selection, and prognostic evaluation, yet current CPath approaches rely on task-specific models for isolated objectives. Although pan-cancer foundation models offer…

Purpose: To utilize high-resolution quantitative CT (QCT) imaging features for prediction of diagnosis and prognosis in fibrosing interstitial lung diseases (ILD). Approach: 40 ILD patients (20 usual interstitial pneumonia (UIP), 20 non-UIP…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Babak Haghighi , Warren B. Gefter , Lauren Pantalone , Despina Kontos , Eduardo Mortani Barbosa

Recent progress in Large Vision-Language Models (LVLMs) has enabled promising applications in medical tasks, such as report generation and visual question answering. However, existing benchmarks focus mainly on the final diagnostic answer,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Hyungyung Lee , Geon Choi , Jung-Oh Lee , Hangyul Yoon , Hyuk Gi Hong , Edward Choi

Understanding and quantifying uncertainty in large language model (LLM) outputs is critical for reliable deployment. However, traditional evaluation approaches provide limited insight into model confidence at individual token positions…

Artificial Intelligence · Computer Science 2026-03-27 Farhan Ahmed , Yuya Jeremy Ong , Chad DeLuca

Automated lobar segmentation allows regional evaluation of lung disease and is important for diagnosis and therapy planning. Advanced statistical workflows permitting such evaluation is a needed area within respiratory medicine; their…

Image and Video Processing · Electrical Eng. & Systems 2021-05-12 Marc Boubnovski Martell , Mitchell Chen , Kristofer Linton-Reid , Joram M. Posma , Susan J Copley , Eric O. Aboagye

Medical Multi-modal Large Language Models (MLLMs) have shown promising clinical performance. However, their sensitivity to real-world input perturbations, such as imaging artifacts and textual errors, critically undermines their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Dunyuan XU , Xikai Yang , Yaoqian Li , Juzheng Miao , Jinpeng Li , Pheng-Ann Heng

Humans can imagine and manipulate visual images mentally, a capability known as spatial visualization. While many multi-modal benchmarks assess reasoning on visible visual information, the ability to infer unseen relationships through…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Siting Wang , Minnan Pei , Luoyang Sun , Cheng Deng , Yuchen Li , Kun Shao , Zheng Tian , Haifeng Zhang , Jun Wang

Large Language Models (LLMs) are increasingly capable of generating complete applications from natural language instructions, creating new opportunities in science and education. In these domains, interactive scientific demonstrations are…

Software Engineering · Computer Science 2026-05-21 Qiaosheng Chen , Yang Liu , Lei Li , Kai Chen , Qipeng Guo , Gong Cheng , Fei Yuan

Large language models (LLMs) have achieved significant success in interacting with human. However, recent studies have revealed that these models often suffer from hallucinations, leading to overly confident but incorrect judgments. This…

Computation and Language · Computer Science 2023-09-06 Yusheng Liao , Yutong Meng , Hongcheng Liu , Yanfeng Wang , Yu Wang

Background: Artificial intelligence (AI) assisted lung nodule detection systems are increasingly deployed in clinical settings without site-specific validation. Performance reported under benchmark conditions may not reflect real-world…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Daniel Soliman

As large language models (LLMs) are increasingly deployed in high-stakes and operational settings, evaluation strategies based solely on aggregate accuracy are often insucient to characterize system reliability. This study proposes a…

Artificial Intelligence · Computer Science 2026-05-06 Hikmat Karimov , Rahid Zahid Alekberli

Interpretability is essential in medical imaging to ensure that clinicians can comprehend and trust artificial intelligence models. In this paper, we propose a novel interpretable approach that combines attribute regularization of the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-15 Maxime Di Folco , Cosmin I. Bercea , Julia A. Schnabel

Room layout estimation predicts layouts from a single panorama. It requires datasets with large-scale and diverse room shapes to train the models. However, there are significant imbalances in real-world datasets including the dimensions of…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Taotao Jing , Lichen Wang , Naji Khosravan , Zhiqiang Wan , Zachary Bessinger , Zhengming Ding , Sing Bing Kang

Recently, histopathology vision-language foundation models (VLMs) have gained popularity due to their enhanced performance and generalizability across different downstream tasks. However, most existing histopathology benchmarks are either…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Roba Al Majzoub , Hashmat Malik , Muzammal Naseer , Zaigham Zaheer , Tariq Mahmood , Salman Khan , Fahad Khan

Recent benchmarks and datasets have been proposed to improve spatial reasoning in vision-language models (VLMs), yet existing open resources remain limited in scale, visual diversity, and instruction expressiveness. In this work, we…

Visual-Interleaved Chain-of-Thought (VI-CoT) enables Multi-modal Large Language Models (MLLMs) to continually update their understanding and decision space based on step-wise intermediate visual states (IVS), much like a human would, which…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Xuecheng Wu , Jiaxing Liu , Danlei Huang , Yifan Wang , Yunyun Shi , Kedi Chen , Junxiao Xue , Yang Liu , Chunlin Chen , Hairong Dong , Dingkang Yang

ivadomed is an open-source Python package for designing, end-to-end training, and evaluating deep learning models applied to medical imaging data. The package includes APIs, command-line tools, documentation, and tutorials. ivadomed also…

Image and Video Processing · Electrical Eng. & Systems 2020-10-26 Charley Gros , Andreanne Lemay , Olivier Vincent , Lucas Rouhier , Anthime Bucquet , Joseph Paul Cohen , Julien Cohen-Adad

Large foundation models are fundamentally transforming the software engineering landscape, demonstrating exceptional capabilities across diverse tasks such as code generation, debugging, and testing. Despite this rapid progress, a…

Software Engineering · Computer Science 2025-10-21 Shuzheng Gao , Eric John Li , Man Ho Lam , Jingyu Xiao , Yuxuan Wan , Chaozheng Wang , Ng Man Tik , Michael R. Lyu