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Deep neural networks (DNN) have been used successfully in many scientific problems for their high prediction accuracy, but their application to genetic studies remains challenging due to their poor interpretability. In this paper, we…

Machine Learning · Computer Science 2021-10-01 Peyman H. Kassani , Fred Lu , Yann Le Guen , Zihuai He

Advancements in deep learning are revolutionizing science and engineering. The immense success of deep learning is largely due to its ability to extract essential high-dimensional (HD) features from input data and make inference decisions…

Machine Learning · Computer Science 2025-01-30 Md Tauhidul Islam , Lei Xing

In this paper we describe the implementation of semi-structured deep distributional regression, a flexible framework to learn conditional distributions based on the combination of additive regression models and deep networks. Our…

Learning to sample from intractable distributions over discrete sets without relying on corresponding training data is a central problem in a wide range of fields, including Combinatorial Optimization. Currently, popular deep learning-based…

Machine Learning · Computer Science 2025-08-25 Sebastian Sanokowski , Sepp Hochreiter , Sebastian Lehner

We introduce variational spectral learning (VSL), a machine learning framework for solving partial differential equations (PDEs) that operates directly in the coefficient space of spectral expansions. VSL offers a principled bridge between…

Numerical Analysis · Mathematics 2026-01-07 M. M. Hammad

Deep neural networks are typically trained by uniformly sampling large datasets across epochs, despite evidence that not all samples contribute equally throughout learning. Recent work shows that progressively reducing the amount of…

Machine Learning · Computer Science 2026-04-15 Amar Gahir , Varshil Patel , Shreyank N Gowda

Residual-based adaptive strategies are widely used in scientific machine learning but remain largely heuristic. We introduce a unifying variational framework that formalizes these methods by integrating convex transformations of the…

Machine Learning · Computer Science 2025-09-29 Juan Diego Toscano , Daniel T. Chen , Vivek Oommen , Jérôme Darbon , George Em Karniadakis

Anomaly detection is a challenging problem in machine learning, and is even more so when dealing with instances that are captured in low-level, raw data representations without a well-behaved set of engineered features. The Radial Basis…

Machine Learning · Computer Science 2021-02-01 Mehran H. Z. Bazargani , Arjun Pakrashi , Brian Mac Namee

From fully connected neural networks to convolutional neural networks, the learned parameters within a neural network have been primarily relegated to the linear parameters (e.g., convolutional filters). The non-linear functions (e.g.,…

Neural and Evolutionary Computing · Computer Science 2019-11-22 Andrew Hryniowski , Alexander Wong

Representations of the world environment play a crucial role in artificial intelligence. It is often inefficient to conduct reasoning and inference directly in the space of raw sensory representations, such as pixel values of images.…

Machine Learning · Computer Science 2022-04-12 Kenji Kawaguchi , Linjun Zhang , Zhun Deng

In this work, we introduce kernels with random Fourier features in the meta-learning framework to leverage their strong few-shot learning ability. We propose meta variational random features (MetaVRF) to learn adaptive kernels for the…

Machine Learning · Computer Science 2020-08-14 Xiantong Zhen , Haoliang Sun , Yingjun Du , Jun Xu , Yilong Yin , Ling Shao , Cees Snoek

This paper develops variational continual learning (VCL), a simple but general framework for continual learning that fuses online variational inference (VI) and recent advances in Monte Carlo VI for neural networks. The framework can…

Machine Learning · Statistics 2018-05-22 Cuong V. Nguyen , Yingzhen Li , Thang D. Bui , Richard E. Turner

Deep learning models, including modern systems like large language models, are well known to offer unreliable estimates of the uncertainty of their decisions. In order to improve the quality of the confidence levels, also known as…

Machine Learning · Computer Science 2024-04-15 Jiayi Huang , Sangwoo Park , Osvaldo Simeone

The equations of complex dynamical systems may not be identified by expert knowledge, especially if the underlying mechanisms are unknown. Data-driven discovery methods address this challenge by inferring governing equations from…

Machine Learning · Computer Science 2026-02-05 Amit K. Chakraborty , Hao Wang , Pouria Ramazi

We introduce the Differentiable Weightless Neural Network (DWN), a model based on interconnected lookup tables. Training of DWNs is enabled by a novel Extended Finite Difference technique for approximate differentiation of binary values. We…

Signal processing, communications, and control have traditionally relied on classical statistical modeling techniques. Such model-based methods utilize mathematical formulations that represent the underlying physics, prior information and…

Signal Processing · Electrical Eng. & Systems 2022-09-13 Nir Shlezinger , Jay Whang , Yonina C. Eldar , Alexandros G. Dimakis

This paper proposes a deep neural network (DNN)-driven framework to address the longstanding generalization challenge in adaptive filtering (AF). In contrast to traditional AF frameworks that emphasize explicit cost function design, the…

Machine Learning · Statistics 2025-08-07 Qizhen Wang , Gang Wang , Ying-Chang Liang

Variational dimensionality reduction methods are widely used for their accuracy, generative capabilities, and robustness. We introduce a unifying framework that generalizes both such as traditional and state-of-the-art methods. The…

Machine Learning · Computer Science 2025-09-04 Eslam Abdelaleem , Ilya Nemenman , K. Michael Martini

Physics-governed models are increasingly paired with machine learning for accelerated predictions, yet most "physics--informed" formulations treat the governing equations as a penalty loss whose scale and meaning are set by heuristic…

Numerical Analysis · Mathematics 2026-04-14 Yuhe Wang , Min Wang

Invariance describes transformations that do not alter data's underlying semantics. Neural networks that preserve natural invariance capture good inductive biases and achieve superior performance. Hence, modern networks are handcrafted to…

Machine Learning · Computer Science 2023-09-18 Derek Xu , Yizhou Sun , Wei Wang