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Dendrograms are a way to represent evolutionary relationships between organisms. Nowadays, these are inferred based on the comparison of genes or protein sequences by taking into account their differences and similarities. The genetic…

Molecular Networks · Quantitative Biology 2019-09-09 Daniel Gamermann , Arnau Montagud , J. Alberto Conejero , Pedro Fernández de Córdoba , Javier F. Urchueguía

We propose an approach for improving sequence modeling based on autoregressive normalizing flows. Each autoregressive transform, acting across time, serves as a moving frame of reference, removing temporal correlations, and simplifying the…

Machine Learning · Computer Science 2022-03-09 Joseph Marino , Lei Chen , Jiawei He , Stephan Mandt

Reconstructing the tree of life from molecular sequences is a fundamental problem in computational biology. Modern data sets often contain a large number of genes, which can complicate the reconstruction problem due to the fact that…

Probability · Mathematics 2017-07-21 Constantinos Daskalakis , Sebastien Roch

Protein evolution through amino acid mutations is a cornerstone of life sciences. Recent advances in protein language models have shown rich evolutionary patterns, offering unprecedented potential for in-silicon directed evolution. However,…

Artificial Intelligence · Computer Science 2026-01-08 Yaodong Yang , Yang Wang , Jinpeng Li , Pei Guo , Da Han , Guangyong Chen , Pheng-Ann Heng

Visual autoregressive (VAR) models have recently emerged as a promising family of generative models, enabling a wide range of downstream vision tasks such as text-guided image editing. By shifting the editing paradigm from noise…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Tao Xia , Jiawei Liu , Yukun Zhang , Ting Liu , Wei Wang , Lei Zhang

Prior works have investigated the use of articulatory features as complementary representations for automatic speech recognition (ASR), but their use was largely confined to shallow acoustic models. In this work, we revisit articulatory…

Audio and Speech Processing · Electrical Eng. & Systems 2025-10-13 Ahmed Adel Attia , Jing Liu , Carol Espy Wilson

We present a new Markov chain Monte Carlo algorithm, implemented in software Arbores, for inferring the history of a sample of DNA sequences. Our principal innovation is a bridging procedure, previously applied only for simple stochastic…

Computation · Statistics 2019-03-06 Kari Heine , Alex Beskos , Ajay Jasra , David Balding , Maria De Iorio

Selecting input variables or design points for statistical models has been of great interest in adaptive design and active learning. Motivated by two scientific examples, this paper presents a strategy of selecting the design points for a…

Machine Learning · Statistics 2021-02-12 Chiwoo Park , Peihua Qiu , Jennifer Carpena-Núñez , Rahul Rao , Michael Susner , Benji Maruyama

Tree-structured LSTM is promising way to consider long-distance interaction over hierarchies. However, there have been few research efforts on the hyperparameter tuning of the construction and traversal of tree-structured LSTM. To name a…

Machine Learning · Computer Science 2020-08-24 Ruo Ando , Yoshiyasu Takefuji

Generative models using neural network have opened a door to large-scale studies for various application domains, especially for studies that suffer from lack of real samples to obtain statistically robust inference. Typically, these…

Computer Vision and Pattern Recognition · Computer Science 2018-12-12 Seong Jae Hwang , Zirui Tao , Won Hwa Kim , Vikas Singh

Deep reinforcement learning (DRL) is one promising approach to teaching robots to perform complex tasks. Because methods that directly reuse the stored experience data cannot follow the change of the environment in robotic problems with a…

Robotics · Computer Science 2022-01-26 Taisuke Kobayashi

Large language model (LLM)-based automatic speech recognition (ASR) has recently attracted a lot of attention due to its high recognition accuracy and enhanced multi-dialect support. However, the high decoding latency of LLMs challenges the…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-29 Linye Wei , Shuzhang Zhong , Songqiang Xu , Runsheng Wang , Ru Huang , Meng Li

In neural text editing, prevalent sequence-to-sequence based approaches directly map the unedited text either to the edited text or the editing operations, in which the performance is degraded by the limited source text encoding and long,…

Computation and Language · Computer Science 2021-03-30 Ning Shi , Ziheng Zeng , Haotian Zhang , Yichen Gong

While generative models have set new benchmarks for Target Speaker Extraction (TSE), their inherent reliance on global context precludes deployment in real-time applications. Direct adaptation to streaming scenarios often leads to…

We propose a model for evolution aiming to reproduce statistical features of fossil data, in particular the distributions of extinction events, the distribution of species per genus and the distribution of lifetimes, all of which are known…

Populations and Evolution · Quantitative Biology 2008-06-06 Peter Klimek , Stefan Thurner , Rudolf Hanel

We introduce a new paradigm for AutoRegressive (AR) image generation, termed Set AutoRegressive Modeling (SAR). SAR generalizes the conventional AR to the next-set setting, i.e., splitting the sequence into arbitrary sets containing…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Wenze Liu , Le Zhuo , Yi Xin , Sheng Xia , Peng Gao , Xiangyu Yue

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees relating species. Along branches, sequence evolution is modelled using a continuous-time Markov process characterised by an instantaneous rate…

The Multiple Sequence Alignment (MSA) is a computational abstraction that represents a partial summary either of indel history, or of structural similarity. Taking the former view (indel history), it is possible to use formal automata…

Populations and Evolution · Quantitative Biology 2015-06-04 Oscar Westesson , Gerton Lunter , Benedict Paten , Ian Holmes

We consider a multi-type Moran model (in continuous time) with selection and type-dependent mutation. This paper is concerned with the evolution of genealogical information forward in time. For this purpose we define and analytically…

Probability · Mathematics 2015-11-19 Peter Seidel

One of the fundamental principles of contemporary linguistics states that language processing requires the ability to extract recursively nested tree structures. However, it remains unclear whether and how this code could be implemented in…

Computation and Language · Computer Science 2021-01-08 Yair Lakretz , Théo Desbordes , Jean-Rémi King , Benoît Crabbé , Maxime Oquab , Stanislas Dehaene