Related papers: Tree-Conditioned Edit Flows for Ancestral Sequence…
Molecular phylogenetic techniques do not generally account for such common evolutionary events as site insertions and deletions (known as indels). Instead tree building algorithms and ancestral state inference procedures typically rely on…
The ancestral sequence reconstruction problem is the inference, back in time, of the properties of common sequence ancestors from measured properties of contemporary populations. Standard algorithms for this problem assume independent…
Automatic Speech Recognition (ASR) traditionally assumes known domains, but adding data from a new domain raises concerns about computational inefficiencies linked to retraining models on both existing and new domains. Fine-tuning solely on…
Ancestral sequence reconstruction is a key task in computational biology. It consists in inferring a molecular sequence at an ancestral species of a known phylogeny, given descendant sequences at the tip of the tree. In addition to its many…
Autoregressive generative models naturally generate variable-length sequences, while non-autoregressive models struggle, often imposing rigid, token-wise structures. We propose Edit Flows, a non-autoregressive model that overcomes these…
Recovering a tree that represents the evolutionary history of a group of species is a key task in phylogenetics. Performing this task using sequence data from multiple genetic markers poses two key challenges. The first is the discordance…
We establish necessary and sufficient conditions for consistent root reconstruction in continuous-time Markov models with countable state space on bounded-height trees. Here a root state estimator is said to be consistent if the probability…
We propose a monitoring mechanism for recording the evolution of systems after certain computations, maintaining the history in a tree-like structure. Technically, we develop the monitoring mechanism in a variant of ADR (after Architectural…
There is often a trade-off between performance and latency in streaming automatic speech recognition (ASR). Traditional methods such as look-ahead and chunk-based methods, usually require information from future frames to advance…
The complex correlation structure of a collection of orthologous DNA sequences is uniquely captured by the "ancestral recombination graph" (ARG), a complete record of coalescence and recombination events in the history of the sample.…
While most neural generative models generate outputs in a single pass, the human creative process is usually one of iterative building and refinement. Recent work has proposed models of editing processes, but these mostly focus on editing…
We introduce EvoFlows, a variable-length protein sequence-to-sequence modeling approach designed for protein engineering. Existing protein language models are poorly suited for optimization tasks: autoregressive models require full sequence…
An evolutionary tree is a cascade of bifurcations starting from a single common root, generating a growing set of daughter species as time goes by. Species here is a general denomination for biological species, spoken languages or any other…
Given natural limitations on the length DNA sequences, designing phylogenetic reconstruction methods which are reliable under limited information is a crucial endeavor. There have been two approaches to this problem: reconstructing partial…
Automatic Speech Recognition (ASR) is an integral component of modern technology, powering applications such as voice-activated assistants, transcription services, and accessibility tools. Yet ASR systems continue to struggle with the…
Error correction techniques have been used to refine the output sentences from automatic speech recognition (ASR) models and achieve a lower word error rate (WER) than original ASR outputs. Previous works usually use a sequence-to-sequence…
Neural network pruning offers an effective method for compressing a multilingual automatic speech recognition (ASR) model with minimal performance loss. However, it entails several rounds of pruning and re-training needed to be run for each…
This thesis presents Regenerative Rejection Sampling (RRS), a novel approximate sampling algorithm inspired by classical Rejection Sampling and Markov Chain Monte Carlo methods. The method constructs a continuous-time regenerative process…
Recent advances in flow-based generative models have enabled training-free, text-guided image editing by inverting an image into its latent noise and regenerating it under a new target conditional guidance. However, existing methods…
A method based on mapping a symbolic sequence into a set of patterns (strings resulting from the sequence parsing) is proposed as a tool for the reconstruction of ancestral sequences. The set union of patterns comprises all the patterns…