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Purpose: Artificial intelligence (AI), and in particular large language models (LLMs), are increasingly being explored as tools to support life cycle assessment (LCA). While demonstrations exist across environmental and social domains,…

Computation and Language · Computer Science 2025-10-24 Artur Donaldson , Bharathan Balaji , Cajetan Oriekezie , Manish Kumar , Laure Patouillard

Large Language Models (LLMs) have shown promise in various domains, including healthcare, with significant potential to transform mental health applications by enabling scalable and accessible solutions. This study aims to provide a…

Artificial Intelligence · Computer Science 2025-11-25 Abdelrahman Hanafi , Mohammed Saad , Noureldin Zahran , Radwa J. Hanafy , Mohammed E. Fouda

In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation. While structured physiological data provides quantitative insights, clinical notes offer unstructured,…

Computation and Language · Computer Science 2024-11-27 Harshavardhan Battula , Jiacheng Liu , Jaideep Srivastava

Storytelling is a powerful form of communication and may provide insights into factors contributing to gaps in healthcare outcomes. To determine whether Large Language Models (LLMs) can identify potential underlying factors and avenues for…

Computers and Society · Computer Science 2025-10-30 Maneesh Bilalpur , Megan Hamm , Young Ji Lee , Natasha Norman , Kathleen M. McTigue , Yanshan Wang

Large language models (LLMs) have demonstrated transformative potential in scientific research, yet their deployment in high-stakes contexts raises significant trustworthiness concerns. Here, we introduce SciTrust 2.0, a comprehensive…

Artificial Intelligence · Computer Science 2025-10-31 Emily Herron , Junqi Yin , Feiyi Wang

The rising prevalence of eye diseases poses a growing public health burden. Large language models (LLMs) offer a promising path to reduce documentation workload and support clinical decision-making. However, few have been tailored for…

The proliferation of Large Language Models (LLMs) has intensified concerns about manipulative or deceptive behaviors that can undermine user autonomy, trust, and well-being. Existing safety benchmarks predominantly rely on coarse binary…

Artificial Intelligence · Computer Science 2025-12-30 Sadia Asif , Israel Antonio Rosales Laguan , Haris Khan , Shumaila Asif , Muneeb Asif

As Large Language Models (LLMs) are increasingly integrated into healthcare to address complex inquiries, ensuring their reliability remains a critical challenge. Recent studies have highlighted that generic LLMs often struggle in clinical…

Computation and Language · Computer Science 2026-04-01 Bian Sun , Zhenjian Wang , Orvill de la Torre , Zirui Wang

Background: As large language models (LLMs) are increasingly used in healthcare and medical consultation settings, a growing concern is whether these models can respond to medical inquiries in a manner that is ethically…

Computers and Society · Computer Science 2026-02-02 Hanhui Xu , Jiacheng Ji , Haoan Jin , Han Ying , Mengyue Wu

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

Ensuring robust safety measures across a wide range of scenarios is crucial for user-facing systems. While Large Language Models (LLMs) can generate valuable data for safety measures, they often exhibit distributional biases, focusing on…

Computation and Language · Computer Science 2024-10-16 Sabit Hassan , Anthony Sicilia , Malihe Alikhani

Large Language Models (LLMs) are increasingly deployed for code generation in high-stakes software development, yet their limited transparency in security reasoning and brittleness to evolving vulnerability patterns raise critical…

Software Engineering · Computer Science 2026-03-03 Manisha Mukherjee , Vincent J. Hellendoorn

The proliferation of Large Language Models (LLMs) has demonstrated remarkable capabilities, elevating the critical importance of LLM safety. However, existing safety methods rely on ad-hoc taxonomy and lack a rigorous, systematic…

Computation and Language · Computer Science 2025-09-29 Wenbin Hu , Huihao Jing , Haochen Shi , Haoran Li , Yangqiu Song

Objective: Survival analysis is central to medical prediction, yet large language models (LLMs) are rarely used as end-to-end survival models because censoring prevents straightforward supervised fine-tuning. Here we present LLMSurvival, a…

Artificial Intelligence · Computer Science 2026-05-26 Yishu Wei , Hexin Dong , Yi Lin , Jiahe Qian , Yi Liu , Yifan Peng

The proliferation of Large Language Models (LLMs) and Intelligent Virtual Agents acting as psychotherapists presents significant opportunities for expanding mental healthcare access. However, their deployment has also been linked to serious…

Computation and Language · Computer Science 2025-09-23 Ian Steenstra , Timothy W. Bickmore

Inappropriate design and deployment of machine learning (ML) systems leads to negative downstream social and ethical impact -- described here as social and ethical risks -- for users, society and the environment. Despite the growing need to…

Human-Computer Interaction · Computer Science 2022-10-10 Shalaleh Rismani , Renee Shelby , Andrew Smart , Edgar Jatho , Joshua Kroll , AJung Moon , Negar Rostamzadeh

Large language models (LLMs) are increasingly used to support question answering and decision-making in high-stakes, domain-specific settings such as natural hazard response and infrastructure planning, where effective answers must convey…

Computation and Language · Computer Science 2026-02-11 Homaira Huda Shomee , Rochana Chaturvedi , Yangxinyu Xie , Tanwi Mallick

Large language model (LLM) benchmarks inform LLM use decisions (e.g., "is this LLM safe to deploy for my use case and context?"). However, benchmarks may be rendered unreliable by various failure modes that impact benchmark bias, variance,…

Large Language Models increasingly power critical infrastructure from healthcare to finance, yet their vulnerability to adversarial manipulation threatens system integrity and user safety. Despite growing deployment, no comprehensive…

Cryptography and Security · Computer Science 2026-03-19 Taiwo Onitiju , Iman Vakilinia

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic…

Computation and Language · Computer Science 2026-01-08 Lecheng Gong , Weimin Fang , Ting Yang , Dongjie Tao , Chunxiao Guo , Peng Wei , Bo Xie , Jinqun Guan , Zixiao Chen , Fang Shi , Jinjie Gu , Junwei Liu