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Multimodal image registration is a very challenging problem for deep learning approaches. Most current work focuses on either supervised learning that requires labelled training scans and may yield models that bias towards annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Mattias P Heinrich , Lasse Hansen

Both limited annotation and domain shift are prevalent challenges in medical image segmentation. Traditional semi-supervised segmentation and unsupervised domain adaptation methods address one of these issues separately. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Qinghe Ma , Jian Zhang , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao

Magnetic resonance images (MRIs) are widely used to quantify vestibular schwannoma and the cochlea. Recently, deep learning methods have shown state-of-the-art performance for segmenting these structures. However, training segmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Hao Li , Dewei Hu , Qibang Zhu , Kathleen E. Larson , Huahong Zhang , Ipek Oguz

Deep learning models for medical image segmentation often struggle when deployed across different datasets due to domain shifts - variations in both image appearance, known as style, and population-dependent anatomical characteristics,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Hoda Kalabizadeh , Ludovica Griffanti , Pak-Hei Yeung , Ana I. L. Namburete , Nicola K. Dinsdale , Konstantinos Kamnitsas

The recent prevalence of deep neural networks has lead semantic segmentation networks to achieve human-level performance in the medical field when sufficient training data is provided. Such networks however fail to generalize when tasked…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Serban Stan , Mohammad Rostami

Unsupervised cross-modality medical image adaptation aims to alleviate the severe domain gap between different imaging modalities without using the target domain label. A key in this campaign relies upon aligning the distributions of source…

Computer Vision and Pattern Recognition · Computer Science 2022-09-07 Zixian Su , Kai Yao , Xi Yang , Qiufeng Wang , Yuyao Yan , Jie Sun , Kaizhu Huang

The accuracy and robustness of image classification with supervised deep learning are dependent on the availability of large-scale, annotated training data. However, there is a paucity of annotated data available due to the complexity of…

Computer Vision and Pattern Recognition · Computer Science 2019-03-27 Euijoon Ahn , Ashnil Kumar , Dagan Feng , Michael Fulham , Jinman Kim

Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in practice: 1) only limited labeled samples are available due to expensive annotation costs over…

Machine Learning · Computer Science 2019-11-19 Yifan Zhang , Ying Wei , Peilin Zhao , Shuaicheng Niu , Qingyao Wu , Mingkui Tan , Junzhou Huang

Although achieving remarkable progress, it is very difficult to induce a supervised classifier without any labeled data. Unsupervised domain adaptation is able to overcome this challenge by transferring knowledge from a labeled source…

Machine Learning · Computer Science 2021-06-29 Yuntao Du , Ruiting Zhang , Xiaowen Zhang , Yirong Yao , Hengyang Lu , Chongjun Wang

Medical image analysis using supervised deep learning methods remains problematic because of the reliance of deep learning methods on large amounts of labelled training data. Although medical imaging data repositories continue to expand…

Computer Vision and Pattern Recognition · Computer Science 2019-06-11 Euijoon Ahn , Ashnil Kumar , Dagan Feng , Michael Fulham , Jinman Kim

Limited availability of annotated medical imaging data poses a challenge for deep learning algorithms. Although transfer learning minimizes this hurdle in general, knowledge transfer across disparate domains is shown to be less effective.…

Computer Vision and Pattern Recognition · Computer Science 2020-05-26 Jitender Singh Virk , Deepti R. Bathula

Annotating histopathological images is a time-consuming andlabor-intensive process, which requires broad-certificated pathologistscarefully examining large-scale whole-slide images from cells to tissues.Recent frontiers of transfer learning…

Computer Vision and Pattern Recognition · Computer Science 2020-08-24 Dou Xu , Chang Cai , Chaowei Fang , Bin Kong , Jihua Zhu , Zhongyu Li

Unsupervised domain adaptation is effective in leveraging the rich information from the source domain to the unsupervised target domain. Though deep learning and adversarial strategy make an important breakthrough in the adaptability of…

Machine Learning · Computer Science 2020-03-02 You-Wei Luo , Chuan-Xian Ren , Pengfei Ge , Ke-Kun Huang , Yu-Feng Yu

Domain shift, the mismatch between training and testing data characteristics, causes significant degradation in the predictive performance in multi-source imaging scenarios. In medical imaging, the heterogeneity of population, scanners and…

Machine Learning · Computer Science 2021-12-21 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Deep learning (DL) has shown remarkable success in various medical imaging data analysis applications. However, it remains challenging for DL models to achieve good generalization, especially when the training and testing datasets are…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Yuemeng Li , Yong Fan

Recently, we have witnessed great progress in the field of medical imaging classification by adopting deep neural networks. However, the recent advanced models still require accessing sufficiently large and representative datasets for…

Computer Vision and Pattern Recognition · Computer Science 2020-10-30 Haoliang Li , YuFei Wang , Renjie Wan , Shiqi Wang , Tie-Qiang Li , Alex C. Kot

The clinical integration of deep learning models for brain tumor diagnosis in neuro-oncology is severely constrained by limited expert-annotated MRI data and substantial inter-institutional domain shift arising from variations in scanners,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Sapna Sachan , Amulya Kumar Mahto , Prashant Wagambar Patil

Recent advances in deep learning-based medical image segmentation studies achieve nearly human-level performance in fully supervised manner. However, acquiring pixel-level expert annotations is extremely expensive and laborious in medical…

Computer Vision and Pattern Recognition · Computer Science 2023-05-19 Hyungseob Shin , Hyeongyu Kim , Sewon Kim , Yohan Jun , Taejoon Eo , Dosik Hwang

Medical image artificial intelligence models often achieve strong performance in single-center or single-device settings, yet their effectiveness frequently deteriorates in real-world cross-center deployment due to domain shift, limiting…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jingsong Xia , Siqi Wang

In mixed domain semi-supervised medical image segmentation (MiDSS), achieving superior performance under domain shift and limited annotations is challenging. This scenario presents two primary issues: (1) distributional differences between…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Bentao Song , Jun Huang , Qingfeng Wang