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Despite the recent advancements, conditional image generation still faces challenges of cost, generalizability, and the need for task-specific training. In this paper, we propose Manifold Preserving Guided Diffusion (MPGD), a training-free…

Ambiguity in medical image segmentation calls for models that capture full conditional distributions rather than a single point estimate. We present Prior-Guided Residual Diffusion (PGRD), a diffusion-based framework that learns voxel-wise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Fuyou Mao , Beining Wu , Yanfeng Jiang , Han Xue , Yan Tang , Hao Zhang

Classifier-free guidance (CFG) has become an essential component of modern diffusion models to enhance both generation quality and alignment with input conditions. However, CFG requires specific training procedures and is limited to…

Graphics · Computer Science 2025-11-06 Javad Rajabi , Soroush Mehraban , Seyedmorteza Sadat , Babak Taati

Diffusion models have been successful on a range of conditional generation tasks including molecular design and text-to-image generation. However, these achievements have primarily depended on task-specific conditional training or…

Machine Learning · Statistics 2024-11-26 Luhuan Wu , Brian L. Trippe , Christian A. Naesseth , David M. Blei , John P. Cunningham

Recently, diffusion probabilistic models have attracted attention in generative time series forecasting due to their remarkable capacity to generate high-fidelity samples. However, the effective utilization of their strong modeling ability…

Machine Learning · Computer Science 2024-03-19 Xinyao Fan , Yueying Wu , Chang Xu , Yuhao Huang , Weiqing Liu , Jiang Bian

Annealing-based neural samplers seek to amortize sampling from unnormalized distributions by training neural networks to transport a family of densities interpolating from source to target. A crucial design choice in the training phase of…

Machine Learning · Computer Science 2025-09-03 Ezra Erives , Bowen Jing , Peter Holderrieth , Tommi Jaakkola

Recent advances in diffusion-based generative models have shown incredible promise for zero shot image-to-image translation and editing. Most of these approaches work by combining or replacing network-specific features used in the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Zeqi Gu , Ethan Yang , Abe Davis

Recent research has focused on designing neural samplers that amortize the process of sampling from unnormalized densities. However, despite significant advancements, they still fall short of the state-of-the-art MCMC approach, Parallel…

Recent works have shown the potential of diffusion models in computer vision and natural language processing. Apart from the classical supervised learning fields, diffusion models have also shown strong competitiveness in reinforcement…

Machine Learning · Computer Science 2023-06-09 Jifeng Hu , Yanchao Sun , Sili Huang , SiYuan Guo , Hechang Chen , Li Shen , Lichao Sun , Yi Chang , Dacheng Tao

In the recent development of conditional diffusion models still require heavy supervised fine-tuning for performing control on a category of tasks. Training-free conditioning via guidance with off-the-shelf models is a favorable alternative…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Christian Simon , Masato Ishii , Akio Hayakawa , Zhi Zhong , Shusuke Takahashi , Takashi Shibuya , Yuki Mitsufuji

Adding additional control to pretrained diffusion models has become an increasingly popular research area, with extensive applications in computer vision, reinforcement learning, and AI for science. Recently, several studies have proposed…

Machine Learning · Computer Science 2024-05-30 Yifei Shen , Xinyang Jiang , Yezhen Wang , Yifan Yang , Dongqi Han , Dongsheng Li

Generating high-quality synthetic time series is a fundamental yet challenging task across domains such as forecasting and anomaly detection, where real data can be scarce, noisy, or costly to collect. Unlike static data generation,…

Machine Learning · Computer Science 2025-09-25 MohammadReza EskandariNasab , Shah Muhammad Hamdi , Soukaina Filali Boubrahimi

Given an unconditional diffusion model and a predictor for a target property of interest (e.g., a classifier), the goal of training-free guidance is to generate samples with desirable target properties without additional training. Existing…

Machine Learning · Computer Science 2024-11-20 Haotian Ye , Haowei Lin , Jiaqi Han , Minkai Xu , Sheng Liu , Yitao Liang , Jianzhu Ma , James Zou , Stefano Ermon

Generative models have the potential to accelerate key steps in the discovery of novel molecular therapeutics and materials. Diffusion models have recently emerged as a powerful approach, excelling at unconditional sample generation and,…

Biomolecules · Quantitative Biology 2024-07-17 Leo Klarner , Tim G. J. Rudner , Garrett M. Morris , Charlotte M. Deane , Yee Whye Teh

Discrete diffusion models are a class of generative models that construct sequences by progressively denoising samples from a categorical noise distribution. Beyond their rapidly growing ability to generate coherent natural language, these…

Computation and Language · Computer Science 2025-12-11 Michael Cardei , Jacob K Christopher , Thomas Hartvigsen , Bhavya Kailkhura , Ferdinando Fioretto

Diffusion models have recently gained prominence in offline reinforcement learning due to their ability to effectively learn high-performing, generalizable policies from static datasets. Diffusion-based planners facilitate long-horizon…

Machine Learning · Computer Science 2025-10-27 Donghyeon Ki , JunHyeok Oh , Seong-Woong Shim , Byung-Jun Lee

Diffusion models have achieved state-of-the-art performance in generative modeling tasks across various domains. Prior works on time series diffusion models have primarily focused on developing conditional models tailored to specific…

Machine Learning · Computer Science 2023-11-23 Marcel Kollovieh , Abdul Fatir Ansari , Michael Bohlke-Schneider , Jasper Zschiegner , Hao Wang , Yuyang Wang

Conventional class-guided diffusion models generally succeed in generating images with correct semantic content, but often struggle with texture details. This limitation stems from the usage of class priors, which only provide coarse and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Xiaoyu Yue , Zidong Wang , Zeyu Lu , Shuyang Sun , Meng Wei , Wanli Ouyang , Lei Bai , Luping Zhou

Neural networks are known to be susceptible to adversarial samples: small variations of natural examples crafted to deliberately mislead the models. While they can be easily generated using gradient-based techniques in digital and physical…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Haotian Xue , Alexandre Araujo , Bin Hu , Yongxin Chen

Dataset distillation compresses large datasets into compact synthetic ones to reduce storage and computational costs. Among various approaches, distribution matching (DM)-based methods have attracted attention for their high efficiency.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Fengli Ran , Xiao Pu , Bo Liu , Xiuli Bi , Bin Xiao
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