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The Bayesian analysis of infectious disease surveillance data from multiple locations typically involves building and fitting a spatio-temporal model of how the disease spreads in the structured population. Here we present new generally…

Methodology · Statistics 2025-03-04 Matthew Adeoye , Xavier Didelot , Simon EF Spencer

We introduce and analyze coupled, multi-strain epidemic models designed to simulate the emergence and dissemination of mutant (e.g. drug-resistant) pathogen strains. In particular, we investigate the mathematical and biological properties…

Populations and Evolution · Quantitative Biology 2017-05-10 Michael T. Meehan , Daniel G. Cocks , James M. Trauer , Emma S. McBryde

Tracking the spread of infectious disease during a pandemic has posed a great challenge to the governments and health sectors on a global scale. To facilitate informed public health decision-making, the concerned parties usually rely on…

Methodology · Statistics 2023-06-05 Tejasv Bedi , Yanxun Xu , Qiwei Li

Infectious diseases are caused by pathogenic microorganisms and can spread through different ways. Mathematical models and computational simulation have been used extensively to investigate the transmission and spread of infectious…

Infectious disease models can be of great use for understanding the underlying mechanisms that influence the spread of diseases and predicting future disease progression. Modeling has been increasingly used to evaluate the potential impact…

Applications · Statistics 2019-08-20 Md Mahsin , Rob Deardon , Patrick Brown

It is well recognised that animal and plant pathogens form complex ecological communities of interacting organisms within their hosts. Although community ecology approaches have been applied to determine pathogen interactions at the…

We present a contact-based model to study the spreading of epidemics by means of extending the dynamic message passing approach to temporal networks. The shift in perspective from node- to edge-centric quantities enables accurate modelling…

Physics and Society · Physics 2019-08-07 Andreas Koher , Hartmut H. K. Lentz , James P. Gleeson , Philipp Hövel

This paper presents a compact pairwise model that describes the spread of multi-stage epidemics on networks. The multi-stage model corresponds to a gamma-distributed infectious period which interpolates between the classical Markovian…

Populations and Evolution · Quantitative Biology 2016-12-08 N. Sherborne , K. B. Blyuss , I. Z. Kiss

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard…

Physics and Society · Physics 2015-11-23 N. Sherborne , K. B. Blyuss , I. Z. Kiss

In epidemiological disease mapping one aims to estimate the spatio-temporal pattern in disease risk and identify high-risk clusters, allowing health interventions to be appropriately targeted. Bayesian spatio-temporal models are used to…

Methodology · Statistics 2014-11-11 Duncan Lee , Andrew Lawson

The availability of geocoded health data and the inherent temporal structure of communicable diseases have led to an increased interest in statistical models and software for spatio-temporal data with epidemic features. The open source R…

Computation · Statistics 2017-05-12 Sebastian Meyer , Leonhard Held , Michael Höhle

We propose a new copula model for replicated multivariate spatial data. Unlike classical models that assume multivariate normality of the data, the proposed copula is based on the assumption that some factors exist that affect the joint…

Applications · Statistics 2018-10-12 Pavel Krupskii , Marc G. Genton

Copula-based models provide a great deal of flexibility in modelling multivariate distributions, allowing for the specifications of models for the marginal distributions separately from the dependence structure (copula) that links them to…

Methodology · Statistics 2021-09-09 Nicolás Kuschinski , Alejandro Jara

While most existing epidemic models focus on the influence of isolated factors, infectious disease transmission is inherently shaped by the complex interplay of multiple interacting elements. To better capture real-world dynamics, it is…

Physics and Society · Physics 2025-04-18 Guangyuan Mei , Yao Cai , Su-Su Zhang , Ying Huang , Chuang Liu , Xiu-Xiu Zhan

We present a computational modeling framework for data-driven simulations and analysis of infectious disease spread in large populations. For the purpose of efficient simulations, we devise a parallel solution algorithm targeting…

Populations and Evolution · Quantitative Biology 2018-02-19 Pavol Bauer , Stefan Engblom , Stefan Widgren

In this work we propose a novel space-dependent multiscale model for the spread of infectious diseases in a two-dimensional spatial context on realistic geographical scenarios. The model couples a system of kinetic transport equations…

Numerical Analysis · Mathematics 2020-12-21 Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi

Various data modalities are common in real-world applications (e.g., electronic health records, medical images and clinical notes in healthcare). It is essential to develop multimodal learning methods to aggregate various information from…

Machine Learning · Computer Science 2025-11-06 Feng Wu , Tsai Hor Chan , Fuying Wang , Guosheng Yin , Lequan Yu

Studying models of cyber epidemics over arbitrary complex networks can deepen our understanding of cyber security from a whole-system perspective. In this paper, we initiate the investigation of cyber epidemic models that accommodate the…

Cryptography and Security · Computer Science 2016-03-29 Maochao Xu , Gaofeng Da , Shouhuai Xu

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

Epidemic modeling is an essential tool to understand the spread of the novel coronavirus and ultimately assist in disease prevention, policymaking, and resource allocation. In this article, we establish a state of the art interface between…

Applications · Statistics 2020-12-17 Li Wang , Guannan Wang , Lei Gao , Xinyi Li , Shan Yu , Myungjin Kim , Yueying Wang , Zhiling Gu
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