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Large language models (LLMs) are increasingly being used in materials science. However, little attention has been given to benchmarking and standardized evaluation for LLM-based materials property prediction, which hinders progress. We…

Materials Science · Physics 2024-12-03 Andre Niyongabo Rubungo , Kangming Li , Jason Hattrick-Simpers , Adji Bousso Dieng

We demonstrate the ability of large language models (LLMs) to perform material and molecular property regression tasks, a significant deviation from the conventional LLM use case. We benchmark the Large Language Model Meta AI (LLaMA) 3 on…

Materials Science · Physics 2026-04-22 Ryan Jacobs , Maciej P. Polak , Lane E. Schultz , Hamed Mahdavi , Vasant Honavar , Dane Morgan

Scale is often attributed as one of the factors that cause an increase in the performance of LLMs, resulting in models with billion and trillion parameters. One of the limitations of such large models is the high computational requirements…

Machine Learning · Computer Science 2024-05-09 Sher Badshah , Hassan Sajjad

Metal-organic frameworks (MOFs) are porous crystalline materials with broad applications such as carbon capture and drug delivery, yet accurately predicting their 3D structures remains a significant challenge. While Large Language Models…

Machine Learning · Computer Science 2026-01-15 Mianzhi Pan , JianFei Li , Peishuo Liu , Botian Wang , Yawen Ouyang , Yiming Rong , Hao Zhou , Jianbing Zhang

Materials discovery and development are critical for addressing global challenges. Yet, the exponential growth in materials science literature comprising vast amounts of textual data has created significant bottlenecks in knowledge…

Machine learning has revolutionized polymer science by enabling rapid property prediction and generative design. Large language models (LLMs) offer further opportunities in polymer informatics by simplifying workflows that traditionally…

Computational Engineering, Finance, and Science · Computer Science 2026-02-20 Sonakshi Gupta , Akhlak Mahmood , Shivank Shukla , Rampi Ramprasad

This study introduces a systematic framework to compare the efficacy of Large Language Models (LLMs) for fine-tuning across various cheminformatics tasks. Employing a uniform training methodology, we assessed three well-known…

Machine Learning · Computer Science 2024-05-03 Lee Youngmin , Lang S. I. D. Andrew , Cai Duoduo , Wheat R. Stephen

Recent work has shown that scaling large language models (LLMs) improves their alignment with human brain activity, yet it remains unclear what drives these gains and which representational properties are responsible. Although larger models…

Large language models are increasingly deployed in settings where reliability matters, yet output-level uncertainty signals such as token probabilities, entropy, and self-consistency can become brittle under calibration--deployment…

Computation and Language · Computer Science 2026-04-20 Yanli Wang , Peng Kuang , Xiaoyu Han , Kaidi Xu , Haohan Wang

Contemporary large language models (LLMs), such as GPT-4 and Llama, have harnessed extensive computational power and diverse text corpora to achieve remarkable proficiency in interpreting and generating domain-specific content, including…

Machine Learning · Computer Science 2025-10-07 Tianren Zhang , Dai-Bei Yang

Despite their widespread use, large language models (LLMs) are known to hallucinate incorrect information and be poorly calibrated. This makes the uncertainty quantification of these models of critical importance, especially in high-stakes…

Machine Learning · Computer Science 2025-06-27 Colin Samplawski , Adam D. Cobb , Manoj Acharya , Ramneet Kaur , Susmit Jha

Predicting properties from coordinate-category data -- sets of vectors paired with categorical information -- is fundamental to computational science. In materials science, this challenge manifests as predicting properties like formation…

Materials Science · Physics 2025-07-10 Nawaf Alampara , Santiago Miret , Kevin Maik Jablonka

Large Language Models (LLMs) have shown promise in structured prediction tasks, including regression, but existing approaches primarily focus on point estimates and lack systematic comparison across different methods. We investigate…

Computation and Language · Computer Science 2025-06-10 Nikhita Vedula , Dushyanta Dhyani , Laleh Jalali , Boris Oreshkin , Mohsen Bayati , Shervin Malmasi

Large language models are increasingly applied to materials science, yet fundamental questions remain about their reliability and knowledge encoding. Evaluating 25 LLMs across four materials science tasks -- over 200 base and fine-tuned…

Materials Science · Physics 2026-03-03 Vineeth Venugopal , Soroush Mahjoubi , Elsa Olivetti

Accurate stock market predictions following earnings reports are crucial for investors. Traditional methods, particularly classical machine learning models, struggle with these predictions because they cannot effectively process and…

Computational Finance · Quantitative Finance 2024-11-13 Haowei Ni , Shuchen Meng , Xupeng Chen , Ziqing Zhao , Andi Chen , Panfeng Li , Shiyao Zhang , Qifu Yin , Yuanqing Wang , Yuxi Chan

Material selection is a crucial step in conceptual design due to its significant impact on the functionality, aesthetics, manufacturability, and sustainability impact of the final product. This study investigates the use of Large Language…

Computation and Language · Computer Science 2024-05-08 Daniele Grandi , Yash Patawari Jain , Allin Groom , Brandon Cramer , Christopher McComb

Predicting enzymatic reactions is crucial for applications in biocatalysis, metabolic engineering, and drug discovery, yet it remains a complex and resource-intensive task. Large Language Models (LLMs) have recently demonstrated remarkable…

Artificial Intelligence · Computer Science 2025-05-12 Lorenzo Di Fruscia , Jana Marie Weber

The integration of artificial intelligence into various domains is rapidly increasing, with Large Language Models (LLMs) becoming more prevalent in numerous applications. This work is included in an overall project which aims to train an…

Computational Physics · Physics 2025-01-09 Christophe Bajan , Guillaume Lambard

Estimating item difficulty through field-testing is often resource-intensive and time-consuming. As such, there is strong motivation to develop methods that can predict item difficulty at scale using only the item content. Large Language…

Computers and Society · Computer Science 2026-03-10 Pooya Razavi , Sonya Powers

Accessing the synthesizability of crystal structures is pivotal for advancing the practical application of theoretical material structures designed by machine learning or high-throughput screening. However, a significant gap exists between…

Materials Science · Physics 2024-07-10 Zhilong Song , Shuaihua Lu , Minggang Ju , Qionghua Zhou , Jinlan Wang
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