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Many models for the origin of life have focused on understanding how evolution can drive the refinement of a preexisting enzyme, such as the evolution of efficient replicase activity. Here we present a model for what was, arguably, an even…

Biomolecules · Quantitative Biology 2012-12-20 Sara Imari Walker , Martha A. Grover , Nicholas V. Hud

Life evolved on our planet by means of a combination of Darwinian selection and innovations leading to higher levels of complexity. The emergence and selection of replicating entities is a central problem in prebiotic evolution. Theoretical…

Adaptation and Self-Organizing Systems · Physics 2019-01-28 Jordi Piñero , Ricard Solé

This chapter is an overview of foundational results in the mathematical theory of replicator systems. Its primary aim is to provide a unified framework for the mathematical formalisation of evolutionary processes in the spirit of…

Populations and Evolution · Quantitative Biology 2026-04-08 A. S. Bratus , S. Drozhzhin , T. Yakushkina

While modern physics and biology satisfactorily explain the passage from the Big Bang to the formation of Earth and the first cells to present-day life, respectively, the origins of biochemical life still remain an open question. Since…

Populations and Evolution · Quantitative Biology 2025-02-25 Praful Gagrani , David Baum

Apparent biodiversity on earth exists only if we compare different species separated from their environments. Meanwhile coexisting species have to be identical in terms of energetic interactions. Consider the biosphere as a network of…

Populations and Evolution · Quantitative Biology 2007-05-23 D. Balciunas

An autocatalytic pattern matching polymer system is studied as an abstract model for chemical ecosystem evolution. Highly ordered populations with particular sequence patterns appear spontaneously out of a vast number of possible states.…

Molecular Networks · Quantitative Biology 2015-06-17 Shinpei Tanaka , Harold Fellermann , Steen Rasmussen

The now classical replicator equation describes a wide variety of biological phenomena, including those in theoretical genetics, evolutionary game theory, or in the theories of the origin of life. Among other questions, the permanence of…

Populations and Evolution · Quantitative Biology 2016-03-21 Alexander S. Bratus , Vladimir P. Posvyanskii , Artem S. Novozhilov

Template directed replication of nucleic acids is at the essence of all living beings and a major milestone for any origin of life scenario. We here present an idealized model of prebiotic sequence replication, where binary polymers act as…

Molecular Networks · Quantitative Biology 2017-12-20 Harold Fellermann , Shinpei Tanaka , Steen Rasmussen

The persistence of biodiversity of species is a challenging proposition in ecological communities in the face of Darwinian selection. The present article investigates beyond the pairwise competitive interactions and provides a novel…

Populations and Evolution · Quantitative Biology 2022-11-09 Sourin Chatterjee , Sayantan Nag Chowdhury , Dibakar Ghosh , Chittaranjan Hens

Living systems produce "persistent" copies of information-carrying polymers, in which template and copy sequences remain correlated after physically decoupling. We identify a general measure of the thermodynamic efficiency with which these…

Statistical Mechanics · Physics 2022-06-08 Jenny Poulton , Pieter Rein ten Wolde , Thomas E Ouldridge

Kingman's model describes the evolution of a one-locus haploid population of infinite size and discrete generations under the competition of selection and mutation. A random generalisation has been made in a previous paper which assumes all…

Probability · Mathematics 2020-12-01 Linglong Yuan

The evolution of complex cellular life involved two major transitions: the encapsulation of self-replicating genetic entities into cellular units and the aggregation of individual genes into a collectively replicating genome. In this paper,…

Populations and Evolution · Quantitative Biology 2021-09-21 Daniel B. Cooney , Fernando W. Rossine , Dylan H. Morris , Simon A. Levin

We investigate the evolutionary dynamics of an idealised model for the robust self-assembly of two-dimensional structures called polyominoes. The model includes rules that encode interactions between sets of square tiles that drive the…

Populations and Evolution · Quantitative Biology 2013-09-03 Iain G. Johnston , Sebastian A. Ahnert , Jonathan P. K. Doye , Ard A. Louis

Reduction of information entropy along with ever-increasing complexity are among the key signatures of living matter. Understanding the onset of such behavior in early prebiotic world is essential for solving the problem of origins of life.…

Populations and Evolution · Quantitative Biology 2018-10-17 Alexei V. Tkachenko , Sergei Maslov

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

Modern ecology has re-emphasized the need for a quantitative understanding of the original 'survival of the fittest theme' based on analyzis of the intricate trade-offs between competing evolutionary strategies that characterize the…

Populations and Evolution · Quantitative Biology 2015-06-16 Jacopo Grilli , Samir Suweis , Amos Maritan

Competitions can occur on an absolute scale, to be faster or more efficient, or they can occur on a relative scale, to "beat" one's competitor in a zero-sum game. Ecological models have focused on absolute competitions, in which optima…

Populations and Evolution · Quantitative Biology 2015-10-02 Joanna Masel

We study the evolution of recombination using a microscopic model developed within the frame of the theory of quantitative traits. Two components of fitness are considered: a static one that describes adaptation to environmental factors not…

Populations and Evolution · Quantitative Biology 2007-05-23 Franco Bagnoli , Carlo Guardiani

Dimerization and subsequent aggregation of polymers and biopolymers often occur under nonequilibrium conditions. When the initial state of the polymer is not collapsed or the final folded native state, the dynamics of dimerization can…

Soft Condensed Matter · Physics 2024-11-19 Sangita Mondal , Ved Mahajan , Biman Bagchi

Due to the conventional distinction between ecological (rapid) and evolutionary (slow)timescales, ecological and population models to date have typically ignored the effects of evolution. Yet the potential for rapid evolutionary change has…

Populations and Evolution · Quantitative Biology 2012-11-20 Laura E. Jones , Stephen P. Ellner
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