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Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

Training segmentation models for medical images continues to be challenging due to the limited availability of data annotations. Segment Anything Model (SAM) is a foundation model that is intended to segment user-defined objects of interest…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Maciej A. Mazurowski , Haoyu Dong , Hanxue Gu , Jichen Yang , Nicholas Konz , Yixin Zhang

This paper presents FeTal-SAM, a novel adaptation of the Segment Anything Model (SAM) tailored for fetal brain MRI segmentation. Traditional deep learning methods often require large annotated datasets for a fixed set of labels, making them…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Qi Zeng , Weide Liu , Bo Li , Ryne Didier , P. Ellen Grant , Davood Karimi

Foundation segmentation models such as SAM and SAM-2 perform well on natural images but struggle with brain MRIs where structures like the caudate and thalamus lack sharp boundaries and have low contrast. Rather than fine tune these models…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Keith Moore

Brain segmentation from neonatal MRI images is a very challenging task due to large changes in the shape of cerebral structures and variations in signal intensities reflecting the gestational process. In this context, there is a clear need…

Machine Learning · Statistics 2023-09-12 R Valabregue , F Girka , A Pron , F Rousseau , G Auzias

Whole-brain parcellation from MRI is a critical yet challenging task due to the complexity of subdividing the brain into numerous small, irregular shaped regions. Traditionally, template-registration methods were used, but recent advances…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Yucheng Li , Xiaofan Wang , Junyi Wang , Yijie Li , Xi Zhu , Mubai Du , Dian Sheng , Wei Zhang , Fan Zhang

Segmentation of brain structures on magnetic resonance imaging (MRI) is a highly relevant neuroimaging topic, as it is a prerequisite for different analyses such as volumetry or shape analysis. Automated segmentation facilitates the study…

Brain extraction and removal of skull artifacts from magnetic resonance images (MRI) is an important preprocessing step in neuroimaging analysis. There are many tools developed to handle human fMRI images, which could involve manual steps…

Image and Video Processing · Electrical Eng. & Systems 2024-01-11 Dwith Chenna , Suyash Bhogawar

Despite advances in data augmentation and transfer learning, convolutional neural networks (CNNs) difficultly generalise to unseen domains. When segmenting brain scans, CNNs are highly sensitive to changes in resolution and contrast: even…

Image and Video Processing · Electrical Eng. & Systems 2023-03-01 Benjamin Billot , Douglas N. Greve , Oula Puonti , Axel Thielscher , Koen Van Leemput , Bruce Fischl , Adrian V. Dalca , Juan Eugenio Iglesias

We present a deep learning strategy that enables, for the first time, contrast-agnostic semantic segmentation of completely unpreprocessed brain MRI scans, without requiring additional training or fine-tuning for new modalities. Classical…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Benjamin Billot , Douglas Greve , Koen Van Leemput , Bruce Fischl , Juan Eugenio Iglesias , Adrian V. Dalca

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

Reliable segmentation of anatomical tissues of human head is a major step in several clinical applications such as brain mapping, surgery planning and associated computational simulation studies. Segmentation is based on identifying…

Computer Vision and Pattern Recognition · Computer Science 2023-09-14 Essam A. Rashed , Mohammad al-Shatouri , Ilkka Laakso , Akimasa Hirata

In medical image segmentation, heterogeneous privacy policies across institutions often make joint training on pooled datasets infeasible, motivating continual image segmentation-learning from data streams without catastrophic forgetting.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Jiayi Wang , Wei Dai , Haoyu Wang , Sihan Yang , Haixia Bi , Jian Sun

Leveraging the Segment Anything Model (SAM) for medical image segmentation remains challenging due to its limited adaptability across diverse medical domains. Although fine-tuned variants, such as MedSAM, improve performance in scenarios…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Jianghao Wu , Yicheng Wu , Yutong Xie , Wenjia Bai , You Zhang , Feilong Tang , Yulong Li , Imran Razzak , Daniel F Schmidt , Yasmeen George

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

While the Segment Anything Model (SAM) excels in semantic segmentation for general-purpose images, its performance significantly deteriorates when applied to medical images, primarily attributable to insufficient representation of medical…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Yiming Zhang , Tianang Leng , Kun Han , Xiaohui Xie

Brain tumor segmentation presents a formidable challenge in the field of Medical Image Segmentation. While deep-learning models have been useful, human expert segmentation remains the most accurate method. The recently released Segment…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Mohammad Peivandi , Jason Zhang , Michael Lu , Dongxiao Zhu , Zhifeng Kou

Purpose: The goal of this work was to develop a deep network for whole-head segmentation including clinical MRIs with abnormal anatomy, and compile the first public benchmark dataset for this purpose. We collected 98 MRIs with volumetric…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Andrew M Birnbaum , Adam Buchwald , Peter Turkeltaub , Adam Jacks , George Carra , Shreya Kannana , Yu Huang , Abhisheck Datta , Lucas C Parra , Lukas A Hirsch

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

We present SAM4EM, a novel approach for 3D segmentation of complex neural structures in electron microscopy (EM) data by leveraging the Segment Anything Model (SAM) alongside advanced fine-tuning strategies. Our contributions include the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Uzair Shah , Marco Agus , Daniya Boges , Vanessa Chiappini , Mahmood Alzubaidi , Jens Schneider , Markus Hadwiger , Pierre J. Magistretti , Mowafa Househ , Corrado Calı
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