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Artificial intelligence (AI) is vital in ophthalmology, tackling tasks like diagnosis, classification, and visual question answering (VQA). However, existing AI models in this domain often require extensive annotation and are task-specific,…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Danli Shi , Weiyi Zhang , Xiaolan Chen , Yexin Liu , Jiancheng Yang , Siyu Huang , Yih Chung Tham , Yingfeng Zheng , Mingguang He

Visual impairment represents a major global health challenge, with multimodal imaging providing complementary information that is essential for accurate ophthalmic diagnosis. This comprehensive survey systematically reviews the latest…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Xiaoling Luo , Ruli Zheng , Qiaojian Zheng , Zibo Du , Shuo Yang , Meidan Ding , Qihao Xu , Chengliang Liu , Linlin Shen

Artificial intelligence (AI) has become a fundamental tool for assisting clinicians in analyzing ophthalmic images, such as optical coherence tomography (OCT). However, developing AI models often requires extensive annotation, and existing…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 José Morano , Botond Fazekas , Emese Sükei , Ronald Fecso , Taha Emre , Markus Gumpinger , Georg Faustmann , Marzieh Oghbaie , Ursula Schmidt-Erfurth , Hrvoje Bogunović

In oncology, Positron Emission Tomography-Computed Tomography (PET/CT) is widely used in cancer diagnosis, staging, and treatment monitoring, as it combines anatomical details from CT with functional metabolic activity and molecular marker…

This work explores the effectiveness of masked image modelling for learning representations of retinal OCT images. To this end, we leverage Masked Autoencoders (MAE), a simple and scalable method for self-supervised learning, to obtain a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Theodoros Pissas , Pablo Márquez-Neila , Sebastian Wolf , Martin Zinkernagel , Raphael Sznitman

Musculoskeletal disorders represent a leading cause of global disability, creating an urgent demand for precise interpretation of medical imaging. Current artificial intelligence (AI) approaches in orthopedics predominantly rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Kang Yu , Dingyu Wang , Zimu Yuan , Nan Zhou , Jiajun Liu , Jiaxin Liu , Shanggui Liu , Yaoyan Zheng , Huishu Yuan , Di Huang , Dong Jiang

The integration of AI-assisted biomedical image analysis into clinical practice demands AI-generated findings that are not only accurate but also interpretable to clinicians. However, existing biomedical AI models generally lack the ability…

We present VisionFM, a foundation model pre-trained with 3.4 million ophthalmic images from 560,457 individuals, covering a broad range of ophthalmic diseases, modalities, imaging devices, and demography. After pre-training, VisionFM…

We present OCTCube-M, a 3D OCT-based multi-modal foundation model for jointly analyzing OCT and en face images. OCTCube-M first developed OCTCube, a 3D foundation model pre-trained on 26,685 3D OCT volumes encompassing 1.62 million 2D OCT…

Image and Video Processing · Electrical Eng. & Systems 2024-12-20 Zixuan Liu , Hanwen Xu , Addie Woicik , Linda G. Shapiro , Marian Blazes , Yue Wu , Verena Steffen , Catherine Cukras , Cecilia S. Lee , Miao Zhang , Aaron Y. Lee , Sheng Wang

Artificial Intelligence (AI) has the potential to revolutionize diagnosis and segmentation in medical imaging. However, development and clinical implementation face multiple challenges including limited data availability, lack of…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Zelong Liu , Andrew Tieu , Nikhil Patel , Georgios Soultanidis , Louisa Deyer , Ying Wang , Sean Huver , Alexander Zhou , Yunhao Mei , Zahi A. Fayad , Timothy Deyer , Xueyan Mei

Inability to express the confidence level and detect unseen classes has limited the clinical implementation of artificial intelligence in the real-world. We developed a foundation model with uncertainty estimation (FMUE) to detect 11…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Yuanyuan Peng , Aidi Lin , Meng Wang , Tian Lin , Ke Zou , Yinglin Cheng , Tingkun Shi , Xulong Liao , Lixia Feng , Zhen Liang , Xinjian Chen , Huazhu Fu , Haoyu Chen

Vision-threatening eye diseases pose a major global health burden, with timely diagnosis limited by workforce shortages and restricted access to specialized care. While multimodal large language models (MLLMs) show promise for medical image…

Artificial intelligence has shown promise in medical imaging, yet most existing systems lack flexibility, interpretability, and adaptability - challenges especially pronounced in ophthalmology, where diverse imaging modalities are…

Artificial intelligence (AI) that can effectively learn ultrasound representations by integrating multi-source data holds significant promise for advancing clinical care. However, the scarcity of large labeled datasets in real-world…

In magnetically confined fusion device, the complex, multiscale, and nonlinear dynamics of plasmas necessitate the integration of extensive diagnostic systems to effectively monitor and control plasma behaviour. The complexity and…

Medical imaging is critical for diagnostics, but clinical adoption of advanced AI-driven imaging faces challenges due to patient variability, image artifacts, and limited model generalization. While deep learning has transformed image…

Image and Video Processing · Electrical Eng. & Systems 2025-06-02 Abdul-mojeed Olabisi Ilyas , Adeleke Maradesa , Jamal Banzi , Jianpan Huang , Henry K. F. Mak , Kannie W. Y. Chan

Optical coherence tomography angiography (OCTA) provides non-invasive visualization of retinal microvasculature, but learning robust representations remains challenging due to sparse vessel structures and strong topological constraints.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Ilerioluwakiiye Abolade , Prince Mireku , Kelechi Chibundu , Peace Ododo , Emmanuel Idoko , Promise Omoigui , Solomon Odelola

Missing input sequences are common in medical imaging data, posing a challenge for deep learning models reliant on complete input data. In this work, inspired by MultiMAE [2], we develop a masked autoencoder (MAE) paradigm for multi-modal,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Ayhan Can Erdur , Christian Beischl , Daniel Scholz , Jiazhen Pan , Benedikt Wiestler , Daniel Rueckert , Jan C Peeken

Multimodal large language models (MLLMs) have recently demonstrated remarkable reasoning abilities with reinforcement learning paradigm. Although several multimodal reasoning models have been explored in the medical domain, most of them…

Artificial Intelligence · Computer Science 2025-09-11 Ruiqi Wu , Yuang Yao , Tengfei Ma , Chenran Zhang , Na Su , Tao Zhou , Geng Chen , Wen Fan , Yi Zhou

The prevalence of vision-threatening eye diseases is a significant global burden, with many cases remaining undiagnosed or diagnosed too late for effective treatment. Large vision-language models (LVLMs) have the potential to assist in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Zhenyue Qin , Yu Yin , Dylan Campbell , Xuansheng Wu , Ke Zou , Yih-Chung Tham , Ninghao Liu , Xiuzhen Zhang , Qingyu Chen
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