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Understanding patterns of selectively neutral genetic variation is essential in order to model deviations from neutrality, caused for example by different forms of selection. Best understood is neutral genetic variation at a single locus,…

Populations and Evolution · Quantitative Biology 2012-06-13 E. Schaper , A. Eriksson , M. Rafajlovic , S. Sagitov , B. Mehlig

The genetic diversity of a species is shaped by its recent evolutionary history and can be used to infer demographic events or selective sweeps. Most inference methods are based on the null hypothesis that natural selection is a weak or…

Populations and Evolution · Quantitative Biology 2013-03-05 Richard A. Neher , Oskar Hallatschek

We consider the set of random Bienaym\'e-Galton-Watson trees with a bounded number of offspring and bounded number of generations as a statistical mechanics model: a random tree is a rooted subtree of the maximal tree; the spin at a given…

Mathematical Physics · Physics 2022-10-26 Francois Dunlop , Arif Mardin

We exhibit a stochastic discrete time model that has exactly the Eigen model as its deterministic continuous limit. Such model can be divided into two phases: reproduction followed by neutral selection. This result suggests that Eigen model…

Populations and Evolution · Quantitative Biology 2011-02-03 Fabio Musso

Consider a system $X = ((x_\xi(t)), \xi \in \Omega_N)_{t \geq 0}$ of interacting Fleming-Viot diffusions with mutation and selection which is a strong Markov process with continuous paths and state space $(\CP(\I))^{\Omega_N}$, where $\I$…

Probability · Mathematics 2011-04-07 Donald A. Dawson , Andreas Greven

Evolutionary game dynamics describes the spreading of successful strategies in a population of reproducing individuals. Typically, the microscopic definition of strategy spreading is stochastic, such that the dynamics becomes deterministic…

Populations and Evolution · Quantitative Biology 2015-05-13 Philipp M. Altrock , Arne Traulsen

Kingman's coalescent is one of the most popular models in population genetics. It describes the genealogy of a population whose genetic composition evolves in time according to the Wright-Fisher model, or suitable approximations of it…

Methodology · Statistics 2018-04-20 Stefano Favaro , Shui Feng , Paul A. Jenkins

Wright-Fisher diffusions describe the evolution of the type composition of an infinite haploid population with two types (say type $0$ and type $1$) subject to neutral reproductions, and possibly selection and mutations. In the present…

Probability · Mathematics 2022-12-21 Grégoire Véchambre

Widely used models in genetics include the Wright-Fisher diffusion and its moment dual, Kingman's coalescent. Each has a multilocus extension but under neither extension is the sampling distribution available in closed-form, and their…

Probability · Mathematics 2015-06-24 Paul A. Jenkins , Paul Fearnhead , Yun S. Song

We study two types of stochastic processes, a mean-field spatial system of interacting Fisher-Wright diffusions with an inferior and an advantageous type with rare mutation (inferior to advantageous) and a (mean-field) spatial system of…

Probability · Mathematics 2010-08-02 Donald A. Dawson , Andreas Greven

We consider a population model where individuals behave independently from each other and whose genealogy is described by a chronological tree called splitting tree. The individuals have i.i.d. (non-exponential) lifetime durations and give…

Probability · Mathematics 2014-05-20 Mathieu Richard

Joint distribution function of N eigenvalues of U(N) invariant random-matrix ensemble can be interpreted as a probability density to find N fictitious non-interacting fermions to be confined in a one-dimensional space. Within this picture a…

Condensed Matter · Physics 2017-02-08 E. Kanzieper , V. Freilikher

We consider a stochastic model describing a constant size $N$ population that may be seen as a directed polymer in random medium with $N$ sites in the transverse direction. The population dynamics is governed by a noisy traveling wave…

Probability · Mathematics 2016-06-07 Aser Cortines

We study fixation probabilities and times as a consequence of neutral genetic drift in subdivided populations, motivated by a model of the cultural evolutionary process of language change that is described by the same mathematics as the…

Populations and Evolution · Quantitative Biology 2015-05-26 R A Blythe

The recent explosion in available genetic data has led to significant advances in understanding the demographic histories of and relationships among human populations. It is still a challenge, however, to infer reliable parameter values for…

Populations and Evolution · Quantitative Biology 2013-04-09 Mark Lipson , Po-Ru Loh , Alex Levin , David Reich , Nick Patterson , Bonnie Berger

The two-phase sampling design is a cost-efficient way of collecting expensive covariate information on a judiciously selected subsample. It is natural to apply such a strategy for collecting genetic data in a subsample enriched for exposure…

Applications · Statistics 2013-05-27 Jaeil Ahn , Bhramar Mukherjee , Stephen B. Gruber , Malay Ghosh

The parameters of many classes of birth-death processes cannot be inferred uniquely from phylogenetic trees: infinitely many parameter combinations yield the same distribution of phylogenetic trees. Here, we show that parameter…

Populations and Evolution · Quantitative Biology 2026-04-21 Tobias Dieselhorst , Tanja Stadler

We introduce Flux Matching, a new paradigm for generative modeling that generalizes existing score-based models to a broader family of vector fields that need not be conservative. Rather than requiring the model to equal the data score, the…

Machine Learning · Computer Science 2026-05-11 Peter Pao-Huang , Xiaojie Qiu , Stefano Ermon

We develop a game theoretical model of $N$ heterogeneous interacting agents called the intelligent minority game. The ``intelligent'' agents play the basic minority game and depending on their performances, generate new strategies using the…

Statistical Mechanics · Physics 2009-11-07 Marko Sysi-Aho , Anirban Chakraborti , Kimmo Kaski

We review the statistical properties of the genealogies of a few models of evolution. In the asexual case, selection leads to coalescence times which grow logarithmically with the size of the population in contrast with the linear growth of…

Populations and Evolution · Quantitative Biology 2015-06-04 Éric Brunet , Bernard Derrida