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Drafting radiology reports is a complex task requiring flexibility, where radiologists tail content to available information and particular clinical demands. However, most current radiology report generation (RRG) models are constrained to…

In large population-based studies and in clinical routine, tasks like disease diagnosis and progression prediction are inherently based on a rich set of multi-modal data, including imaging and other sensor data, clinical scores, phenotypes,…

Integrating multi-omics data, such as DNA methylation, mRNA expression, and microRNA (miRNA) expression, offers a comprehensive view of the biological mechanisms underlying disease. However, the high dimensionality of multi-omics data, the…

In clinical practice, human radiologists actually review medical images with high resolution monitors and zoom into region of interests (ROIs) for a close-up examination. Inspired by this observation, we propose a hierarchical graph neural…

Real-world heterogeneous graphs are inherently noisy and usually not in the optimal graph structures for downstream tasks, which often adversely affects the performance of GRL models in downstream tasks. Although Graph Structure Learning…

Generating medical reports for X-ray images presents a significant challenge, particularly in unpaired scenarios where access to paired image-report data for training is unavailable. Previous works have typically learned a joint embedding…

Deep generative models have significantly advanced medical imaging analysis by enhancing dataset size and quality. Beyond mere data augmentation, our research in this paper highlights an additional, significant capacity of deep generative…

Medical imaging is widely used in clinical practice for diagnosis and treatment. Report-writing can be error-prone for unexperienced physicians, and time- consuming and tedious for experienced physicians. To address these issues, we study…

Graphs are a powerful tool for representing and analyzing unstructured, non-Euclidean data ubiquitous in the healthcare domain. Two prominent examples are molecule property prediction and brain connectome analysis. Importantly, recent works…

Integrating multi-omics datasets through data-driven analysis offers a comprehensive understanding of the complex biological processes underlying various diseases, particularly cancer. Graph Neural Networks (GNNs) have recently demonstrated…

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Large Language Models (LLMs) often suffer from hallucinations, which Retrieval-Augmented Generation (RAG) and GraphRAG mitigate by incorporating external knowledge and knowledge graphs (KGs). However, GraphRAG remains text-centric due to…

Knowledge Graphs (KGs) have proven highly effective for recommendation systems by capturing latent item relationships, while recent integration of Large Language Models (LLMs) has further enhanced semantic understanding and addressed…

Network topology excels at structural predictions but fails to capture functional semantics encoded in biomedical literature. We present RAG-GNN, an end-to-end trainable retrieval-augmented graph neural network framework that integrates GNN…

Medical Dialogue Generation serves a critical role in telemedicine by facilitating the dissemination of medical expertise to patients. Existing studies focus on incorporating textual representations, which have limited their ability to…

In the field of multimodal medical data analysis, leveraging diverse types of data and understanding their hidden relationships continues to be a research focus. The main challenges lie in effectively modeling the complex interactions…

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

The automatic generation of radiology reports given medical radiographs has significant potential to operationally and improve clinical patient care. A number of prior works have focused on this problem, employing advanced methods from…

Graph Retrieval-Augmented Generation (GraphRAG) enhances factual reasoning in LLMs by structurally modeling knowledge through graph-based representations. However, existing GraphRAG approaches face two core limitations: shallow retrieval…

Radiologists are tasked with interpreting a large number of images in a daily base, with the responsibility of generating corresponding reports. This demanding workload elevates the risk of human error, potentially leading to treatment…