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The rapid evolution of Large Language Models (LLMs) has shifted focus from general-purpose capabilities to domain-specific expertise. However, adapting LLMs to specialized fields such as medicine presents two challenge: (1) the…

Machine Learning · Computer Science 2026-01-14 Yuxin Yang , Aoxiong Zeng , Xiangquan Yang

In recent advancements, multimodal large language models (MLLMs) have been fine-tuned on specific medical image datasets to address medical visual question answering (Med-VQA) tasks. However, this common approach of task-specific…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Lai Wei , Wenkai Wang , Xiaoyu Shen , Yu Xie , Zhihao Fan , Xiaojin Zhang , Zhongyu Wei , Wei Chen

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Computation and Language · Computer Science 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

We evaluate four state-of-the-art instruction-tuned large language models (LLMs) -- ChatGPT, Flan-T5 UL2, Tk-Instruct, and Alpaca -- on a set of 13 real-world clinical and biomedical natural language processing (NLP) tasks in English, such…

Computation and Language · Computer Science 2024-06-11 Yanis Labrak , Mickael Rouvier , Richard Dufour

Free-text crash narratives recorded in real-world crash databases have been shown to play a significant role in improving traffic safety. However, large-scale analyses remain difficult to implement as there are no documented tools that can…

Computation and Language · Computer Science 2025-10-13 Xixi Wang , Jordanka Kovaceva , Miguel Costa , Shuai Wang , Francisco Camara Pereira , Robert Thomson

While Large Language Models (LLMs) have achieved strong performance on general-purpose language tasks, their deployment in regulated and data-sensitive domains, including insurance, remains limited. Leveraging millions of historical…

Computation and Language · Computer Science 2026-02-20 Zhengda Mo , Zhiyu Quan , Eli O'Donohue , Kaiwen Zhong

Neural Networks (NNs) trained through supervised learning struggle with managing edge-case scenarios common in real-world driving due to the intractability of exhaustive datasets covering all edge-cases, making knowledge-driven approaches,…

Artificial Intelligence · Computer Science 2025-04-17 Nicolas Baumann , Cheng Hu , Paviththiren Sivasothilingam , Haotong Qin , Lei Xie , Michele Magno , Luca Benini

While Large Language Models (LLMs) demonstrate significant potential in providing accessible mental health support, their practical deployment raises critical trustworthiness concerns due to the domains high-stakes and safety-sensitive…

Computation and Language · Computer Science 2026-03-04 Zixin Xiong , Ziteng Wang , Haotian Fan , Xinjie Zhang , Wenxuan Wang

This study presents an innovative approach to the application of large language models (LLMs) in clinical decision-making, focusing on OpenAI's ChatGPT. Our approach introduces the use of contextual prompts-strategically designed to include…

Artificial Intelligence · Computer Science 2023-08-22 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia

We present a framework for training large language models (LLMs) as diagnostic agents with reinforcement learning, enabling them to manage multi-turn interactive diagnostic processes, adaptively select examinations, and commit to final…

Computation and Language · Computer Science 2026-02-11 Pengcheng Qiu , Chaoyi Wu , Junwei Liu , Qiaoyu Zheng , Yusheng Liao , Haowen Wang , Yun Yue , Qianrui Fan , Shuai Zhen , Jian Wang , Jinjie Gu , Yanfeng Wang , Ya Zhang , Weidi Xie

Accuracy-based evaluation of Large Language Models (LLMs) measures benchmark-specific performance rather than underlying medical competency: it treats all questions as equally informative, conflates model ability with item characteristics,…

Computation and Language · Computer Science 2026-04-07 Zhimeng Luo , Lixin Wu , Adam Frisch , Daqing He

Domain specific large language models are increasingly used to support patient education, triage, and clinical decision making in ophthalmology, making rigorous evaluation essential to ensure safety and accuracy. This study evaluated four…

Multilingual large language models (LLMs) are known to more frequently generate non-faithful output in resource-constrained languages (Guerreiro et al., 2023 - arXiv:2303.16104), potentially because these typologically diverse languages are…

Computation and Language · Computer Science 2025-03-11 Tsan Tsai Chan , Xin Tong , Thi Thu Uyen Hoang , Barbare Tepnadze , Wojciech Stempniak

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the…

Instruction tuning is a pivotal technique for aligning large language models (LLMs) with human intentions, safety constraints, and domain-specific requirements. This survey provides a comprehensive overview of the full pipeline,…

Computation and Language · Computer Science 2025-11-20 Xudong Han , Junjie Yang , Tianyang Wang , Ziqian Bi , Xinyuan Song , Junfeng Hao , Junhao Song

Inaccuracies in existing or generated clinical text may lead to serious adverse consequences, especially if it is a misdiagnosis or incorrect treatment suggestion. With Large Language Models (LLMs) increasingly being used across diverse…

Computation and Language · Computer Science 2026-02-06 Congbo Ma , Yichun Zhang , Yousef Al-Jazzazi , Ahamed Foisal , Laasya Sharma , Yousra Sadqi , Khaled Saleh , Jihad Mallat , Farah E. Shamout

There is a significant gap between patient needs and available mental health support today. In this paper, we aim to thoroughly examine the potential of using Large Language Models (LLMs) to assist professional psychotherapy. To this end,…

Computation and Language · Computer Science 2025-01-28 Mian Zhang , Xianjun Yang , Xinlu Zhang , Travis Labrum , Jamie C. Chiu , Shaun M. Eack , Fei Fang , William Yang Wang , Zhiyu Zoey Chen

In modern industry, dynamic environments and the complexity of modular and reconfigurable resources require automated planning of process sequences. Capability-based planning approaches address this by automatically generating plans from…

Artificial Intelligence · Computer Science 2026-05-28 Luis Miguel Vieira da Silva , Nicolas König , Felix Gehlhoff

Multilingual large language models (LLMs) are increasingly deployed in linguistically diverse regions like India, yet most interpretability tools remain tailored to English. Prior work reveals that LLMs often operate in English centric…

Computation and Language · Computer Science 2026-02-19 Mihir Panchal , Deeksha Varshney , Mamta , Asif Ekbal

Reading comprehension is a key for individual success, yet the assessment of question difficulty remains challenging due to the extensive human annotation and large-scale testing required by traditional methods such as linguistic analysis…

Computation and Language · Computer Science 2025-02-26 Yoshee Jain , John Hollander , Amber He , Sunny Tang , Liang Zhang , John Sabatini
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