Related papers: GeoSAE: Geometric Prior-Guided Layer-Wise Sparse A…

Understanding the internal machinations of deep Transformer-based NLP models is more crucial than ever as these models see widespread use in various domains that affect the public at large, such as industry, academia, finance, health. While…

Transformer models have become state-of-the-art in decoding stimuli and behavior from neural activity, significantly advancing neuroscience research. Yet greater transparency in their decision-making processes would substantially enhance…

Sparse Autoencoders (SAEs) have recently emerged as powerful tools for interpreting and steering the internal representations of large language models (LLMs). However, conventional approaches to analyzing SAEs typically rely solely on…

Interpretability can improve the safety, transparency and trust of AI models, which is especially important in healthcare applications where decisions often carry significant consequences. Mechanistic interpretability, particularly through…

Concept unlearning in diffusion models is hampered by feature splitting, where concepts are distributed across many latent features, making their removal challenging and computationally expensive. We introduce SAEmnesia, a supervised sparse…

Current sparse autoencoder (SAE) approaches to neural network interpretability assume that activations can be decomposed through linear superposition into sparse, interpretable features. Despite high reconstruction fidelity, SAEs…

Alzheimer's disease (AD) is a major neurodegenerative condition that affects millions around the world. As one of the main biomarkers in the AD diagnosis procedure, brain amyloid positivity is typically identified by positron emission…

Self-supervised learning methods based on image patch reconstruction have witnessed great success in training auto-encoders, whose pre-trained weights can be transferred to fine-tune other downstream tasks of image understanding. However,…

Sparse autoencoders (SAEs) have emerged as a promising approach for learning interpretable features from neural network activations. However, the optimization landscape for SAE training can be challenging due to correlations in the input…

Sparse Autoencoders (SAEs) have emerged as a powerful unsupervised method for extracting sparse representations from language models, yet scalable training remains a significant challenge. We introduce a suite of 256 SAEs, trained on each…

Sparse autoencoders (SAEs) are a promising technique for decomposing language model activations into interpretable linear features. However, current SAEs fall short of completely explaining model performance, resulting in "dark matter":…

Histopathology images are crucial to the study of complex diseases such as cancer. The histologic characteristics of nuclei play a key role in disease diagnosis, prognosis and analysis. In this work, we propose a sparse Convolutional…

Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

Behavioral phenotyping of genetic animal models currently requires labor-intensive manual feature engineering that limits reproducibility and scalability. We present GEESE, an end-to-end deep learning framework that learns behavioral…

A key challenge in interpretability is to decompose model activations into meaningful features. Sparse autoencoders (SAEs) have emerged as a promising tool for this task. However, a central problem in evaluating the quality of SAEs is the…

Bioinformatics tools have been developed to interpret gene expression data at the gene set level, and these gene set based analyses improve the biologists' capability to discover functional relevance of their experiment design. While…

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Sparse autoencoders (SAEs) offer a natural path toward comparable explanations across different representation spaces. However, current SAEs are trained per modality, producing dictionaries whose features are not directly understandable and…

Sparse autoencoders (SAEs) are now standard tools for decomposing language model activations into interpretable features, and automated interpretability pipelines routinely assign each feature a short natural-language explanation. Existing…