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Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Using Large Language Models (LLMs) for relevance assessments offers promising opportunities to improve Information Retrieval (IR), Natural Language Processing (NLP), and related fields. Indeed, LLMs hold the promise of allowing IR…

Existing benchmarks for evaluating the clinical reasoning capabilities of large language models (LLMs) often lack a clear definition of "clinical reasoning" as a construct, fail to capture the full breadth of interdependent tasks within a…

The growing integration of Large Language Models (LLMs) into critical societal domains has raised concerns about embedded biases that can perpetuate stereotypes and undermine fairness. Such biases may stem from historical inequalities in…

Computation and Language · Computer Science 2025-10-17 Riccardo Cantini , Alessio Orsino , Massimo Ruggiero , Domenico Talia

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Evaluating natural language generation (NLG) systems in the medical domain presents unique challenges due to the critical demands for accuracy, relevance, and domain-specific expertise. Traditional automatic evaluation metrics, such as…

Computation and Language · Computer Science 2025-09-17 Wen-wai Yim , Asma Ben Abacha , Zixuan Yu , Robert Doerning , Fei Xia , Meliha Yetisgen

In recent years, Large Language Models (LLMs) have become widely used in medical applications, such as clinical decision support, medical education, and medical question answering. Yet, these models are often English-centric, limiting their…

Computation and Language · Computer Science 2026-02-06 Chaimae Abouzahir , Congbo Ma , Nizar Habash , Farah E. Shamout

Large Language Models (LLMs) have recently achieved impressive performance in math and reasoning benchmarks. However, they often struggle with logic problems and puzzles that are relatively easy for humans. To further investigate this, we…

Artificial Intelligence · Computer Science 2025-09-16 Nasim Borazjanizadeh , Roei Herzig , Trevor Darrell , Rogerio Feris , Leonid Karlinsky

Medical problem-solving demands expert knowledge and intricate reasoning. Recent studies of large language models (LLMs) attempt to ease this complexity by introducing external knowledge verification through retrieval-augmented generation…

Computation and Language · Computer Science 2026-01-19 Yue Huang , Yanyuan Chen , Dexuan Xu , Chenzhuo Zhao , Weihua Yue , Yu Huang

Automatic medication mining from clinical and biomedical text has become a popular topic due to its real impact on healthcare applications and the recent development of powerful language models (LMs). However, fully-automatic extraction…

Computation and Language · Computer Science 2023-08-09 Haifa Alrdahi , Lifeng Han , Hendrik Šuvalov , Goran Nenadic

Large language models (LLMs) are increasingly utilized in healthcare applications. However, their deployment in clinical practice raises significant safety concerns, including the potential spread of harmful information. This study…

Cryptography and Security · Computer Science 2025-03-05 Hang Zhang , Qian Lou , Yanshan Wang

This study introduces a benchmark framework for evaluating the financial decision-making capabilities of large language models (LLMs) through portfolio optimization problems with mathematically explicit solutions. Unlike existing financial…

Portfolio Management · Quantitative Finance 2026-05-28 Hanyong Cho , Jang Ho Kim

Recent advancements in Large Language Models (LLMs) and Large Vision Language Models (LVLMs) have enabled general-purpose systems to demonstrate promising capabilities in complex reasoning tasks, including those in the medical domain.…

Computation and Language · Computer Science 2026-05-19 Rafid Ahmed , Intesar Tahmid , Mir Sazzat Hossain , Tasnimul Hossain Tomal , Md Fahim , Md Farhad Alam Bhuiyan

Large language models (LLMs) are gaining increasing popularity in software engineering (SE) due to their unprecedented performance across various applications. These models are increasingly being utilized for a range of SE tasks, including…

Software Engineering · Computer Science 2025-11-05 Xing Hu , Feifei Niu , Junkai Chen , Xin Zhou , Junwei Zhang , Junda He , Xin Xia , David Lo

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

If AI models can detect when they are being evaluated, the effectiveness of evaluations might be compromised. For example, models could have systematically different behavior during evaluations, leading to less reliable benchmarks for…

Computation and Language · Computer Science 2025-07-17 Joe Needham , Giles Edkins , Govind Pimpale , Henning Bartsch , Marius Hobbhahn

The recent success of Large Language Models (LLMs) has had a significant impact on the healthcare field, providing patients with medical advice, diagnostic information, and more. However, due to a lack of professional medical knowledge,…

Computation and Language · Computer Science 2024-06-27 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Xiang Wan , Feng Jiang , Benyou Wang

Evaluating medical AI systems using expert clinician panels is costly and slow, motivating the use of large language models (LLMs) as alternative adjudicators. Here, we evaluate an LLM jury composed of three frontier AI models scoring 3333…

Integrating language models (LMs) in healthcare systems holds great promise for improving medical workflows and decision-making. However, a critical barrier to their real-world adoption is the lack of reliable evaluation of their…

Computation and Language · Computer Science 2025-12-15 Akash Ghosh , Srivarshinee Sridhar , Raghav Kaushik Ravi , Muhsin Muhsin , Sriparna Saha , Chirag Agarwal

Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex,…

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