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The Multi-Objective Real-Valued Gene-pool Optimal Mixing Evolutionary Algorithm (MO-RV-GOMEA) has been proven effective and efficient in solving real-world problems. A prime example is optimizing treatment plans for prostate cancer…

Neural and Evolutionary Computing · Computer Science 2022-03-18 Leah R. M. Dickhoff , Ellen M. Kerkhof , Heloisa H. Deuzeman , Carien L. Creutzberg , Tanja Alderliesten , Peter A. N. Bosman

A tunable stiffness bone rod was designed, optimized, and 3D printed to address the common shortcomings of existing bone rods in the healing of long fractured bones. The common deficiencies of existing bone fixations are high stiffness,…

Applied Physics · Physics 2025-07-25 Mohammad Saber Hashemi , Karl H. Kraus , Azadeh Sheidae

Deformable image registration is a critical technology in medical image analysis, with broad applications in clinical practice such as disease diagnosis, multi-modal fusion, and surgical navigation. Traditional methods often rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Zhengyong Huang , Xingwen Sun , Xuting Chang , Ning Jiang , Yao Wang , Jianfei Sun , Hongbin Han , Yao Sui

We propose and demonstrate a joint model of anatomical shapes, image features and clinical indicators for statistical shape modeling and medical image analysis. The key idea is to employ a copula model to separate the joint dependency…

Image and Video Processing · Electrical Eng. & Systems 2019-09-10 Bernhard Egger , Markus D. Schirmer , Florian Dubost , Marco J. Nardin , Natalia S. Rost , Polina Golland

One of the goals of computer-aided surgery is to match intraoperative data to preoperative images of the anatomy and add complementary information that can facilitate the task of surgical navigation. In this context, mechanical palpation…

Robotics · Computer Science 2015-09-22 Elif Ayvali , Rangaprasad Arun Srivatsan , Long Wang , Rajarshi Roy , Nabil Simaan , Howie Choset

Purpose. NTCP modelling is rapidly embracing DL methods as the need to include spatial dose information is acknowledged. Finding the most appropriate way of combining radiation dose distribution images and clinical data involves technical…

Medical Physics · Physics 2023-10-11 Laia Humbert-Vidan , Vinod Patel , Andrew P King , Teresa Guerrero Urbano

A computer aided maxillofacial sequence is presented, applied to orthognatic surgery. It consists of 5 main stages: data acquisition and integration, surgical planning, surgical simulation, and per operative assistance. The planning and…

Medical Physics · Physics 2007-05-23 Matthieu Chabanas , Christophe Marecaux , Yohan Payan , Franck Boutault

Current approaches in 3D human pose estimation primarily focus on regressing 3D joint locations, often neglecting critical physical constraints such as bone length consistency and body symmetry. This work introduces a recurrent neural…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Chih-Hsiang Hsu , Jyh-Shing Roger Jang

Deep brain stimulation (DBS) has the potential to improve the quality of life of people with a variety of neurological diseases. A key challenge in DBS is in the placement of a stimulation electrode in the anatomical location that maximizes…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Camilo Bermudez , William Rodriguez , Yuankai Huo , Allison E. Hainline , Rui Li , Robert Shults , Pierre D. DHaese , Peter E. Konrad , Benoit M. Dawant , Bennett A. Landman

Data augmentation is an effective and universal technique for improving generalization performance of deep neural networks. It could enrich diversity of training samples that is essential in medical image segmentation tasks because 1) the…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Ju Xu , Mengzhang Li , Zhanxing Zhu

In unilateral pelvic fracture reductions, surgeons attempt to reconstruct the bone fragments such that bilateral symmetry in the bony anatomy is restored. We propose to exploit this "structurally symmetric" nature of the pelvic bone, and…

Computer Vision and Pattern Recognition · Computer Science 2018-04-11 Javad Fotouhi , Mathias Unberath , Giacomo Taylor , Arash Ghaani Farashahi , Bastian Bier , Russell H. Taylor , Greg M. Osgood , M. D. , Mehran Armand , Nassir Navab

BACKGROUND: Proptosis is characterized by a protrusion of the eyeball due to an increase of the orbital tissue volume. To recover a normal eyeball positioning, the most frequent surgical technique consists in the osteotomy of orbital walls…

Medical Physics · Physics 2007-05-23 Vincent Luboz , Dominique Ambard , Pascal Swider , Franck Boutault , Yohan Payan

Radiotherapy treatment planning is a challenging large-scale optimization problem plagued by uncertainty. Following the robust optimization methodology, we propose a novel, spatially based uncertainty set for robust modeling of radiotherapy…

Optimization and Control · Mathematics 2024-05-28 Noam Goldberg , Mark P. Langer , Shimrit Shtern

When tuning software configuration for better performance (e.g., latency or throughput), an important issue that many optimizers face is the presence of local optimum traps, compounded by a highly rugged configuration landscape and…

Software Engineering · Computer Science 2024-04-09 Tao Chen , Miqing Li

Machine learning and deep learning methods have become essential for computer-assisted prediction in medicine, with a growing number of applications also in the field of mammography. Typically these algorithms are trained for a specific…

Image and Video Processing · Electrical Eng. & Systems 2021-12-03 Maria Wimmer , Gert Sluiter , David Major , Dimitrios Lenis , Astrid Berg , Theresa Neubauer , Katja Bühler

This paper introduces a new algorithm for trajectory optimization, Decoupled Reduced-space and Adaptive Feasibility-repair Trajectory Optimization (DRAFTO). It first constructs a constrained objective that accounts for smoothness, safety,…

Robotics · Computer Science 2026-03-13 Yichang Feng , Xiao Liang , Minghui Zheng

Medical image analysis relies on accurate segmentation, and benefits from controllable synthesis (of new training images). Yet both tasks of the cyclical pipeline face spatial imbalance: lesions occupy small regions against vast…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Anugunj Naman , Ayushman Singh , Gaibo Zhang , Yaguang Zhang

Recent advancements in sensor technology and deep learning have led to significant progress in 3D human body reconstruction. However, most existing approaches rely on data from a specific sensor, which can be unreliable due to the inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Anjun Chen , Xiangyu Wang , Zhi Xu , Kun Shi , Yan Qin , Yuchi Huo , Jiming Chen , Qi Ye

Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Hosseini Chagahi , Saeed Mohammadi Dashtaki , Niloufar Delfan , Nadia Mohammadi , Farshid Rostami Pouria , Behzad Moshiri , Md. Jalil Piran , Oliver Faust

Disease-modifying management aims to prevent deterioration and progression of the disease, not just relieve symptoms. Unfortunately, the development of necessary therapies is often hampered by the failure to recognize the presymptomatic…