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Adaptive Optics is a prime example of how progress in observational astronomy can be driven by technological developments. At many observatories it is now considered to be part of a standard instrumentation suite, enabling ground-based…

Instrumentation and Methods for Astrophysics · Physics 2015-06-03 R. Davies , M. Kasper

Deep learning has recently gained high interest in ophthalmology, due to its ability to detect clinically significant features for diagnosis and prognosis. Despite these significant advances, little is known about the ability of various…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Petteri Teikari , Raymond P. Najjar , Leopold Schmetterer , Dan Milea

As a revolutionary observation tool in life science, biomedical, and material science, optical microscopy allows imaging of samples with high spatial resolution and a wide field of view. However, conventional microscopy methods are limited…

Optics · Physics 2023-03-10 Yichang Shou , Jiawei Liu , Hailu Luo

We analyze how complicated a linear optical component has to be if it is to perform one of a range of functions. Specifically, we devise an approach to evaluating the number of real parameters that must be specified in the device design or…

Optics · Physics 2015-06-11 David A. B. Miller

Over the past decade, reflection matrix microscopy (RMM) and advanced image reconstruction algorithms have emerged to address the fundamental imaging depth limitations of optical microscopy in thick biological tissues and complex media. In…

Optics · Physics 2024-07-03 Sungsam Kang , Seokchan Yoon , Wonshik Choi

Until recently, conventional biochemical staining had the undisputed status as well-established benchmark for most biomedical problems related to clinical diagnostics, fundamental research and biotechnology. Despite this role as…

Novel technologies and new materials are in high demand for future energy-efficient electronic devices to overcome the fundamental limitations of miniaturization of current silicon-based devices. Two-dimensional (2D) materials show…

Computational Physics · Physics 2021-12-20 Lei Shen , Jun Zhou , Tong Yang , Ming Yang , Yuan Ping Feng

In computational imaging, hardware for signal sampling and software for object reconstruction are designed in tandem for improved capability. Examples of such systems include computed tomography (CT), magnetic resonance imaging (MRI), and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Andrew Olsen , Yolanda Hu , Vidya Ganapati

Through digital imaging, microscopy has evolved from primarily being a means for visual observation of life at the micro- and nano-scale, to a quantitative tool with ever-increasing resolution and throughput. Artificial intelligence, deep…

In recent years, mode-division multiplexing (MDM) has been proposed as a promising solution in order to increase the information capacity of optical networks both in free-space and in optical fiber transmission. Here we present the design,…

Modern imaging technologies are widely based on classical principles of light or electromagnetic wave propagation. They can be remarkably sophisticated, with recent successes ranging from single molecule microscopy to imaging far-distant…

Over the past two decades, photonic inverse design has emerged as a powerful approach to implement photonic devices with improved performance, or realize new functionalities. While the efforts over the first decade focused on proof of…

Optics · Physics 2026-02-24 Louise Schul , Sydney Mason , Sungjun Eun , Geun Ho Ahn , Jelena Vučković

The reproduction of automobile components through additive manufacturing presents significant geometric challenges, as many automotive parts feature complex, organically shaped surfaces that are difficult to fabricate accurately using…

Systems and Control · Electrical Eng. & Systems 2026-05-21 Uzair Aziz Muhammad , Zheng Liu

Centuries of effort to improve imaging has focused on perfecting and combining lenses to obtain better optical performance and new functionalities. The arrival of nanotechnology has brought to this effort engineered surfaces called…

Computational imaging modalities support a simplification of the active architectures required in an imaging system and these approaches have been validated across the electromagnetic spectrum. Recent implementations have utilized…

Classical Physics · Physics 2016-08-24 Thomas Fromenteze , Xiaojun Liu , Michael Boyarsky , Jonah Gollub , David R. Smith

Due to the wide diffusion of 3D printing technologies, geometric algorithms for Additive Manufacturing are being invented at an impressive speed. Each single step, in particular along the Process Planning pipeline, can now count on dozens…

Graphics · Computer Science 2017-09-22 Marco Livesu , Stefano Ellero , Jonás Martìnez , Sylvain Lefebvre , Marco Attene

Optical imaging and sensing systems based on diffractive elements have seen massive advances over the last several decades. Earlier generations of diffractive optical processors were, in general, designed to deliver information to an…

Optics · Physics 2024-08-14 Md Sadman Sakib Rahman , Aydogan Ozcan

We present a 3D-printing-based design to produce wire-guided liquid microfilms that can be used for versatile spectroscopic applications. We demonstrate the ability of our instrument to provide optically useful liquid microfilms with highly…

Chemical Physics · Physics 2025-07-04 Matthew J. Silverstein , Yasashri Ranathunga , Yuki Kobayashi

The scanning transmission electron microscope, a workhorse instrument in materials characterization, is being transformed into an atomic-scale material manipulation platform. With an eye on the trajectory of recent developments and the…

Applied Physics · Physics 2023-08-15 Ondrej Dyck , Andrew R. Lupini , Stephen Jesse

Photonic integrated circuits (PIC) currently rely on application-specific designs that are geared towards a particular functionality. Development of such application-specific PIC requires considerable effort and often involves several…

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