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While deep learning has exhibited remarkable predictive capabilities in various medical image tasks, its inherent black-box nature has hindered its widespread implementation in real-world healthcare settings. Our objective is to unveil the…
Pseudoprogression (PsP) is an imitation of true tumor progression (TTP) in patients with glioblastoma multiform (GBM). Differentiating them is a challenging and time-consuming task for radiologists. Although deep neural networks can…
Given the complexity of genetic risk prediction, there is a critical need for the development of novel methodologies that can effectively capture intricate genotype--phenotype relationships (e.g., nonlinear) while remaining statistically…
The significant portion of diabetic patients was affected due to major blindness caused by Diabetic retinopathy (DR). For diabetic retinopathy, lesion segmentation, and detection the comprehensive examination is delved into the deep…
The Gaussian process (GP) is a popular statistical technique for stochastic function approximation and uncertainty quantification from data. GPs have been adopted into the realm of machine learning in the last two decades because of their…
In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…
The Gaussian Process with a deep kernel is an extension of the classic GP regression model and this extended model usually constructs a new kernel function by deploying deep learning techniques like long short-term memory networks. A…
This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…
This research paper addresses the critical challenge of diabetic retinopathy (DR), a severe complication of diabetes leading to potential blindness. The proposed methodology leverages transfer learning with convolutional neural networks…
Automatic segmentation of multiple organs and tumors from 3D medical images such as magnetic resonance imaging (MRI) and computed tomography (CT) scans using deep learning methods can aid in diagnosing and treating cancer. However, organs…
Many diseases display heterogeneity in clinical features and their progression, indicative of the existence of disease subtypes. Extracting patterns of disease variable progression for subtypes has tremendous application in medicine, for…
As one kind of skin cancer, melanoma is very dangerous. Dermoscopy based early detection and recarbonization strategy is critical for melanoma therapy. However, well-trained dermatologists dominant the diagnostic accuracy. In order to solve…
Characterizing patient somatic mutations through next-generation sequencing technologies opens up possibilities for refining cancer subtypes. However, catalogues of mutations reveal that only a small fraction of the genes are altered…
Kernel method is a very powerful tool in machine learning. The trick of kernel has been effectively and extensively applied in many areas of machine learning, such as support vector machine (SVM) and kernel principal component analysis…
In this paper, we have proposed a new glaucoma classification approach that employs a wavelet neural network (WNN) on optimally enhanced retinal images features. To avoid tedious and error prone manual analysis of retinal images by…
Kernel-based subspace clustering, which addresses the nonlinear structures in data, is an evolving area of research. Despite noteworthy progressions, prevailing methodologies predominantly grapple with limitations relating to (i) the…
The 7-point checklist (7PCL) is a widely used diagnostic tool in dermoscopy for identifying malignant melanoma by assigning point values to seven specific attributes. However, the traditional 7PCL is limited to distinguishing between…
Diagnostic pathology, which is the basis and gold standard of cancer diagnosis, provides essential information on the prognosis of the disease and vital evidence for clinical treatment. Tumor region detection, subtype and grade…
Glaucoma causes an irreversible damage to retinal nerve fibers which results in vision loss, if undetected in early stage. Therefore, diagnosis of glaucoma in its early stage may prevent further vision loss. In this paper, we propose a…
Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…