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Carbon isotope labeling method is a standard metabolic engineering tool for flux quantification in living cells. To cope with the high dimensionality of isotope labeling systems, diverse algorithms have been developed to reduce the number…

Molecular Networks · Quantitative Biology 2022-02-11 Quentin Thommen , Julien Hurbain , Benjamin Pfeuty

Scientific discoveries are increasingly constrained by limited storage space and I/O capacities. For time-series simulations and experiments, their data often need to be decimated over timesteps to accommodate storage and I/O limitations.…

Estimation of small failure probabilities is one of the most important and challenging computational problems in reliability engineering. The failure probability is usually given by an integral over a high-dimensional uncertain parameter…

Computation · Statistics 2011-10-18 Konstantin M. Zuev , James L. Beck , Siu-Kui Au , Lambros S. Katafygiotis

Sparse matrices have recently played a significant and impactful role in scientific computing, including artificial intelligence-related fields. According to historical studies on sparse matrix--vector multiplication (SpMV), Krylov subspace…

Numerical Analysis · Mathematics 2024-12-24 Tomonori Kouya

As the demand for efficient, low-power computing in embedded and edge devices grows, traditional computing methods are becoming less effective for handling complex tasks. Stochastic computing (SC) offers a promising alternative by…

Robust topology optimization (RTO) improves the robustness of designs with respect to random sources in real-world structures, yet an accurate sensitivity analysis requires the solution of many systems of equations at each optimization…

Computational Engineering, Finance, and Science · Computer Science 2020-09-01 Weichen Li , Xiaojia Shelly Zhang

The acceleration of deep-learning kernels in hardware relies on matrix multiplications that are executed efficiently on Systolic Arrays (SA). To effectively trade off deep-learning training/inference quality with hardware cost, SA…

Hardware Architecture · Computer Science 2023-09-11 D. Filippas , C. Peltekis , G. Dimitrakopoulos , C. Nicopoulos

Recent hardware acceleration advances have enabled powerful specialized accelerators for finite element computations, spiking neural network inference, and sparse tensor operations. However, existing approaches face fundamental limitations:…

Hardware Architecture · Computer Science 2026-01-09 Chuanzhen Wang , Leo Zhang , Eric Liu

When implementing the gradient descent method in low precision, the employment of stochastic rounding schemes helps to prevent stagnation of convergence caused by the vanishing gradient effect. Unbiased stochastic rounding yields zero bias…

Machine Learning · Computer Science 2023-02-28 Lu Xia , Stefano Massei , Michiel E. Hochstenbach , Barry Koren

The consistent and computationally efficient stochastic statistical approach (SSA) is suggested to study kinetics of nucleation and evolution of nano-sized precipitates in alloys. An important parameter of the theory is the size of locally…

Statistical Mechanics · Physics 2010-01-11 K. Yu. Khromov , F. Soisson , A. Yu. Stroev , V. G. Vaks

The recent advancement of foundation models (FMs) has brought about a paradigm shift, revolutionizing various sectors worldwide. The popular optimizers used to train these models are stochastic gradient descent-based algorithms, which face…

Machine Learning · Computer Science 2026-01-06 Shenglong Zhou , Ouya Wang , Ziyan Luo , Yongxu Zhu , Geoffrey Ye Li

Motivation: The Stochastic Simulation Algorithm (SSA) has largely diffused in the field of systems biology. This approach needs many realizations for establishing statistical results on the system under study. It is very computationnally…

Computational Engineering, Finance, and Science · Computer Science 2014-04-02 Neri Mickael , Denis Mestivier

Long-context modeling is crucial for next-generation language models, yet the high computational cost of standard attention mechanisms poses significant computational challenges. Sparse attention offers a promising direction for improving…

Parametric stochastic simulators are ubiquitous in science, often featuring high-dimensional input parameters and/or an intractable likelihood. Performing Bayesian parameter inference in this context can be challenging. We present a neural…

Machine Learning · Statistics 2021-10-27 Benjamin Kurt Miller , Alex Cole , Patrick Forré , Gilles Louppe , Christoph Weniger

Stochastic computing (SC) offers hardware simplicity but suffers from low throughput, while high-throughput Digital Computing-in-Memory (DCIM) is bottlenecked by costly adder logic for matrix-vector multiplication (MVM). To address this…

Hardware Architecture · Computer Science 2026-01-13 Kunming Shao , Liang Zhao , Jiangnan Yu , Zhipeng Liao , Xiaomeng Wang , Yi Zou , Tim Kwang-Ting Cheng , Chi-Ying Tsui

With the increasing complexity of machine learning models, managing computational resources like memory and processing power has become a critical concern. Mixed precision techniques, which leverage different numerical precisions during…

Machine Learning · Computer Science 2026-04-20 Juyoung Yun , Sol Choi , Francois Rameau , Byungkon Kang , Zhoulai Fu

We developed a corporative stochastic approximation (CSA) type algorithm for semi-infinite programming (SIP), where the cut generation problem is solved inexactly. First, we provide general error bounds for inexact CSA. Then, we propose two…

Optimization and Control · Mathematics 2018-12-24 Bo Wei , William B. Haskell , Sixiang Zhao

Efficient analysis and simulation of multiscale stochastic systems of chemical kinetics is an ongoing area for research, and is the source of many theoretical and computational challenges. In this paper, we present a significant improvement…

Numerical Analysis · Mathematics 2016-09-21 Simon Cotter

Stochastic Rounding is a probabilistic rounding mode that is surprisingly effective in large-scale computations and low-precision arithmetic. Its random nature promotes error cancellation rather than error accumulation, resulting in slower…

Numerical Analysis · Mathematics 2024-10-15 Petros Drineas , Ilse C. F. Ipsen

We analyze the forward error in the floating point summation of real numbers, for computations in low precision or extreme-scale problem dimensions that push the limits of the precision. We present a systematic recurrence for a martingale…

Numerical Analysis · Mathematics 2022-03-31 Eric Hallman , Ilse C. F. Ipsen