Related papers: CRC-Screen: Certified DNA-Synthesis Hazard Screeni…
Foundation models for protein design raise concrete biosecurity risks, yet the community lacks a simple, reproducible baseline for sequence-level hazard screening that is explicitly evaluated under homology control and runs on commodity…
Conformal risk control (CRC) provides distribution-free guarantees for controlling the expected loss at a user-specified level. Existing theory typically assumes that the loss decreases monotonically with a tuning parameter that governs the…
Synthesis planning seeks an efficient sequence of chemical reactions that produce a target molecule. Typically, a pretrained single-step (autoregressive) retrosynthesis model is repeatedly invoked to generate such a sequence. Classifier…
This technical report presents research results achieved in the field of verification of trained Convolutional Neural Network (CNN) used for image classification in safety-critical applications. As running example, we use the obstacle…
Patch robustness certification is an emerging kind of provable defense technique against adversarial patch attacks for deep learning systems. Certified detection ensures the detection of all patched harmful versions of certified samples,…
We study the theoretical problem of synthesizing multiple DNA strands under spatial constraints, motivated by large-scale DNA synthesis technologies. In this setting, strands are arranged in an array and synthesized according to a fixed…
Motivated by DNA based data storage system, we investigate the errors that occur when synthesizing DNA strands in parallel, where each strand is appended one nucleotide at a time by the machine according to a template supersequence. If…
Language model reasoning traces are rarely all-or-nothing; they frequently contain valid intermediate steps before a critical error occurs. Existing uncertainty quantification methods typically certify final answers or entire responses,…
A fundamental property of DNA is that the reverse complement (RC) of a sequence often carries identical biological meaning. However, state-of-the-art DNA language models frequently fail to capture this symmetry, producing inconsistent…
We analyze security aspects of the SecureDNA system regarding its system design, engineering, and implementation. This system enables DNA synthesizers to screen order requests against a database of hazards. By applying novel cryptography,…
Genetic analysis methods are foundational to advancing personalized and preventative medicine, accelerating disease diagnostics, and monitoring the health of organisms and ecosystems. Current nucleic acid technologies such as polymerase…
DNA synthesis is considered as one of the most expensive components in current DNA storage systems. In this paper, focusing on a common synthesis machine, which generates multiple DNA strands in parallel following a fixed supersequence,we…
A genuine signer's signature is naturally unstable even at short time-intervals whereas, expert forgers always try to perfectly mimic a genuine signer's signature. This presents a challenge which puts a genuine signer at risk of being…
Detecting occupied subbands is a key task for wireless applications such as unlicensed spectrum access. Recently, detection methods were proposed that extract per-subband features from sub-Nyquist baseband samples and then apply…
Conformal risk control (CRC) is a recently proposed technique that applies post-hoc to a conventional point predictor to provide calibration guarantees. Generalizing conformal prediction (CP), with CRC, calibration is ensured for a set…
Graph Anomaly Detection (GAD) is critical in security-sensitive domains, yet faces reliability challenges: miscalibrated confidence estimation (underconfidence in normal nodes, overconfidence in anomalies), adversarial vulnerability of…
Fault detection is crucial for ensuring the safety and reliability of modern industrial systems. However, a significant scientific challenge is the lack of rigorous risk control and reliable uncertainty quantification in existing diagnostic…
This paper proposes a constant false alarm rate (CFAR) target detection algorithm based on the CLEAN concept and truncated statistics to mitigate the non-homogeneity of reference samples caused by sidelobe contamination and other abnormal…
AI accelerator operators are compiled into multi-stage pipeline programs where DMA, vector, matrix, and scalar units execute concurrently on shared on-chip buffers. A missing or misplaced synchronization primitive introduces…
In DNA-based data storage, DNA codes with biochemical constraints and error correction are designed to protect data reliability. Single-stranded DNA sequences with secondary structure avoidance (SSA) help to avoid undesirable secondary…