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Persona conditioning can be viewed as a behavioral prior for large language models (LLMs) and is often assumed to confer expertise and improve safety in a monotonic manner. However, its effects on high-stakes clinical decision-making remain…

Large language models (LLMs) are increasingly being adopted as the cognitive core of embodied agents. However, inherited hallucinations, which stem from failures to ground user instructions in the observed physical environment, can lead to…

Large language model (LLM) based agents have recently attracted much attention from the research and industry communities. Compared with original LLMs, LLM-based agents are featured in their self-evolving capability, which is the basis for…

Artificial Intelligence · Computer Science 2024-04-23 Zeyu Zhang , Xiaohe Bo , Chen Ma , Rui Li , Xu Chen , Quanyu Dai , Jieming Zhu , Zhenhua Dong , Ji-Rong Wen

Large language model (LLM) agents increasingly operate in settings where a single context window is far too small to capture what has happened, what was learned, and what should not be repeated. Memory -- the ability to persist, organize,…

Artificial Intelligence · Computer Science 2026-03-10 Pengfei Du

The emergence of Large Language Models (LLMs), has opened exciting possibilities for constructing computational simulations designed to replicate human behavior accurately. Current research suggests that LLM-based agents become increasingly…

Computation and Language · Computer Science 2024-12-18 Amir Taubenfeld , Yaniv Dover , Roi Reichart , Ariel Goldstein

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

Medical care follows complex clinical pathways that extend beyond isolated physician-patient encounters, emphasizing decision-making and transitions between different stages. Current benchmarks focusing on static exams or isolated dialogues…

Artificial Intelligence · Computer Science 2025-12-15 Yakun Zhu , Zhongzhen Huang , Qianhan Feng , Linjie Mu , Yannian Gu , Shaoting Zhang , Qi Dou , Xiaofan Zhang

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

Large Language Models (LLMs) are increasingly deployed as agents that orchestrate tasks and integrate external tools to execute complex workflows. We demonstrate that these interactive behaviors leave distinctive fingerprints in encrypted…

Cryptography and Security · Computer Science 2025-10-09 Yixiang Zhang , Xinhao Deng , Zhongyi Gu , Yihao Chen , Ke Xu , Qi Li , Jianping Wu

Large language models (LLMs) offer a generalizable approach for modeling patient trajectories, but suffer from the long and noisy nature of electronic health records (EHR) data in temporal reasoning. To address these challenges, we…

Artificial Intelligence · Computer Science 2026-05-18 Sihang Zeng , Yujuan Fu , Sitong Zhou , Zixuan Yu , Lucas Jing Liu , Jun Wen , Matthew Thompson , Ruth Etzioni , Meliha Yetisgen

Building scalable and reusable multi-agent decision policies from offline datasets remains a challenge in offline multi-agent reinforcement learning (MARL), as existing methods often rely on fixed observation formats and action spaces that…

Multiagent Systems · Computer Science 2026-04-28 Zhuohui Zhang , Bin Cheng , Bin He

Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore…

Computation and Language · Computer Science 2024-05-13 Taeyoon Kwon , Kai Tzu-iunn Ong , Dongjin Kang , Seungjun Moon , Jeong Ryong Lee , Dosik Hwang , Yongsik Sim , Beomseok Sohn , Dongha Lee , Jinyoung Yeo

Driving in safety-critical scenarios requires quick, context-aware decision-making grounded in both situational understanding and experiential reasoning. Large Language Models (LLMs), with their powerful general-purpose reasoning…

Artificial Intelligence · Computer Science 2025-06-26 Wenbin Gan , Minh-Son Dao , Koji Zettsu

Large language model (LLM)-powered agents are increasingly used in recommender systems (RSs) to achieve personalized behavior modeling, where the memory mechanism plays a pivotal role in enabling the agents to autonomously explore, learn…

Cryptography and Security · Computer Science 2025-10-22 Shiyi Yang , Zhibo Hu , Xinshu Li , Chen Wang , Tong Yu , Xiwei Xu , Liming Zhu , Lina Yao

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

Large Language Models (LLMs) as clinical agents require careful behavioral adaptation. While adept at reactive tasks (e.g., diagnosis reasoning), LLMs often struggle with proactive engagement, like unprompted identification of critical…

As demand for mental health care outpaces clinician-delivered assessment, scalable screening tools are increasingly needed. Large language models (LLMs) may identify psychiatric risk from patient narratives, but their reliability across…

Computation and Language · Computer Science 2026-05-26 Jianfeng Zhu , Megan Korhummel , Ruoming Jin , Karin G. Coifman

Large Language Models (LLMs) have attained human-level accuracy on medical question-answer (QA) benchmarks. However, their limitations in navigating open-ended clinical scenarios have recently been shown, raising concerns about the…

Computation and Language · Computer Science 2025-11-13 Jonathan Kim , Anna Podlasek , Kie Shidara , Feng Liu , Ahmed Alaa , Danilo Bernardo

Driven by the rapid advancements of Large Language Models (LLMs), LLM-based agents have emerged as powerful intelligent systems capable of human-like cognition, reasoning, and interaction. These agents are increasingly being deployed across…