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We explore different strategies to integrate prior domain knowledge into the design of a deep neural network (DNN). We focus on graph neural networks (GNN), with a use case of estimating the potential energy of chemical systems (molecules…

Machine Learning · Computer Science 2022-08-26 Jay Morgan , Adeline Paiement , Christian Klinke

Accurately identifying gas mixtures and estimating their concentrations are crucial across various industrial applications using gas sensor arrays. However, existing models face challenges in generalizing across heterogeneous datasets,…

Machine Learning · Computer Science 2024-12-19 Ding Wang , Lei Wang , Huilin Yin , Guoqing Gu , Zhiping Lin , Wenwen Zhang

Graph neural networks (GNNs) are widely used as surrogates for costly experiments and first-principles simulations to study the behavior of compounds at atomistic scale, and their architectural complexity is constantly increasing to enable…

Machine Learning · Computer Science 2026-05-04 Arindam Chowdhury , Massimiliano Lupo Pasini

The prediction of physicochemical properties from molecular structures is a crucial task for artificial intelligence aided molecular design. A growing number of Graph Neural Networks (GNNs) have been proposed to address this challenge.…

Machine Learning · Computer Science 2020-11-17 Shuo Zhang , Yang Liu , Lei Xie

We propose excess Gibbs free energy graph neural networks (GE-GNNs) for predicting composition-dependent activity coefficients of binary mixtures. The GE-GNN architecture ensures thermodynamic consistency by predicting the molar excess…

Disordered Systems and Neural Networks · Physics 2024-11-05 Jan G. Rittig , Alexander Mitsos

Graph neural networks (GNNs) have achieved superior performance in various applications, but training dedicated GNNs can be costly for large-scale graphs. Some recent work started to study the pre-training of GNNs. However, none of them…

Machine Learning · Computer Science 2021-10-27 Qi Zhu , Carl Yang , Yidan Xu , Haonan Wang , Chao Zhang , Jiawei Han

The accurate prediction of tandem mass spectra from molecular structures has the potential to unlock new metabolomic discoveries by augmenting the community's libraries of experimental reference standards. Cheminformatic spectrum prediction…

Quantitative Methods · Quantitative Biology 2024-01-10 Samuel Goldman , Janet Li , Connor W. Coley

Inexpensive machine learning potentials are increasingly being used to speed up structural optimization and molecular dynamics simulations of materials by iteratively predicting and applying interatomic forces. In these settings, it is…

Chemical Physics · Physics 2023-09-12 Jonas Busk , Mikkel N. Schmidt , Ole Winther , Tejs Vegge , Peter Bjørn Jørgensen

Graph Neural Networks (GNNs) learn from graph-structured data by passing local messages between neighboring nodes along edges on certain topological layouts. Typically, these topological layouts in modern GNNs are deterministically computed…

Machine Learning · Computer Science 2024-02-27 Xinjian Zhao , Chaolong Ying , Tianshu Yu

This paper shows how Graph Neural Networks can be used for learning distributed coordination mechanisms in connected teams of robots. We capture the relational aspect of robot coordination by modeling the robot team as a graph, where each…

Robotics · Computer Science 2019-01-29 Amanda Prorok

Accurate prediction of physical properties is critical for discovering and designing novel materials. Machine learning technologies have attracted significant attention in the materials science community for their potential for large-scale…

Materials Science · Physics 2021-11-24 Boyu Zhang , Mushen Zhou , Jianzhong Wu , Fuchang Gao

Constructing appropriate representations of molecules lies at the core of numerous tasks such as material science, chemistry and drug designs. Recent researches abstract molecules as attributed graphs and employ graph neural networks (GNN)…

Machine Learning · Computer Science 2021-07-29 Jianwen Chen , Shuangjia Zheng , Ying Song , Jiahua Rao , Yuedong Yang

For joint inference over multiple variables, a variety of structured prediction techniques have been developed to model correlations among variables and thereby improve predictions. However, many classical approaches suffer from one of two…

Machine Learning · Computer Science 2020-01-07 Colin Graber , Alexander Schwing

Deep learning applications at the network edge lead to a significant growth in AI-related carbon emissions, presenting a critical sustainability challenge. The existing edge computing frameworks optimize for latency and throughput, but they…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-02 Guilin Zhang , Wulan Guo , Ziqi Tan , Chuanyi Sun , Hailong Jiang

Molecular property prediction is of crucial importance in many disciplines such as drug discovery, molecular biology, or material and process design. The frequently employed quantitative structure-property/activity relationships…

Biomolecules · Quantitative Biology 2024-01-17 Jan G. Rittig , Qinghe Gao , Manuel Dahmen , Alexander Mitsos , Artur M. Schweidtmann

Graph neural networks are currently leading the performance charts in learning-based molecule property prediction and classification. Computational chemistry has, therefore, become the a prominent testbed for generic graph neural networks,…

Machine Learning · Computer Science 2020-02-04 Eliya Nachmani , Lior Wolf

Deep convolutional neural network (CNN) training via iterative optimization has had incredible success in finding optimal parameters. However, modern CNN architectures often contain millions of parameters. Thus, any given model for a single…

Machine Learning · Computer Science 2023-08-21 Stone Yun , Alexander Wong

Graph Neural Networks (GNN) have recently gained popularity in the forecasting domain due to their ability to model complex spatial and temporal patterns in tasks such as traffic forecasting and region-based demand forecasting. Most of…

Machine Learning · Computer Science 2023-12-08 Abishek Sriramulu , Nicolas Fourrier , Christoph Bergmeir

Graphical models are widely used in diverse application domains to model the conditional dependencies amongst a collection of random variables. In this paper, we consider settings where the graph structure is covariate-dependent, and…

Machine Learning · Statistics 2025-04-24 Jiahe Lin , Yikai Zhang , George Michailidis

Graph neural networks are deep neural networks designed for graphs with attributes attached to nodes or edges. The number of research papers in the literature concerning these models is growing rapidly due to their impressive performance on…

Machine Learning · Computer Science 2024-12-30 James H. Tanis , Chris Giannella , Adrian V. Mariano