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Masked diffusion models (MDMs) have shown promise in language modeling, yet their scalability and effectiveness in core language tasks, such as text generation and language understanding, remain underexplored. This paper establishes the…

Artificial Intelligence · Computer Science 2025-03-03 Shen Nie , Fengqi Zhu , Chao Du , Tianyu Pang , Qian Liu , Guangtao Zeng , Min Lin , Chongxuan Li

Large denoising diffusion models, such as Stable Diffusion, have been trained on billions of image-caption pairs to perform text-conditioned image generation. As a byproduct of this training, these models have acquired general knowledge…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Alexandros Graikos , Nebojsa Jojic , Dimitris Samaras

Inverse protein folding generates valid amino acid sequences that can fold into a desired protein structure, with recent deep-learning advances showing strong potential and competitive performance. However, challenges remain, such as…

Biomolecules · Quantitative Biology 2025-07-29 Peizhen Bai , Filip Miljković , Xianyuan Liu , Leonardo De Maria , Rebecca Croasdale-Wood , Owen Rackham , Haiping Lu

Discrete diffusion language models (dLLMs) accelerate text generation by unmasking multiple tokens in parallel. However, parallel decoding introduces a distributional mismatch: it approximates the joint conditional using a fully factorized…

Computation and Language · Computer Science 2026-04-06 Liran Ringel , Ameen Ali , Yaniv Romano

Diffusion models (DMs) have demonstrated remarkable ability to generate diverse and high-quality images by efficiently modeling complex data distributions. They have also been explored as powerful generative priors for signal recovery,…

Machine Learning · Computer Science 2025-05-28 Anqi Tang , Youming Chen , Shuchen Xue , Zhaoqiang Liu

A major bottleneck of standard auto-regressive large language models is that their inference process is inherently sequential, resulting in very long and costly inference times. To circumvent this, practitioners proposed a class of language…

Machine Learning · Computer Science 2025-11-11 Sitan Chen , Kevin Cong , Jerry Li

Diffusion models excel at capturing the natural design spaces of images, molecules, DNA, RNA, and protein sequences. However, rather than merely generating designs that are natural, we often aim to optimize downstream reward functions while…

Diffusion models (DMs) have rapidly emerged as a powerful framework for image generation and restoration. However, existing DMs are primarily trained in a supervised manner by using a large corpus of clean images. This reliance on clean…

Image and Video Processing · Electrical Eng. & Systems 2025-10-15 Brett Levac , Jon Tamir , Marcelo Pereyra , Julian Tachella

Diffusion Probabilistic Models (DPMs) have recently shown remarkable performance in image generation tasks, which are capable of generating highly realistic images. When adopting DPMs for image restoration tasks, the crucial aspect lies in…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Yi Zhang , Xiaoyu Shi , Dasong Li , Xiaogang Wang , Jian Wang , Hongsheng Li

Diffusion models (DM) can gradually learn to remove noise, which have been widely used in artificial intelligence generated content (AIGC) in recent years. The property of DM for eliminating noise leads us to wonder whether DM can be…

Information Theory · Computer Science 2023-09-19 Tong Wu , Zhiyong Chen , Dazhi He , Liang Qian , Yin Xu , Meixia Tao , Wenjun Zhang

Despite its success in image synthesis, we observe that diffusion probabilistic models (DPMs) often lack contextual reasoning ability to learn the relations among object parts in an image, leading to a slow learning process. To solve this…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Shanghua Gao , Pan Zhou , Ming-Ming Cheng , Shuicheng Yan

Diffusion models are powerful tools for sampling from high-dimensional distributions by progressively transforming pure noise into structured data through a denoising process. When equipped with a guidance mechanism, these models can also…

Machine Learning · Computer Science 2026-05-04 Saeed Mohseni-Sehdeh , Walid Saad , Kei Sakaguchi , Tao Yu

Diffusion models (DMs) are a powerful generative framework that have attracted significant attention in recent years. However, the high computational cost of training DMs limits their practical applications. In this paper, we start with a…

Machine Learning · Computer Science 2024-04-12 Tianshuo Xu , Peng Mi , Ruilin Wang , Yingcong Chen

Denoising diffusion probabilistic models (DDPMs) have achieved high quality image generation without adversarial training, yet they require simulating a Markov chain for many steps to produce a sample. To accelerate sampling, we present…

Machine Learning · Computer Science 2022-10-07 Jiaming Song , Chenlin Meng , Stefano Ermon

Recent advances in generative modeling with diffusion processes (DPs) enabled breakthroughs in image synthesis. Despite impressive image quality, these models have various prompt compliance problems, including low recall in generating…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Deepak Sridhar , Abhishek Peri , Rohith Rachala , Nuno Vasconcelos

Diffusion models (DMs) are a class of generative models that allow sampling from a distribution learned over a training set. When applied to solving inverse problems, the reverse sampling steps are modified to approximately sample from a…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Ismail Alkhouri , Shijun Liang , Cheng-Han Huang , Jimmy Dai , Qing Qu , Saiprasad Ravishankar , Rongrong Wang

Medical imaging applications are highly specialized in terms of human anatomy, pathology, and imaging domains. Therefore, annotated training datasets for training deep learning applications in medical imaging not only need to be highly…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Arjun Krishna , Ge Wang , Klaus Mueller

Conditional diffusion models have demonstrated impressive performance in image manipulation tasks. The general pipeline involves adding noise to the image and then denoising it. However, this method faces a trade-off problem: adding too…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Luozhou Wang , Shuai Yang , Shu Liu , Ying-cong Chen

Many interesting tasks in image restoration can be cast as linear inverse problems. A recent family of approaches for solving these problems uses stochastic algorithms that sample from the posterior distribution of natural images given the…

Image and Video Processing · Electrical Eng. & Systems 2022-10-14 Bahjat Kawar , Michael Elad , Stefano Ermon , Jiaming Song

We study the inductive biases of diffusion models with a conditioning-variable, which have seen widespread application as both text-conditioned generative image models and observation-conditioned continuous control policies. We observe that…

Machine Learning · Computer Science 2025-12-23 Daniel Pfrommer , Zehao Dou , Christopher Scarvelis , Max Simchowitz , Ali Jadbabaie