English
Related papers

Related papers: Protein folding on a 64 qubit trapped-ion hardware…

200 papers

We have designed, fabricated and tested an XY-addressable readout system that is specifically tailored for the reading of superconducting flux qubits in an integrated circuit that could enable adiabatic quantum optimization. In such a…

The prevalent approach to executing quantum algorithms on quantum computers is to break-down the algorithms to a concatenation of universal gates, typically single and two-qubit gates. However such a decomposition results in long gate…

Quantum Physics · Physics 2020-03-25 Yotam Shapira , Ravid Shaniv , Tom Manovitz , Nitzan Akerman , Lee Peleg , Lior Gazit , Roee Ozeri , Ady Stern

Constrained binary optimization aims to find an optimal assignment to minimize or maximize the objective meanwhile satisfying the constraints, which is a representative NP problem in various domains, including transportation, scheduling,…

Quantum Physics · Physics 2025-08-18 Debin Xiang , Qifan Jiang , Liqiang Lu , Siwei Tan , Jianwei Yin

Optimization problems become fundamentally challenging as the number of variables increases. Because the volume of the search space grows exponentially, classical algorithms frequently fail to locate the global minimum of non-convex…

Quantum Physics · Physics 2026-04-23 Dominik Soós , Marc Paterno , John Stenger , Nikos Chrisochoides

The conformational change of biological macromolecule is investigated from the point of quantum transition. A quantum theory on protein folding is proposed. Compared with other dynamical variables such as mobile electrons, chemical bonds…

Biomolecules · Quantitative Biology 2013-08-06 LiaoFu Luo

Topological quantum error correction is a milestone in the scaling roadmap of quantum computers, which targets circuits with trillions of gates that would allow running quantum algorithms for real-world problems. The square-lattice surface…

Quantum Physics · Physics 2025-02-12 César Benito , Esperanza López , Borja Peropadre , Alejandro Bermudez

We, the QAIMS lab lab at the Aerospace Faculty of TU Delft, participated as finalists in the Airbus/BMW Quantum Computing Challenge 2024. Stacking sequence retrieval, a complex combinatorial task within a bi-level optimization framework, is…

We investigate ancilla-free linear combination of unitaries (LCU) as a framework for approximating complex quantum circuits. This is particularly effective for quantum optimization algorithms, where candidate solutions can be evaluated…

Quantum Physics · Physics 2026-05-20 Almudena Carrera Vazquez , Daniel J. Egger , Stefan Woerner

Accurate protein structure prediction from amino-acid sequences is critical to better understanding the protein function. Recent advances in this area largely benefit from more precise inter-residue distance and orientation predictions,…

Machine Learning · Computer Science 2021-06-01 Jiaxiang Wu , Shitong Luo , Tao Shen , Haidong Lan , Sheng Wang , Junzhou Huang

We introduce a construction for protocols for fault-tolerant quantum computing based on code concatenation and transversal gates. These protocols can be interpreted as families of quantum circuits of low-weight stabilizer measurements…

Quantum Physics · Physics 2025-06-17 Daniel Litinski

Quantum-chemical fragmentation methods offer an efficient approach for the treatment of large proteins, in particular if local target quantities such as protein--ligand interaction energies, enzymatic reaction energies, or spectroscopic…

Chemical Physics · Physics 2024-07-17 Mario Wolter , Moritz von Looz , Henning Meyerhenke , Christoph R. Jacob

Bayesian optimization (BayesOpt) is a gold standard for query-efficient continuous optimization. However, its adoption for drug design has been hindered by the discrete, high-dimensional nature of the decision variables. We develop a new…

The development of tailored materials for specific applications is an active field of research in chemistry, material science and drug discovery. The number of possible molecules that can be obtained from a set of atomic species grow…

One of the most important tasks in modern quantum science is to coherently control and entangle many-body systems, and to subsequently use these systems to realize powerful quantum technologies such as quantum-enhanced sensors. However,…

Black-box optimization (BBO) is used in materials design, drug discovery, and hyperparameter tuning in machine learning. The world is experiencing several of these problems. In this review, a factorization machine with quantum annealing or…

Statistical Mechanics · Physics 2026-04-30 Ryo Tamura , Yuya Seki , Yuki Minamoto , Koki Kitai , Yoshiki Matsuda , Shu Tanaka , Koji Tsuda

Measurement-based quantum computing (MBQC) in linear optical systems is promising for near-future quantum computing architecture. However, the nondeterministic nature of entangling operations and photon losses hinder the large-scale…

Quantum Physics · Physics 2023-04-25 Seok-Hyung Lee , Srikrishna Omkar , Yong Siah Teo , Hyunseok Jeong

Models of protein energetics which neglect interactions between amino acids that are not adjacent in the native state, such as the Go model, encode or underlie many influential ideas on protein folding. Implicit in this simplification is a…

Biomolecules · Quantitative Biology 2009-10-08 Brian C. Gin , Juan P. Garrahan , Phillip L. Geissler

In digital baseband processing, the forward error correction (FEC) unit belongs to the most demanding components in terms of computational complexity and power consumption. Hence, efficient implementation of FEC decoders is crucial for next…

Information Theory · Computer Science 2024-06-04 Claus Kestel , Lucas Johannsen , Norbert Wehn

A recent paper by Jordan et al. introduced Decoded Quantum Interferometry (DQI), a novel quantum algorithm that uses the quantum Fourier transform to reduce linear optimization problems -- max-XORSAT and max-LINSAT -- to decoding problems.…

Quantum Physics · Physics 2026-03-11 Daniel Cohen Hillel

The union-find decoder is a leading algorithmic approach to the correction of quantum errors on the surface code, achieving code thresholds comparable to minimum-weight perfect matching (MWPM) with amortised computational time scaling…

Quantum Physics · Physics 2025-04-10 Sam J. Griffiths , Dan E. Browne