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Domain specific large language models are increasingly used to support patient education, triage, and clinical decision making in ophthalmology, making rigorous evaluation essential to ensure safety and accuracy. This study evaluated four…

Accurate symptom-to-disease classification and clinically grounded treatment recommendations remain challenging, particularly in heterogeneous patient settings with high diagnostic risk. Existing large language model (LLM)-based systems…

Large Language models (LLMs) have demonstrated state-of-the-art performance in various natural language processing (NLP) tasks across multiple domains, yet they are prone to shortcut learning and factual inconsistencies. This research…

Computation and Language · Computer Science 2024-04-09 Shreyasi Mandal , Ashutosh Modi

Large language models (LLMs) show promise in clinical decision support yet risk acquiescing to patient pressure for inappropriate care. We introduce SycoEval-EM, a multi-agent simulation framework evaluating LLM robustness through…

Artificial Intelligence · Computer Science 2026-03-05 Dongshen Peng , Yi Wang , Austin Schoeffler , Carl Preiksaitis , Christian Rose

As large language models (LLMs) are deployed in high-stakes domains like healthcare, understanding how well their decision-making aligns with human preferences and values becomes crucial, especially when we recognize that there is no single…

Computation and Language · Computer Science 2024-10-01 Isaac Kohane

The SLAM paper demonstrated that on-device Small Language Models (SLMs) are a viable and cost-effective alternative to API-based Large Language Models (LLMs), such as OpenAI's GPT-4, offering comparable performance and stability. However,…

Computation and Language · Computer Science 2024-07-19 Roland Daynauth , Jason Mars

Large Language Models (LLMs) have advanced various Natural Language Processing (NLP) tasks, such as text generation and translation, among others. However, these models often generate texts that can perpetuate biases. Existing approaches to…

Computation and Language · Computer Science 2025-01-07 Shaina Raza , Oluwanifemi Bamgbose , Shardul Ghuge , Fatemeh Tavakol , Deepak John Reji , Syed Raza Bashir

As Large Language Models (LLMs) are increasingly integrated into healthcare to address complex inquiries, ensuring their reliability remains a critical challenge. Recent studies have highlighted that generic LLMs often struggle in clinical…

Computation and Language · Computer Science 2026-04-01 Bian Sun , Zhenjian Wang , Orvill de la Torre , Zirui Wang

Semantic leakage is a phenomenon recently introduced by Gonen et al. (2024). It refers to a situation in which associations learnt from the training data emerge in language model generations in an unexpected and sometimes undesired way.…

Computation and Language · Computer Science 2025-01-14 Veronika Smilga

Small Language Models (SLMs) have gained substantial attention due to their ability to execute diverse language tasks successfully while using fewer computer resources. These models are particularly ideal for deployment in limited…

Computation and Language · Computer Science 2025-05-30 Tanjil Hasan Sakib , Md. Tanzib Hosain , Md. Kishor Morol

Large language models (LLMs) have made significant progress in various domains, including healthcare. However, the specialized nature of clinical language understanding tasks presents unique challenges and limitations that warrant further…

Computation and Language · Computer Science 2023-08-01 Yuqing Wang , Yun Zhao , Linda Petzold

Small language models (SLMs) are increasingly deployed on edge devices, making their safety alignment crucial yet challenging. Current shallow alignment methods that rely on direct refusal of malicious queries fail to provide robust…

Cryptography and Security · Computer Science 2025-11-11 Haonan Shi , Guoli Wang , Tu Ouyang , An Wang

The increasing use of tools and solutions based on Large Language Models (LLMs) for various tasks in the medical domain has become a prominent trend. Their use in this highly critical and sensitive domain has thus raised important questions…

Computation and Language · Computer Science 2024-01-09 Jean-Baptiste Excoffier , Tom Roehr , Alexei Figueroa , Jens-Michalis Papaioannou , Keno Bressem , Matthieu Ortala

Small language models (SLMs) offer significant deployment advantages but often struggle to match the dialogue quality of larger models in open-domain settings. In this paper, we propose a multi-dimensional prompt-chaining framework that…

Computation and Language · Computer Science 2026-01-06 Livia Leong Hui Teng

Clinical oncology generates vast, unstructured data that often contain inconsistencies, missing information, and ambiguities, making it difficult to extract reliable insights for data-driven decision-making. General-purpose large language…

Computation and Language · Computer Science 2025-03-12 Morteza Rohanian , Tarun Mehra , Nicola Miglino , Farhad Nooralahzadeh , Michael Krauthammer , Andreas Wicki

Pre-trained Large Language Models (LLMs) often struggle on out-of-domain datasets like healthcare focused text. We explore specialized pre-training to adapt smaller LLMs to different healthcare datasets. Three methods are assessed:…

Computation and Language · Computer Science 2024-04-01 Niall Taylor , Dan Schofield , Andrey Kormilitzin , Dan W Joyce , Alejo Nevado-Holgado

The growing public demand for accessible biomedical information calls for scalable text simplification. While large language models (LLMs) offer solutions, they too struggle with balancing improved readability against preservation of…

Computation and Language · Computer Science 2026-05-07 P. Bilha Githinji , Aikaterini Melliou , Zeming Liang , Lian Zhang , Peiwu Qin

A prominent achievement of natural language processing (NLP) is its ability to understand and generate meaningful human language. This capability relies on complex feedforward transformer block architectures pre-trained on large language…

Computation and Language · Computer Science 2025-11-11 Ronit D. Gross , Yarden Tzach , Tal Halevi , Ella Koresh , Ido Kanter

High computation costs and latency of large language models such as GPT-4 have limited their deployment in clinical settings. Small language models (SLMs) offer a cost-effective alternative, but their limited capacity requires biomedical…

Machine Translation (MT) plays a pivotal role in cross-lingual information access, public policy communication, and equitable knowledge dissemination. However, critical meaning errors, such as factual distortions, intent reversals, or…

Computation and Language · Computer Science 2026-02-13 Muskaan Chopra , Lorenz Sparrenberg , Rafet Sifa
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