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Almost 50% depression patients face the risk of going into relapse. The risk increases to 80% after the second episode of depression. Although, depression detection from social media has attained considerable attention, depression relapse…

Vocoders, encoding speech signals into acoustic features and allowing for speech signal reconstruction from them, have been studied for decades. Recently, the rise of deep learning has particularly driven the development of neural vocoders…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-03 Shaowen Chen , Tomoki Toda

By focusing on melancholic features with biological homogeneity, this study aimed to identify a small number of critical functional connections (FCs) that were specific only to the melancholic type of MDD. On the resting-state fMRI data,…

Accurate diagnosis of Alzheimer's Disease (AD) entails clinical evaluation of multiple cognition metrics and biomarkers. Metrics such as the Alzheimer's Disease Assessment Scale - Cognitive test (ADAS-cog) comprise multiple subscores that…

Machine Learning · Statistics 2017-08-16 Lev E. Givon , Laura J. Mariano , David O'Dowd , John M. Irvine , Abraham R. Schneider

Automatic depression detection from conversational interactions holds significant promise for scalable screening but remains hindered by severe data scarcity and a lack of clinical interpretability. Existing approaches typically rely on…

Computation and Language · Computer Science 2026-04-28 Rishitej Reddy Vyalla , Kritarth Prasad , Avinash Anand , Erik Cambria , Shaoxiong Ji , Faten S. Alamri , Zhengkui Wang

Autism spectrum disorder is one of the leading neurodevelopmental disorders in our world, present in over 1% of the population and rapidly increasing in prevalence, yet the condition lacks a robust, objective, and efficient diagnostic.…

Neurons and Cognition · Quantitative Biology 2024-03-04 Annie Adhikary

Mild Cognitive Impairment (MCI) is an early stage of Alzheimer's disease (AD), a form of neurodegenerative disorder. Early identification of MCI is crucial for delaying its progression through timely interventions. Existing research has…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-18 Kristin Qi , Jiatong Shi , Caroline Summerour , John A. Batsis , Xiaohui Liang

Deep convolutional neural networks are being actively investigated in a wide range of speech and audio processing applications including speech recognition, audio event detection and computational paralinguistics, owing to their ability to…

Machine Learning · Computer Science 2018-01-16 Che-Wei Huang , Shrikanth. S. Narayanan

Speaker diarization accuracy can be affected by both acoustics and conversation characteristics. Determining the cause of diarization errors is difficult because speaker voice acoustics and conversation structure co-vary, and the…

Audio and Speech Processing · Electrical Eng. & Systems 2021-06-11 Scott Seyfarth , Sundararajan Srinivasan , Katrin Kirchhoff

The area under the ROC curve (AUC) is the standard measure of a biomarker's discriminatory accuracy; however, naive AUC estimates can be misleading when validation cohorts differ from the intended target population. Such covariate shifts…

Methodology · Statistics 2025-11-20 Jiajun Liu , Guangcai Mao , Xiaofei Wang

Individuals often align their speaking patterns with their interlocutors, a phenomenon linked to engagement and rapport. While well documented in task-oriented dialogues, less is known about entrainment in naturalistic, non-task and virtual…

Human-Computer Interaction · Computer Science 2026-04-20 Thanushi Withanage , Elizabeth Redcay , Carol Espy-Wilson

Depression and post traumatic stress disorder (PTSD) often co-occur with connected symptoms, complicating automated assessment, which is often binary and disorder specific. Clinically useful diagnosis needs severity aware cross disorder…

Computation and Language · Computer Science 2025-10-24 Filippo Cenacchi , Deborah Richards , Longbing Cao

With the periodic rise and fall of COVID-19 and countries being inflicted by its waves, an efficient, economic, and effortless diagnosis procedure for the virus has been the utmost need of the hour. COVID-19 positive individuals may even be…

Sound · Computer Science 2026-05-21 Saranga Kingkor Mahanta , Darsh Kaushik , Shubham Jain , Hoang Van Truong , Koushik Guha

The early diagnosis of Alzheimer's Disease (AD) through non invasive methods remains a significant healthcare challenge. We present NeuroXVocal, a novel dual-component system that not only classifies but also explains potential AD cases…

In a depression-diagnosis-directed clinical session, doctors initiate a conversation with ample emotional support that guides the patients to expose their symptoms based on clinical diagnosis criteria. Such a dialogue system is…

Computation and Language · Computer Science 2022-10-25 Binwei Yao , Chao Shi , Likai Zou , Lingfeng Dai , Mengyue Wu , Lu Chen , Zhen Wang , Kai Yu

Acoustic environment characterization opens doors for sound reproduction innovations, smart EQing, speech enhancement, hearing aids, and forensics. Reverberation time, clarity, and direct-to-reverberant ratio are acoustic parameters that…

Sound · Computer Science 2020-10-22 Paul Callens , Milos Cernak

In contemporary society, the escalating pressures of life and work have propelled psychological disorders to the forefront of modern health concerns, an issue that has been further accentuated by the COVID-19 pandemic. The prevalence of…

Machine Learning · Computer Science 2024-01-09 Qiang Li , Yufeng Wu , Zhan Xu , Hefeng Zhou

In the era of advanced artificial intelligence and human-computer interaction, identifying emotions in spoken language is paramount. This research explores the integration of deep learning techniques in speech emotion recognition, offering…

Sound · Computer Science 2023-10-20 Hanan Hamza , Fiza Gafoor , Fathima Sithara , Gayathri Anil , V. S. Anoop

Background and Objective: The connection between depression and autonomous nervous system (ANS) is well documented in scientific literature. Heart rate variability (HRV) is a rich source of information for studying the dynamics of this…

Neurons and Cognition · Quantitative Biology 2021-10-19 Milena Čukić , Danka Savić , Julia Sidorova

Several brain foundation models (FM) have recently been proposed to predict brain disorders by modelling dynamic functional connectivity (FC). While they demonstrate remarkable model performance and zero- or few-shot generalization, the…

Neurons and Cognition · Quantitative Biology 2026-04-27 Deepank Girish , Yi Hao Chan , Sukrit Gupta , Jing Xia , Jagath C. Rajapakse