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In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Image registration is useful for quantifying morphological changes in longitudinal MR images from prostate cancer patients. This paper describes a development in improving the learning-based registration algorithms, for this challenging…

Computational pathology (CPath) has shown great potential in mining actionable insights from Whole Slide Images (WSIs). Deep Learning (DL) has been at the center of modern CPath, and while it delivers unprecedented performance, it is also…

Despite the recent success of domain generalization in medical image segmentation, voxel-wise annotation for all source domains remains a huge burden. Semi-supervised domain generalization has been proposed very recently to combat this…

Effective clinical deployment of deep learning models in healthcare demands high generalization performance to ensure accurate diagnosis and treatment planning. In recent years, significant research has focused on improving the…

In the past years, deep learning has seen an increase in usage in the domain of histopathological applications. However, while these approaches have shown great potential, in high-risk environments deep learning models need to be able to…

Domain generalization (DG) strives to address distribution shifts across diverse environments to enhance model's generalizability. Current DG approaches are confined to acquiring robust representations with continuous features, specifically…

The challenge of overfitting, in which the model memorizes the training data and fails to generalize to test data, has become increasingly significant in the training of large neural networks. To tackle this challenge, Sharpness-Aware…

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image…

In digital pathology, different staining procedures and scanners cause substantial color variations in whole-slide images (WSIs), especially across different laboratories. These color shifts result in a poor generalization of deep…

In this paper, we explore how conventional image enhancement can improve model robustness in medical image analysis. By applying commonly used normalization methods to images from various vendors and studying their influence on model…

Deep learning has demonstrated remarkable achievements in medical image segmentation. However, prevailing deep learning models struggle with poor generalization due to (i) intra-class variations, where the same class appears differently in…

Deep Learning has thrived on the emergence of biomedical big data. However, medical datasets acquired at different institutions have inherent bias caused by various confounding factors such as operation policies, machine protocols,…

Domain generalization typically requires data from multiple source domains for model learning. However, such strong assumption may not always hold in practice, especially in medical field where the data sharing is highly concerned and…

Histopathology whole slide images (WSIs) can reveal significant inter-hospital variability such as illumination, color or optical artifacts. These variations, caused by the use of different scanning protocols across medical centers…

Image inpainting techniques have shown promising improvement with the assistance of generative adversarial networks (GANs) recently. However, most of them often suffered from completed results with unreasonable structure or blurriness. To…

Enhancing the domain generalization performance of Face Anti-Spoofing (FAS) techniques has emerged as a research focus. Existing methods are dedicated to extracting domain-invariant features from various training domains. Despite the…

Data augmentation is widely used to enhance generalization in visual classification tasks. However, traditional methods struggle when source and target domains differ, as in domain adaptation, due to their inability to address domain gaps.…

With too few samples or too many model parameters, overfitting can inhibit the ability to generalise predictions to new data. Within medical imaging, this can occur when features are incorrectly assigned importance such as distinct hospital…

Domain generalization is the task of learning models that generalize to unseen target domains. We propose a simple yet effective method for domain generalization, named cross-domain ensemble distillation (XDED), that learns domain-invariant…