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Insufficient performance of optimization approaches for fitting of mathematical models is still a major bottleneck in systems biology. In this manuscript, the reasons and methodological challenges are summarized as well as their impact in…

Performance · Computer Science 2019-07-09 Clemens Kreutz

Hundreds of Evolutionary Computation approaches have been reported. From an evolutionary perspective they focus on two fundamental mechanisms: cultural inheritance in Swarm Intelligence and genetic inheritance in Evolutionary Algorithms.…

Neural and Evolutionary Computing · Computer Science 2022-11-28 Sizhe Yuen , Thomas H. G. Ezard , Adam J. Sobey

Parameter control and dynamic algorithm configuration study how to dynamically choose suitable configurations of a parametrized algorithm during the optimization process. Despite being an intensively researched topic in evolutionary…

Neural and Evolutionary Computing · Computer Science 2025-07-14 Gianluca Covini , Denis Antipov , Carola Doerr

Benchmark Design in Black-Box Optimization (BBO) is a fundamental yet open-ended topic. Early BBO benchmarks are predominantly human-crafted, introducing expert bias and constraining diversity. Automating this design process can relieve the…

Neural and Evolutionary Computing · Computer Science 2026-02-03 Chen Wang , Sijie Ma , Zeyuan Ma , Yue-Jiao Gong

Evolutionary Multi-Objective Optimization Algorithms (EMOAs) are widely employed to tackle problems with multiple conflicting objectives. Recent research indicates that not all objectives are equally important to the decision-maker (DM). In…

Artificial Intelligence · Computer Science 2024-11-08 Seyed Mahdi Shavarani , Mahmoud Golabi , Richard Allmendinger , Lhassane Idoumghar

Choices in scientific research and management require balancing multiple, often competing objectives.Multiple-objective optimization (MOO) provides a unifying framework for solving multiple objective problems. Model selection is a critical…

Applications · Statistics 2018-10-26 Perry Williams , William Kendall , Mevin Hooten

Evolutionary algorithms excel in solving complex optimization problems, especially those with multiple objectives. However, their stochastic nature can sometimes hinder rapid convergence to the global optima, particularly in scenarios…

Neural and Evolutionary Computing · Computer Science 2024-05-10 Zeyi Wang , Songbai Liu , Jianyong Chen , Kay Chen Tan

Motivation: Estimating parameters from data is a key stage of the modelling process, particularly in biological systems where many parameters need to be estimated from sparse and noisy data sets. Over the years, a variety of heuristics have…

Quantitative Methods · Quantitative Biology 2011-11-07 Mariano Beguerisse-Diaz , Baojun Wang , Radhika Desikan , Mauricio Barahona

The range of applications of traditional optimization methods are limited by the features of the object variables, and of both the objective and the constraint functions. In contrast, population-based algorithms whose optimization…

Neural and Evolutionary Computing · Computer Science 2021-01-27 Mauro S. Innocente , Johann Sienz

Sampling multiple responses is a common way to improve LLM output quality, but it comes at the cost of additional computation. The key challenge is deciding when to stop generating new samples to balance accuracy gains against efficiency.…

Machine Learning · Computer Science 2025-10-21 Guangya Wan , Zixin Stephen Xu , Sasa Zorc , Manel Baucells , Mengxuan Hu , Hao Wang , Sheng Li

Systems that are based on recursive Bayesian updates for classification limit the cost of evidence collection through certain stopping/termination criteria and accordingly enforce decision making. Conventionally, two termination criteria…

Machine Learning · Computer Science 2021-04-27 Aziz Kocanaogullari , Murat Akcakaya , Deniz Erdogmus

Hidden Markov models (HMMs) are popular models to identify a finite number of latent states from sequential data. However, fitting them to large data sets can be computationally demanding because most likelihood maximization techniques…

Bayesian optimization (BO) is increasingly employed in critical applications to find the optimal design with minimal cost. While BO is known for its sample efficiency, relying solely on costly high-fidelity data can still result in high…

Artificial Intelligence · Computer Science 2025-03-25 Zahra Zanjani Foumani , Ramin Bostanabad

Predictive modelling is vital to guide preventive efforts. Whilst large-scale prospective cohort studies and a diverse toolkit of available machine learning (ML) algorithms have facilitated such survival task efforts, choosing the…

In this article we provide a comprehensive review of the different evolutionary algorithm techniques used to address multimodal optimization problems, classifying them according to the nature of their approach. On the one hand there are…

Neural and Evolutionary Computing · Computer Science 2015-08-24 Noe Casas

Video-based human pose estimation models aim to address scenarios that cannot be effectively solved by static image models such as motion blur, out-of-focus and occlusion. Most existing approaches consist of two stages: detecting human…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Zhihong Wei

Constrained multi-objective optimization problems (CMOPs) are of great significance in the context of practical applications, ranging from scientific to engineering domains. Most existing constrained multi-objective evolutionary algorithms…

Neural and Evolutionary Computing · Computer Science 2026-03-18 Shuai Shao , Ye Tian , Shangshang Yang , Xingyi Zhang

Diversity optimization is the class of optimization problems in which we aim to find a diverse set of good solutions. One of the frequently-used approaches to solve such problems is to use evolutionary algorithms that evolve a desired…

Neural and Evolutionary Computing · Computer Science 2025-12-17 Denis Antipov , Aneta Neumann , Frank Neumann , Andrew M. Sutton

A coreset is a subset of the training set, using which a machine learning algorithm obtains performances similar to what it would deliver if trained over the whole original data. Coreset discovery is an active and open line of research as…

Machine Learning · Computer Science 2020-02-21 Pietro Barbiero , Giovanni Squillero , Alberto Tonda

We present SEvoBench, a modern C++ framework for evolutionary computation (EC), specifically designed to systematically benchmark evolutionary single-objective optimization algorithms. The framework features modular implementations of…

Neural and Evolutionary Computing · Computer Science 2025-05-26 Yongkang Yang , Jian Zhao , Tengfei Yang