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Electronic Health Records (EHR) are generated from clinical routine care recording valuable information of broad patient populations, which provide plentiful opportunities for improving patient management and intervention strategies in…

Machine Learning · Computer Science 2023-04-13 Changshuo Liu , Wenqiao Zhang , Beng Chin Ooi , James Wei Luen Yip , Lingze Zeng , Kaiping Zheng

The volume estimation of brain regions from MRI data is a key problem in many clinical applications, where the acquisition of data at high spatial resolution is desirable. While parallel MRI and constrained image reconstruction algorithms…

Image and Video Processing · Electrical Eng. & Systems 2021-05-20 Aniket Pramanik , Xiaodong Wu , Mathews Jacob

Semantic segmentation of brain tumours is a fundamental task in medical image analysis that can help clinicians in diagnosing the patient and tracking the progression of any malignant entities. Accurate segmentation of brain lesions is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Aditya Kasliwal , Sankarshanaa Sagaram , Laven Srivastava , Pratinav Seth , Adil Khan

Recent advances in large multimodal models suggest that explicit reasoning mechanisms play a critical role in improving model reliability, interpretability, and cross-modal alignment. While such reasoning-centric approaches have been proven…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Tianjiao Yu , Xinzhuo Li , Yifan Shen , Yuanzhe Liu , Ismini Lourentzou

Due to the high stakes in medical decision-making, there is a compelling demand for interpretable deep learning methods in medical image analysis. Concept Bottleneck Models (CBM) have emerged as an active interpretable framework…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yibo Gao , Zheyao Gao , Xin Gao , Yuanye Liu , Bomin Wang , Xiahai Zhuang

Accurate lesion segmentation is essential in medical image analysis, yet most existing methods are designed for specific anatomical sites or imaging modalities, limiting their generalizability. Recent vision-language foundation models…

Image and Video Processing · Electrical Eng. & Systems 2026-03-30 Guoping Xu , Jayaram K. Udupa , Yubing Tong , Xin Long , Ying Zhang , Jie Deng , Weiguo Lu , You Zhang

Continual Structured Knowledge Reasoning (CSKR) focuses on training models to handle sequential tasks, where each task involves translating natural language questions into structured queries grounded in structured knowledge. Existing…

Computation and Language · Computer Science 2025-10-07 Yongrui Chen , Yi Huang , Yunchang Liu , Shenyu Zhang , Junhao He , Tongtong Wu , Guilin Qi , Tianxing Wu

We propose a dual pathway, 11-layers deep, three-dimensional Convolutional Neural Network for the challenging task of brain lesion segmentation. The devised architecture is the result of an in-depth analysis of the limitations of current…

Computer Vision and Pattern Recognition · Computer Science 2017-01-10 Konstantinos Kamnitsas , Christian Ledig , Virginia F. J. Newcombe , Joanna P. Simpson , Andrew D. Kane , David K. Menon , Daniel Rueckert , Ben Glocker

Explaining the decisions of Deep Neural Networks (DNNs) for medical images has become increasingly important. Existing attribution methods have difficulty explaining the meaning of pixels while existing concept-based methods are limited by…

Artificial Intelligence · Computer Science 2024-08-20 Weiji Kong , Xun Gong , Juan Wang

Precision medicine in the quantitative management of chronic diseases and oncology would be greatly improved if the Computed Tomography (CT) scan of any patient could be segmented, parsed and analyzed in a precise and detailed way. However,…

Recent advancements in deep learning-based interactive segmentation methods have significantly improved pathology image segmentation. Most existing approaches utilize user-provided positive and negative clicks to guide the segmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Tiantong Wang , Minfan Zhao , Jun Shi , Hannan Wang , Yue Dai

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Accurate medical image segmentation is fundamental to precision medicine, yet robust delineation remains challenging under heterogeneous appearances, ambiguous boundaries, and large anatomical variability. Similar intensity and texture…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Zhiquan Chen , Haitao Wang , Guowei Zou , Hejun Wu

Large language models achieve strong performance on many complex reasoning tasks, yet their accuracy degrades sharply on benchmarks that require compositional reasoning, including ARC-AGI-2, GPQA, MATH, BBH, and HLE. Existing methods…

Artificial Intelligence · Computer Science 2026-02-18 Sarim Chaudhry

Delineating anatomical regions is a key task in medical image analysis. Manual segmentation achieves high accuracy but is labor-intensive and prone to variability, thus prompting the development of automated approaches. Recently, a breadth…

Image and Video Processing · Electrical Eng. & Systems 2025-11-05 Alix de Langlais , Benjamin Billot , Théo Aguilar Vidal , Marc-Olivier Gauci , Hervé Delingette

Medical image segmentation is challenging due to overlapping anatomies with ambiguous boundaries and a severe imbalance between the foreground and background classes, which particularly affects the delineation of small lesions. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Hao Shao , Qibin Hou

Retrieving fine-grained visual content based on user intent remains a challenge in multi-modal systems. Although current Composed Image Retrieval (CIR) methods combine reference images with retrieval texts, they are constrained to…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Tong Wang , Guanyu Yang , Nian Liu , Zongyan Han , Jinxing Zhou , Salman Khan , Fahad Shahbaz Khan

Segmenting healthy tissue structures alongside lesions in brain Magnetic Resonance Images (MRI) remains a challenge for today's algorithms due to lesion-caused disruption of the anatomy and lack of jointly labeled training datasets, where…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Meva Himmetoglu , Ilja Ciernik , Ender Konukoglu

Medical image segmentation is crucial for clinical diagnosis, yet existing models are limited by their reliance on explicit human instructions and lack the active reasoning capabilities to understand complex clinical questions. While recent…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Yu Huang , Zelin Peng , Yichen Zhao , Piao Yang , Xiaokang Yang , Wei Shen

Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…