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The human microbiome plays critical roles in human health and has been linked to many diseases. While advanced sequencing technologies can characterize the composition of the microbiome in unprecedented detail, it remains challenging to…

We consider the complex data modeling problem motivated by the zero-inflated and overdispersed data from microbiome studies. Analyzing how microbiome abundance is associated with human biological features, such as BMI, is of great…

Methodology · Statistics 2025-03-31 Zirui Wang , Tianying Wang

Dimension reduction techniques are among the most essential analytical tools in the analysis of high-dimensional data. Generalized principal component analysis (PCA) is an extension to standard PCA that has been widely used to identify…

In this work we propose a novel approach for modeling spatio-temporal data characterized by group structures. In particular, we extend classical mixed effect regression models by introducing a space-time nonparametric component, regularized…

Methodology · Statistics 2025-11-18 Marco F. De Sanctis , Eleonora Arnone , Francesca Ieva , Laura M. Sangalli

This work presents a sum-of-squares (SOS) based framework to perform data-driven stabilization and robust control tasks on discrete-time linear systems where the full-state observations are corrupted by L-infinity bounded input,…

Optimization and Control · Mathematics 2023-03-31 Jared Miller , Tianyu Dai , Mario Sznaier

A folded type model is developed for analyzing compositional data. The proposed model involves an extension of the $\alpha$-transformation for compositional data and provides a new and flexible class of distributions for modeling data…

Machine Learning · Statistics 2019-02-27 Michail Tsagris , Connie Stewart

Discrete data such as counts of microbiome taxa resulting from next-generation sequencing are routinely encountered in bioinformatics. Taxa count data in microbiome studies are typically high-dimensional, over-dispersed, and can only reveal…

Methodology · Statistics 2022-06-23 Yuan Fang , Sanjeena Subedi

The increasing availability of passively observed data has yielded a growing methodological interest in "data fusion." These methods involve merging data from observational and experimental sources to draw causal conclusions -- and they…

Methodology · Statistics 2021-12-15 Evan Rosenman , Art B. Owen

This monograph introduces a novel approach to polyphonic music generation by addressing the "Missing Middle" problem through structural inductive bias. Focusing on Beethoven's piano sonatas as a case study, we empirically verify the…

Machine Learning · Computer Science 2026-04-10 Joonwon Seo

This paper addresses the task of zero-shot image classification. The key contribution of the proposed approach is to control the semantic embedding of images -- one of the main ingredients of zero-shot learning -- by formulating it as a…

Computer Vision and Pattern Recognition · Computer Science 2016-07-28 Maxime Bucher , Stéphane Herbin , Frédéric Jurie

Most practical data science problems encounter missing data. A wide variety of solutions exist, each with strengths and weaknesses that depend upon the missingness-generating process. Here we develop a theoretical framework for training and…

Machine Learning · Computer Science 2022-11-15 Jahan C. Penny-Dimri , Christoph Bergmeir , Julian Smith

We propose a systematic method to directly identify a sensor fault estimation filter from plant input/output data collected under fault-free condition. This problem is challenging, especially when omitting the step of building an explicit…

Systems and Control · Computer Science 2015-05-11 Yiming Wan , Tamas Keviczky , Michel Verhaegen

The quality of numerical reconstructions for unknown parameters in inverse problems depends fundamentally on the selection of experimental data. To ensure a robust reconstruction, it is crucial to select data that are sensitive to the…

Numerical Analysis · Mathematics 2026-04-14 Kathrin Hellmuth , Christian Klingenberg , Qin Li

The paper revisits the $\alpha$--regression framework for compositional data. The model uses a flexible power transformation parameterized by $\alpha$ to interpolate between raw data analysis and log--ratio methods, naturally handling zeros…

Methodology · Statistics 2026-05-14 Michail Tsagris , Yannis Pantazis

Compositional data analysis is carried out either by neglecting the compositional constraint and applying standard multivariate data analysis, or by transforming the data using the logs of the ratios of the components. In this work we…

Methodology · Statistics 2011-06-17 Michail T. Tsagris , Simon Preston , Andrew T. A. Wood

Conformal inference is a statistical method used to construct prediction sets for point predictors, providing reliable uncertainty quantification with probability guarantees. This method utilizes historical labeled data to estimate the…

Machine Learning · Computer Science 2024-11-05 Xiaoyi Su , Zhixin Zhou , Rui Luo

Panel data of our interest consist of a moderate or relatively large number of panels, while the panels contain a small number of observations. This paper establishes testing procedures to detect a possible common change in means of the…

Statistics Theory · Mathematics 2016-08-07 Barbora Peštová , Michal Pešta

Existing effect measures for compositional features are inadequate for many modern applications, for example, in microbiome research, since they display traits such as high-dimensionality and sparsity that can be poorly modelled with…

Methodology · Statistics 2025-06-02 Anton Rask Lundborg , Niklas Pfister

In human microbiome studies, sequencing reads data are often summarized as counts of bacterial taxa at various taxonomic levels specified by a taxonomic tree. This paper considers the problem of analyzing two repeated measurements of…

Applications · Statistics 2017-02-17 Pixu Shi , Hongzhe Li

Multivariate categorical data nested within households often include reported values that fail edit constraints---for example, a participating household reports a child's age as older than his biological parent's age---as well as missing…

Methodology · Statistics 2018-09-21 Olanrewaju Akande , Andrés Barrientos , Jerome P. Reiter
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