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Digital Twins hold great potential to personalize clinical patient care, provided the concept is translated to meet specific requirements emerging from established clinical workflows. We present a general and unspecialized Digital Twin…
Digital twin technology has is anticipated to transform healthcare, enabling personalized medicines and support, earlier diagnoses, simulated treatment outcomes, and optimized surgical plans. Digital twins are readily gaining traction in…
Emerging from NASA's spacecraft simulations in the 1960s, digital twin technology has advanced through industrial adoption to spark a healthcare transformation. A digital twin is a dynamic, data-driven virtual counterpart of a physical…
We propose a digital twin approach to improve healthcare decision support systems with a combination of domain knowledge and data. Domain knowledge helps build decision thresholds that doctors can use to determine a risk or recommend a…
Colorectal cancer, inflammatory bowel disease, and diverticular disease are progressive conditions that affect millions of individuals worldwide and impose substantial clinical and economic burdens. Early detection and personalized…
A cardiac digital twin is a virtual replica of a patient's heart for screening, diagnosis, prognosis, risk assessment, and treatment planning of cardiovascular diseases. This requires an anatomically accurate patient-specific 3D structural…
Recently, significant efforts have been made to create Health Digital Twins (HDTs), digital twins for clinical applications. Heart modeling is one of the fastest-growing fields, which favors the effective application of HDTs. The clinical…
Artificial Intelligence (AI) and Large Language Models (LLMs) hold significant promise in revolutionizing healthcare, especially in clinical applications. Simultaneously, Digital Twin technology, which models and simulates complex systems,…
A cardiac digital twin is a virtual replica of a patient-specific heart, mimicking its anatomy and physiology. A crucial step of building a cardiac digital twin is anatomical twinning, where the computational mesh of the digital twin is…
A digital twin is a virtual replica of a real-world physical phenomena that uses mathematical modeling to characterize and simulate its defining features. By constructing digital twins for disease processes, we can perform in-silico…
The digital twin concept represents an appealing opportunity to advance condition-based and predictive maintenance paradigms for civil engineering systems, thus allowing reduced lifecycle costs, increased system safety, and increased system…
A patient's digital twin is a computational model that describes the evolution of their health over time. Digital twins have the potential to revolutionize medicine by enabling individual-level computer simulations of human health, which…
A digital health twin can be defined as a virtual model of a physical person, in this specific case, a patient. This virtual model is constituted by multidimensional data that can host from clinical, molecular and therapeutic parameters to…
Chronic diseases constitute the principal burden of morbidity, mortality, and healthcare costs worldwide, yet current health systems remain fragmented and predominantly reactive. Patient Medical Digital Twins (PMDTs) offer a paradigm shift:…
Medical imaging has played a pivotal role in advancing and refining digital twin technology, allowing for the development of highly personalized virtual models that represent human anatomy and physiological functions. A key component in…
Heart diseases rank among the leading causes of global mortality, demonstrating a crucial need for early diagnosis and intervention. Most traditional electrocardiogram (ECG) based automated diagnosis methods are trained at population level,…
Quantifying the uncertainty in predictive models is critical for establishing trust and enabling risk-informed decision making for personalized medicine. In contrast to one-size-fits-all approaches that seek to mitigate risk at the…
Background and Objective: Precise preoperative planning and effective physician training for coronary interventions are increasingly important. Despite advances in medical imaging technologies, transforming static or limited dynamic imaging…
Cardiac arrest is one of the biggest global health problems, and early identification and management are key to enhancing the patient's prognosis. In this paper, we propose a novel framework that combines an EfficientNet-based deep learning…
We propose a synthesis method for the design of digital twins applicable to various systems (pneumatic, hydraulic, electrical/electronic circuits). The methodology allows representing the operation of these systems through an active digital…