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Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Xiangde Luo , Jinxi Xiang , Yuanfeng Ji , Ruijiang Li

Liver cancer has a high incidence rate, but primary healthcare settings often lack experienced doctors. Advances in large models and AI technologies offer potential assistance. This work aims to address limitations in liver cancer diagnosis…

Medical Physics · Physics 2024-06-27 Xuzhou Wu , Guangxin Li , Xing Wang , Zeyu Xu , Yingni Wang , Jianming Xian , Xueyu Wang , Gong Li , Kehong Yuan

Fine-grained glomerular subtyping is central to kidney biopsy interpretation, but clinically valuable labels are scarce and difficult to obtain. Existing computational pathology approaches instead tend to evaluate coarse diseased…

Lymphoma diagnosis, particularly distinguishing between subtypes, is critical for effective treatment but remains challenging due to the subtle morphological differences in histopathological images. This study presents a novel hybrid deep…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Salah A. Aly , Ali Bakhiet , Mazen Balat

Health management has become a primary problem as new kinds of diseases and complex symptoms are introduced to a rapidly growing modern society. Building a better and smarter healthcare infrastructure is one of the ultimate goals of a smart…

Machine Learning · Computer Science 2025-03-24 Chu Myaet Thwal , Kyi Thar , Ye Lin Tun , Choong Seon Hong

Liver cancer is a leading cause of cancer-related mortality worldwide, with its high genetic heterogeneity complicating diagnosis and treatment. This study introduces DLSOM, a deep learning framework utilizing stacked autoencoders to…

Genomics · Quantitative Biology 2024-12-18 Fabio Zamio

A mutation in the DNA of a single cell that compromises its function initiates leukemia,leading to the overproduction of immature white blood cells that encroach upon the space required for the generation of healthy blood cells.Leukemia is…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Md. Abu Ahnaf Mollick , Md. Mahfujur Rahman , D. M. Asadujjaman , Abdullah Tamim , Nosin Anjum Dristi , Md. Takbir Hossen

Deep learning models are favored in many research and industry areas and have reached the accuracy of approximating or even surpassing human level. However they've long been considered by researchers as black-box models for their…

Machine Learning · Computer Science 2020-10-16 Xiaojian Wang , Jingyuan Wang , Ke Tang

Liver fibrosis poses a substantial challenge in clinical practice, emphasizing the necessity for precise liver segmentation and accurate disease staging. Based on the CARE Liver 2025 Track 4 Challenge, this study introduces a multi-task…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Boya Wang , Ruizhe Li , Chao Chen , Xin Chen

Staging of liver fibrosis is important in the diagnosis and treatment planning of patients suffering from liver diseases. Current deep learning-based methods using abdominal magnetic resonance imaging (MRI) usually take a sub-region of the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Zheyao Gao , Yuanye Liu , Fuping Wu , NanNan Shi , Yuxin Shi , Xiahai Zhuang

Clinical oncology generates vast, unstructured data that often contain inconsistencies, missing information, and ambiguities, making it difficult to extract reliable insights for data-driven decision-making. General-purpose large language…

Computation and Language · Computer Science 2025-03-12 Morteza Rohanian , Tarun Mehra , Nicola Miglino , Farhad Nooralahzadeh , Michael Krauthammer , Andreas Wicki

Determining lymphoma subtypes is a crucial step for better patient treatment targeting to potentially increase their survival chances. In this context, the existing gold standard diagnosis method, which relies on gene expression technology,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Bilel Guetarni , Feryal Windal , Halim Benhabiles , Marianne Petit , Romain Dubois , Emmanuelle Leteurtre , Dominique Collard

Liver infection is a common disease, which poses a great threat to human health, but there is still able to identify an optimal technique that can be used on large-level screening. This paper deals with ML algorithms using different data…

Machine Learning · Computer Science 2023-05-16 P. Deivendran , S. Selvakanmani , S. Jegadeesan , V. Vinoth Kumar

The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale…

Machine Learning · Computer Science 2026-04-07 Yaxin Xu , Yue Zhou , Tianyu Zhao , Fengwei An , Zhixiang Ren

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jinliang Yu , Mingduo Xie , Yue Wang , Tianfan Fu , Xianglai Xu , Jiajun Wang

Accurate survival prediction in Non-Small Cell Lung Cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal Deep Learning (MDL) can improve precision prognosis, but small cohorts and missing…

Clinical abnormality grounding for rare diseases is often hindered by data scarcity, making supervised fine-tuning impractical and single-pass inference highly unstable. We propose Dynamic Decision Learning (DDL), a framework that enables…

Computation and Language · Computer Science 2026-04-29 Jun Li , Mingxuan Liu , Jiazhen Pan , Che Liu , Wenjia Bai , Cosmin I. Bercea , Julia A. Schnabel

Computational phenotyping is a central informatics activity with resulting cohorts supporting a wide variety of applications. However, it is time-intensive because of manual data review and limited automation. Since LLMs have demonstrated…

Quantitative Methods · Quantitative Biology 2025-08-18 Sarah Pungitore , Shashank Yadav , Molly Douglas , Jarrod Mosier , Vignesh Subbian

Multiple Sclerosis (MS) is a chronic disease developed in human brain and spinal cord, which can cause permanent damage or deterioration of the nerves. The severity of MS disease is monitored by the Expanded Disability Status Scale (EDSS),…

Machine Learning · Computer Science 2023-04-11 Kai Zhang , John A. Lincoln , Xiaoqian Jiang , Elmer V. Bernstam , Shayan Shams