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Segment Anything Model 2 (SAM2) demonstrated impressive zero-shot capabilities on natural images but faces challenges in biomedical segmentation due to significant domain shifts and prompt dependency. To address these limitations, we…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Hinako Mitsuoka , Kazuhiro Hotta

The recently released Segment Anything Model (SAM) has shown powerful zero-shot segmentation capabilities through a semi-automatic annotation setup in which the user can provide a prompt in the form of clicks or bounding boxes. There is…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Benjamin Towle , Xin Chen , Ke Zhou

Surgical image segmentation is highly challenging, primarily due to scarcity of annotated data. Generalist prompted segmentation models like the Segment-Anything Model (SAM) can help tackle this task, but because they require image-specific…

Computer Vision and Pattern Recognition · Computer Science 2025-07-16 Aditya Murali , Farahdiba Zarin , Adrien Meyer , Pietro Mascagni , Didier Mutter , Nicolas Padoy

Deep learning based methods often suffer from performance degradation caused by domain shift. In recent years, many sophisticated network structures have been designed to tackle this problem. However, the advent of large model trained on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Zhikai Wei , Wenhui Dong , Peilin Zhou , Yuliang Gu , Zhou Zhao , Yongchao Xu

The Segment Anything Model (SAM) is a powerful foundation model for image segmentation, showing robust zero-shot generalization through prompt engineering. However, relying on manual prompts is impractical for real-world applications,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Yi Chen , Mu-Young Son , Chuanbo Hua , Joo-Young Kim

With the proposal of the Segment Anything Model (SAM), fine-tuning SAM for medical image segmentation (MIS) has become popular. However, due to the large size of the SAM model and the significant domain gap between natural and medical…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Jinfeng Wang , Sifan Song , Xinkun Wang , Yiyi Wang , Yiyi Miao , Jionglong Su , S. Kevin Zhou

The Segment Anything Model (SAM) has exhibited outstanding performance in various image segmentation tasks. Despite being trained with over a billion masks, SAM faces challenges in mask prediction quality in numerous scenarios, especially…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhaozhi Xie , Bochen Guan , Weihao Jiang , Muyang Yi , Yue Ding , Hongtao Lu , Lei Zhang

Despite the remarkable success of deep learning in medical imaging analysis, medical image segmentation remains challenging due to the scarcity of high-quality labeled images for supervision. Further, the significant domain gap between…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Hedda Cohen Indelman , Elay Dahan , Angeles M. Perez-Agosto , Carmit Shiran , Doron Shaked , Nati Daniel

Leveraging pre-trained models with tailored prompts for in-context learning has proven highly effective in NLP tasks. Building on this success, recent studies have applied a similar approach to the Segment Anything Model (SAM) within a…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Hangyul Yoon , Doohyuk Jang , Jungeun Kim , Eunho Yang

Accurate organ segmentation is essential for clinical tasks such as radiotherapy planning and disease monitoring. Recent foundation models like MedSAM achieve strong results using point or bounding-box prompts but still require manual…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Wenjie Zhang , Liming Luo , Mengnan He , Jiarui Hai , Jiancheng Ye

Accurate tongue segmentation is crucial for reliable TCM analysis. Supervised models require large annotated datasets, while SAM-family models remain prompt-driven. We present Memory-SAM, a training-free, human-prompt-free pipeline that…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Joongwon Chae , Lihui Luo , Xi Yuan , Dongmei Yu , Zhenglin Chen , Lian Zhang , Peiwu Qin

In digital pathology, precise nuclei segmentation is pivotal yet challenged by the diversity of tissue types, staining protocols, and imaging conditions. Recently, the segment anything model (SAM) revealed overwhelming performance in…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Zhen Chen , Qing Xu , Xinyu Liu , Yixuan Yuan

Diffusion models have shown impressive performance for generative modelling of images. In this paper, we present a novel semantic segmentation method based on diffusion models. By modifying the training and sampling scheme, we show that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe Valmaggia , Philippe C. Cattin

Foundation models, such as the Segment Anything Model (SAM), have heightened interest in promptable zero-shot segmentation. Although these models perform strongly on natural images, their behavior on medical data remains insufficiently…

Image and Video Processing · Electrical Eng. & Systems 2026-04-07 Satrajit Chakrabarty , Ravi Soni

Segmentation is a fundamental problem in surgical scene analysis using artificial intelligence. However, the inherent data scarcity in this domain makes it challenging to adapt traditional segmentation techniques for this task. To tackle…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Jay N. Paranjape , Nithin Gopalakrishnan Nair , Shameema Sikder , S. Swaroop Vedula , Vishal M. Patel

The Segment Anything Model (SAM) and similar models build a family of promptable foundation models (FMs) for image and video segmentation. The object of interest is identified using prompts, such as bounding boxes or points. With these FMs…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Caroline Magg , Hoel Kervadec , Clara I. Sánchez

Foundation models have taken over natural language processing and image generation domains due to the flexibility of prompting. With the recent introduction of the Segment Anything Model (SAM), this prompt-driven paradigm has entered image…

Image and Video Processing · Electrical Eng. & Systems 2023-04-13 Saikat Roy , Tassilo Wald , Gregor Koehler , Maximilian R. Rokuss , Nico Disch , Julius Holzschuh , David Zimmerer , Klaus H. Maier-Hein

Recent advancements in deep learning for medical image segmentation are often limited by the scarcity of high-quality training data.While diffusion models provide a potential solution by generating synthetic images, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Jianhao Xie , Ziang Zhang , Zhenyu Weng , Yuesheng Zhu , Guibo Luo

This paper provides insights on the effectiveness of the zero shot, prompt-based Segment Anything Model (SAM) and its updated versions, SAM 2 and SAM 2.1, along with the non-promptable conventional neural network (CNN), for segmenting solar…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Osher Rafaeli , Tal Svoray , Roni Blushtein-Livnon , Ariel Nahlieli

The segment anything model (SAM) was released as a foundation model for image segmentation. The promptable segmentation model was trained by over 1 billion masks on 11M licensed and privacy-respecting images. The model supports zero-shot…