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Glaucoma is a major eye disease, leading to vision loss in the absence of proper medical treatment. Current diagnosis of glaucoma is performed by ophthalmologists who are often analyzing several types of medical images generated by…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Mijung Kim , Olivier Janssens , Ho-min Park , Jasper Zuallaert , Sofie Van Hoecke , Wesley De Neve

Using histopathological images to automatically classify cancer is a difficult task for accurately detecting cancer, especially to identify metastatic cancer in small image patches obtained from larger digital pathology scans. Computer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Guanwen Qiu , Xiaobing Yu , Baolin Sun , Yunpeng Wang , Lipei Zhang

The 7-point checklist (7PCL) is a widely used diagnostic tool in dermoscopy for identifying malignant melanoma by assigning point values to seven specific attributes. However, the traditional 7PCL is limited to distinguishing between…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Yuheng Wang , Tianze Yu , Jiayue Cai , Sunil Kalia , Harvey Lui , Z. Jane Wang , Tim K. Lee

Over the past decade, cryogenic electron microscopy (cryo-EM) has emerged as a primary method for determining near-native, near-atomic resolution 3D structures of biological macromolecules. In order to meet increasing demand for cryo-EM,…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Paul T. Kim , Alex J. Noble , Anchi Cheng , Tristan Bepler

Summary: Accurate phenotype prediction from genomic sequences is a highly coveted task in biological and medical research. While machine-learning holds the key to accurate prediction in a variety of fields, the complexity of biological data…

Automated Machine Learning (AutoML) is used more than ever before to support users in determining efficient hyperparameters, neural architectures, or even full machine learning pipelines. However, users tend to mistrust the optimization…

Machine Learning · Computer Science 2022-07-12 René Sass , Eddie Bergman , André Biedenkapp , Frank Hutter , Marius Lindauer

Epigenetics encompasses mechanisms that can alter the expression of genes without changing the underlying genetic sequence. The epigenetic regulation of gene expression is initiated and sustained by several mechanisms such as DNA…

Genomics · Quantitative Biology 2025-04-08 Muhammad Tahir , Mahboobeh Norouzi , Shehroz S. Khan , James R. Davie , Soichiro Yamanaka , Ahmed Ashraf

Artificial intelligence-enhanced identification of organs, lesions, and other structures in medical imaging is typically done using convolutional neural networks (CNNs) designed to make voxel-accurate segmentations of the region of…

De-identification of medical images is a critical step to ensure privacy during data sharing in research and clinical settings. The initial step in this process involves detecting Protected Health Information (PHI), which can be found in…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Tuan Truong , Ivo M. Baltruschat , Mark Klemens , Grit Werner , Matthias Lenga

Melanoma is a prevalent lethal type of cancer that is treatable if diagnosed at early stages of development. Skin lesions are a typical indicator for diagnosing melanoma but they often led to delayed diagnosis due to high similarities of…

Machine Learning · Computer Science 2023-03-28 Ruitong Sun , Mohammad Rostami

Nowadays, cardiac diagnosis largely depends on left ventricular function assessment. With the help of the segmentation deep learning model, the assessment of the left ventricle becomes more accessible and accurate. However, deep learning…

Computer Vision and Pattern Recognition · Computer Science 2021-10-29 Hang Duong Thi Thuy , Tuan Nguyen Minh , Phi Nguyen Van , Long Tran Quoc

Multiple myeloma cancer is a type of blood cancer that happens when the growth of abnormal plasma cells becomes out of control in the bone marrow. There are various ways to diagnose multiple myeloma in bone marrow such as complete blood…

Image and Video Processing · Electrical Eng. & Systems 2021-05-14 Afshin Bozorgpour , Reza Azad , Eman Showkatian , Alaa Sulaiman

Bone marrow cell cytomorphology analysis is critical for the diagnosis of hematological malignancies but remains a labor-intensive process subject to significant inter-observer variability. While recent foundation models have shown promise…

Other Quantitative Biology · Quantitative Biology 2025-12-23 Aziz Muminov , Anne Pham

Analyzing atomically resolved images is a time-consuming process requiring solid experience and substantial human intervention. In addition, the acquired images contain a large amount of information such as crystal structure, presence and…

Proteins are the main workhorses of biological functions in a cell, a tissue, or an organism. Identification and quantification of proteins in a given sample, e.g. a cell type under normal/disease conditions, are fundamental tasks for the…

Computational Engineering, Finance, and Science · Computer Science 2017-10-10 Ngoc Hieu Tran , Zachariah Levine , Lei Xin , Baozhen Shan , Ming Li

CR-39 solid-state nuclear track detectors are widely used in fusion research for detecting charged particles produced in fusion reactions. However, analyzing increasingly complex and large-scale CR-39 track images to extract meaningful…

Instrumentation and Detectors · Physics 2025-05-13 Yuxing Wang , Allan Xi Chen , Matthew Salazar , Nawar Abdalla , Zhifei Li , Benjamin Wrixon

Cervical cancer remains a significant health challenge, with high incidence and mortality rates, particularly in transitioning countries. Conventional Liquid-Based Cytology(LBC) is a labor-intensive process, requires expert pathologists and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Love Panta , Suraj Prasai , Karishma Malla Vaidya , Shyam Shrestha , Suresh Manandhar

Acute Myeloid Leukemia (AML) is one of the most life-threatening type of blood cancers, and its accurate classification is considered and remains a challenging task due to the visual similarity between various cell types. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Enas E. Ahmed , Salah A. Aly , Mayar Moner

Methods for evaluating the quality of genomic and metagenomic data are essential to aid genome assembly and to correctly interpret the results of subsequent analyses. BUSCO estimates the completeness and redundancy of processed genomic data…

Genomics · Quantitative Biology 2021-06-23 Mosè Manni , Matthew R Berkeley , Mathieu Seppey , Felipe A Simao , Evgeny M Zdobnov

We introduce YATO, an open-source, easy-to-use toolkit for text analysis with deep learning. Different from existing heavily engineered toolkits and platforms, YATO is lightweight and user-friendly for researchers from cross-disciplinary…

Computation and Language · Computer Science 2023-10-19 Zeqiang Wang , Yile Wang , Jiageng Wu , Zhiyang Teng , Jie Yang
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