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In this paper, we address the segmentation of tumor subtypes in whole slide images (WSI) by utilizing incomplete label proportions. Specifically, we utilize `partial' label proportions, which give the proportions among tumor subtypes but do…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Shinnosuke Matsuo , Daiki Suehiro , Seiichi Uchida , Hiroaki Ito , Kazuhiro Terada , Akihiko Yoshizawa , Ryoma Bise

Weakly-supervised learning (WSL) has recently triggered substantial interest as it mitigates the lack of pixel-wise annotations. Given global image labels, WSL methods yield pixel-level predictions (segmentations), which enable to interpret…

Computer Vision and Pattern Recognition · Computer Science 2021-10-12 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Weakly supervised semantic segmentation (WSSS) in histopathology reduces pixel-level labeling by learning from image-level labels, but it is hindered by inter-class homogeneity, intra-class heterogeneity, and CAM-induced region shrinkage…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Khang Le , Anh Mai Vu , Thi Kim Trang Vo , Ha Thach , Ngoc Bui Lam Quang , Thanh-Huy Nguyen , Minh H. N. Le , Zhu Han , Chandra Mohan , Hien Van Nguyen

Tissue-level semantic segmentation is a vital step in computational pathology. Fully-supervised models have already achieved outstanding performance with dense pixel-level annotations. However, drawing such labels on the giga-pixel whole…

Image and Video Processing · Electrical Eng. & Systems 2021-10-18 Chu Han , Jiatai Lin , Jinhai Mai , Yi Wang , Qingling Zhang , Bingchao Zhao , Xin Chen , Xipeng Pan , Zhenwei Shi , Xiaowei Xu , Su Yao , Lixu Yan , Huan Lin , Zeyan Xu , Xiaomei Huang , Guoqiang Han , Changhong Liang , Zaiyi Liu

In recent years, Fine-Grained Visual Classification (FGVC) has achieved impressive recognition accuracy, despite minimal inter-class variations. However, existing methods heavily rely on instance-level labels, making them impractical in…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Jinyi Chang , Dongliang Chang , Lei Chen , Bingyao Yu , Zhanyu Ma

Image segmentation is a critical step in computational biomedical image analysis, typically evaluated using metrics like the Dice coefficient during training and validation. However, in clinical settings without manual annotations,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Sikha O K , Meritxell Riera-Marín , Adrian Galdran , Javier García Lopez , Julia Rodríguez-Comas , Gemma Piella , Miguel A. González Ballester

Evaluating the regeneration process of damaged muscle tissue is a fundamental analysis in muscle research to measure experimental effect sizes and uncover mechanisms behind muscle weakness due to aging and disease. The conventional approach…

Computer Vision and Pattern Recognition · Computer Science 2025-05-09 Yu Yamaoka , Weng Ian Chan , Shigeto Seno , Soichiro Fukada , Hideo Matsuda

We investigate Learning from Label Proportions (LLP), a partial information setting where examples in a training set are grouped into bags, and only aggregate label values in each bag are available. Despite the partial observability, the…

Machine Learning · Computer Science 2025-06-02 Robert Busa-Fekete , Travis Dick , Claudio Gentile , Haim Kaplan , Tomer Koren , Uri Stemmer

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

Analysis of histopathology slides is a critical step for many diagnoses, and in particular in oncology where it defines the gold standard. In the case of digital histopathological analysis, highly trained pathologists must review vast…

Computer Vision and Pattern Recognition · Computer Science 2020-02-21 Pierre Courtiol , Eric W. Tramel , Marc Sanselme , Gilles Wainrib

Semantic segmentation of various tissue and nuclei types in histology images is fundamental to many downstream tasks in the area of computational pathology (CPath). In recent years, Deep Learning (DL) methods have been shown to perform well…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Raja Muhammad Saad Bashir , Talha Qaiser , Shan E Ahmed Raza , Nasir M. Rajpoot

In digital pathology, segmenting densely distributed objects like glands and nuclei is crucial for downstream analysis. Since detailed pixel-wise annotations are very time-consuming, we need semi-supervised segmentation methods that can…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 Meilong Xu , Xiaoling Hu , Saumya Gupta , Shahira Abousamra , Chao Chen

Weakly supervised semantic segmentation is a challenging task as it only takes image-level information as supervision for training but produces pixel-level predictions for testing. To address such a challenging task, most recent…

Computer Vision and Pattern Recognition · Computer Science 2019-11-20 Bingfeng Zhang , Jimin Xiao , Yunchao Wei , Mingjie Sun , Kaizhu Huang

Semi-supervised semantic segmentation requires the model to effectively propagate the label information from limited annotated images to unlabeled ones. A challenge for such a per-pixel prediction task is the large intra-class variation,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Hai-Ming Xu , Lingqiao Liu , Qiuchen Bian , Zhen Yang

Trained using only image class label, deep weakly supervised methods allow image classification and ROI segmentation for interpretability. Despite their success on natural images, they face several challenges over histology data where ROI…

Image and Video Processing · Electrical Eng. & Systems 2022-05-13 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Segmentation is a key stage in dermoscopic image processing, where the accuracy of the border line that defines skin lesions is of utmost importance for subsequent algorithms (e.g., classification) and computer-aided early diagnosis of…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Pedro M. M. Pereira , Rui Fonseca-Pinto , Rui Pedro Paiva , Luis M. N. Tavora , Pedro A. A. Assuncao , Sergio M. M. de Faria

Learning from Label Proportions (LLP) is a weakly supervised learning method that aims to perform instance classification from training data consisting of pairs of bags containing multiple instances and the class label proportions within…

Machine Learning · Computer Science 2023-02-22 Ryoma Kobayashi , Yusuke Mukuta , Tatsuya Harada

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Automatic histopathology image segmentation is crucial to disease analysis. Limited available labeled data hinders the generalizability of trained models under the fully supervised setting. Semi-supervised learning (SSL) based on generative…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Hongxiao Wang , Hao Zheng , Jianxu Chen , Lin Yang , Yizhe Zhang , Danny Z. Chen

The task of image segmentation is inherently noisy due to ambiguities regarding the exact location of boundaries between anatomical structures. We argue that this information can be extracted from the expert annotations at no extra cost,…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Mobarakol Islam , Ben Glocker
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