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While large language models hold promise for complex medical applications, their development is hindered by the scarcity of high-quality reasoning data. To address this issue, existing approaches typically distill chain-of-thought reasoning…

Machine Learning · Computer Science 2026-04-14 Haolin Li , Shuyang Jiang , Ruipeng Zhang , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Medical Decision-Making (MDM) is a complex process requiring substantial domain-specific expertise to effectively synthesize heterogeneous and complicated clinical information. While recent advancements in Large Language Models (LLMs) show…

Artificial Intelligence · Computer Science 2025-08-20 Liuxin Bao , Zhihao Peng , Xiaofei Zhou , Runmin Cong , Jiyong Zhang , Yixuan Yuan

Recent advances in large language models (LLMs) have enabled molecular reasoning for property prediction. However, toxicity arises from complex biological mechanisms beyond chemical structure, necessitating mechanistic reasoning for…

Quantitative Methods · Quantitative Biology 2026-04-09 Jueon Park , Wonjune Jang , Chanhwi Kim , Yein Park , Jaewoo Kang

Multimodal misinformation floods on various social media, and continues to evolve in the era of AI-generated content (AIGC). The emerged misinformation with low creation cost and high deception poses significant threats to society. While…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Junjie Wu , Guohong Fu

Large Language Models (LLMs) with reasoning capabilities have recently demonstrated strong potential in medical Question Answering (QA). Existing approaches are largely English-focused and primarily rely on distillation from general-purpose…

Computation and Language · Computer Science 2026-03-31 Pietro Ferrazzi , Aitor Soroa , Rodrigo Agerri

In this paper, we argue that the design and development of multimodal datasets for natural language processing (NLP) challenges should be enhanced in two significant respects: to more broadly represent commonsense semantic inferences; and…

Computation and Language · Computer Science 2021-05-14 James Pustejovsky , Eben Holderness , Jingxuan Tu , Parker Glenn , Kyeongmin Rim , Kelley Lynch , Richard Brutti

In this paper, we present a novel diagnostic framework that integrates Knowledge Graphs (KGs) and Large Language Models (LLMs) to support system diagnostics in high-reliability systems such as nuclear power plants. Traditional diagnostic…

Artificial Intelligence · Computer Science 2025-09-01 Saman Marandi , Yu-Shu Hu , Mohammad Modarres

Logical reasoning is a fundamental aspect of human intelligence and an essential capability for multimodal large language models (MLLMs). Despite the significant advancement in multimodal reasoning, existing benchmarks fail to…

Artificial Intelligence · Computer Science 2025-05-28 Jiakang Yuan , Tianshuo Peng , Yilei Jiang , Yiting Lu , Renrui Zhang , Kaituo Feng , Chaoyou Fu , Tao Chen , Lei Bai , Bo Zhang , Xiangyu Yue

Large language models (LLMs) perform strongly on many language tasks but still struggle with complex multi-step reasoning across disciplines. Existing reasoning datasets often lack disciplinary breadth, reasoning depth, and diversity, as…

Computation and Language · Computer Science 2026-02-03 Weize Liu , Yongchi Zhao , Yijia Luo , Mingyu Xu , Jiaheng Liu , Yanan Li , Xiguo Hu , Zhiqi Bai , Yuchi Xu , Wenbo Su , Bo Zheng

As the field of healthcare increasingly adopts artificial intelligence, it becomes important to understand which types of explanations increase transparency and empower users to develop confidence and trust in the predictions made by…

Artificial Intelligence · Computer Science 2025-05-16 Felix Liedeker , Olivia Sanchez-Graillet , Moana Seidler , Christian Brandt , Jörg Wellmer , Philipp Cimiano

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Analogical reasoning, particularly in multimodal contexts, is the foundation of human perception and creativity. Multimodal Large Language Model (MLLM) has recently sparked considerable discussion due to its emergent capabilities. In this…

Computation and Language · Computer Science 2024-11-05 Diandian Guo , Cong Cao , Fangfang Yuan , Dakui Wang , Wei Ma , Yanbing Liu , Jianhui Fu

Large Language Models (LLMs) employing Chain-of-Thought (CoT) prompting have broadened the scope for improving multi-step reasoning capabilities. We generally divide multi-step reasoning into two phases: path generation to generate the…

Computation and Language · Computer Science 2024-08-20 Shumin Deng , Ningyu Zhang , Nay Oo , Bryan Hooi

Large language models (LLMs), while promising, face criticisms for biases, hallucinations, and a lack of reasoning capability. This paper introduces SocraSynth, a multi-LLM agent reasoning platform developed to mitigate these issues.…

Artificial Intelligence · Computer Science 2024-02-13 Edward Y. Chang

Extracting structured information from clinical notes requires navigating a dense web of interdependent variables where the value of one attribute logically constrains others. Existing Large Language Model (LLM)-based extraction pipelines…

Large Language Models (LLMs) have succeeded remarkably in various natural language processing (NLP) tasks, yet their reasoning capabilities remain a fundamental challenge. While LLMs exhibit impressive fluency and factual recall, their…

Computation and Language · Computer Science 2025-05-29 Avinash Patil , Aryan Jadon

An integrated approach is proposed across visual and textual data to both determine and justify a medical diagnosis by a neural network. As deep learning techniques improve, interest grows to apply them in medical applications. To enable a…

Machine Learning · Computer Science 2019-07-15 Graham Spinks , Marie-Francine Moens

Although large multimodal models (LMMs) have demonstrated remarkable capabilities in visual scene interpretation and reasoning, their capacity for complex and precise 3-dimensional spatial reasoning remains uncertain. Existing benchmarks…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Xingrui Wang , Wufei Ma , Tiezheng Zhang , Celso M de Melo , Jieneng Chen , Alan Yuille

Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with language context for comprehensive diagnostic analysis. These…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Zhe Xu , Ziyi Liu , Junlin Hou , Jiabo Ma , Cheng Jin , Yihui Wang , Zhixuan Chen , Zhengyu Zhang , Fuxiang Huang , Zhengrui Guo , Fengtao Zhou , Yingxue Xu , Xi Wang , Ronald Cheong Kin Chan , Li Liang , Hao Chen

Background: Cognitive biases in clinical decision-making significantly contribute to errors in diagnosis and suboptimal patient outcomes. Addressing these biases presents a formidable challenge in the medical field. Objective: This study…

Computation and Language · Computer Science 2024-05-14 Yu He Ke , Rui Yang , Sui An Lie , Taylor Xin Yi Lim , Hairil Rizal Abdullah , Daniel Shu Wei Ting , Nan Liu